{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T17:01:18Z","timestamp":1763830878870,"version":"3.41.0"},"reference-count":58,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[1969,8,1]],"date-time":"1969-08-01T00:00:00Z","timestamp":-13219200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1969,8]]},"DOI":"10.1093\/ajcn\/22.8.1070","type":"journal-article","created":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T09:13:43Z","timestamp":1516698823000},"page":"1070-1080","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Chronic Bovine Hypo- and Hypervitaminosis A and Cerebrospinal Fluid Pressure"],"prefix":"10.1016","volume":"22","author":[{"given":"H.D.","family":"EATON","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/22.8.1070_bib1","first-page":"1020","article-title":"Comparative pharmacology and cerebrospinal fluid.","volume":"26","author":"RALL","year":"1967","journal-title":"Federation Proc"},{"key":"10.1093\/ajcn\/22.8.1070_bib2","series-title":"Comparative Neuropathology","first-page":"21","article-title":"The cerebrospinal fluid","author":"FANKHAUSER","year":"1962"},{"key":"10.1093\/ajcn\/22.8.1070_bib3","first-page":"364","article-title":"The normal cerebrospinal fluid pressure and a method for its determination in cattle.","volume":"3","author":"SYKES","year":"1942","journal-title":"Am. J. Vet. Res."},{"key":"10.1093\/ajcn\/22.8.1070_bib4","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3168\/jds.S0022-0302(65)88169-3","article-title":"Association between age and cisternal cerebrospinal fluid pressure in Holstein male calves.","volume":"48","author":"CALHOUN","year":"1965","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib5","series-title":"Physiology of the Cerebrospinal Fluid.","article-title":"Physiology of the Cerebrospinal Fluid.","author":"DAVSON","year":"1967"},{"key":"10.1093\/ajcn\/22.8.1070_bib6","series-title":"Vitamin A.","article-title":"Vitamin A.","author":"MOORE","year":"1957"},{"key":"10.1093\/ajcn\/22.8.1070_bib7","series-title":"The Cerebrospinal Fluid","first-page":"168","article-title":"Vitamins and the cerebrospinal fluid","author":"MILLEN","year":"1958"},{"key":"10.1093\/ajcn\/22.8.1070_bib8","doi-asserted-by":"crossref","first-page":"889","DOI":"10.3168\/jds.S0022-0302(54)91341-7","article-title":"Relative value of carotene from alfalfa and vitamin A from a dry carrier fed at minimum levels to Holstein calves.","volume":"37","author":"ROUSSEAU","year":"1954","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib9","series-title":"Bovine Vitamin A Deficiency and Urine Composition","article-title":"Bovine Vitamin A Deficiency and Urine Composition","author":"WOELFEL","year":"1968"},{"key":"10.1093\/ajcn\/22.8.1070_bib10","first-page":"978","article-title":"Accleration of bovine hypovitaminosis A.","volume":"51","author":"CALHOUN","year":"1968","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib11","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/jn\/82.2.263","article-title":"Effect of vitamin A and vitamin A acid on cerebrospinal fluid pressure and blood and liver vitamin A concentrations in the pig.","volume":"82","author":"NELSON","year":"1964","journal-title":"J. Nutr."},{"key":"10.1093\/ajcn\/22.8.1070_bib12","doi-asserted-by":"crossref","first-page":"607","DOI":"10.3168\/jds.S0022-0302(52)93744-2","article-title":"Blood levels of ascorbic acid and vitamin A during vitamin A depletion and effect of administration of ascorbic acid during terminal vitamin A depletion in the dairy cow.","volume":"35","author":"EATON","year":"1952","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib13","first-page":"343","article-title":"The pathology of experimental hypovitaminosis A in young dairy animals.","volume":"14","author":"HELMBOLDT","year":"1953","journal-title":"Am. J. Vet. Res."},{"key":"10.1093\/ajcn\/22.8.1070_bib14","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.3168\/jds.S0022-0302(60)90418-5","article-title":"Effect of duration of deficient carotene intake upon subsequent utilization of carotene from alfalfa by Holstein calves.","volume":"43","author":"GRIFO","year":"1960","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib15","doi-asserted-by":"crossref","first-page":"630","DOI":"10.3168\/jds.S0022-0302(60)90214-9","article-title":"Some biochemical constituents in serum, cerebrospinal fluid and aqueous humor of vitamin A deficient Holstein calves.","volume":"43","author":"DEHORITY","year":"1960","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib16","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3168\/jds.S0022-0302(62)89334-5","article-title":"Effect of level of ration intake and duration of vitamin A deficiency upon some biochemical constituents in serum, cerebrospinal fluid and aqueous humor of Holstein calves fed fixed carotene intakes.","volume":"45","author":"HAZZARD","year":"1962","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib17","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.3168\/jds.S0022-0302(61)89892-5","article-title":"Association between cerebrospinal fluid pressure and plasma vitamin A concentration of Holstein calves fed fixed intakes of carotene.","volume":"44","author":"EATON","year":"1961","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib18","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1093\/jn\/34.6.603","article-title":"Some observations on beef cattle affected with generalized edema or anasarca due to vitamin A deficiency.","volume":"34","author":"MADSEN","year":"1947","journal-title":"J. Nutr."},{"key":"10.1093\/ajcn\/22.8.1070_bib19","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1093\/jn\/76.4.325","article-title":"Effect of vitamin A intake on some biochemical and physiological changes in swine.","volume":"76","author":"NELSON","year":"1962","journal-title":"J. Nutr."},{"key":"10.1093\/ajcn\/22.8.1070_bib20","doi-asserted-by":"crossref","first-page":"872","DOI":"10.3168\/jds.S0022-0302(62)89513-7","article-title":"Influx of sodium thiocyanate into cerebrospinal fluid in normal and vitamin A deficient calves.","volume":"45","author":"BITMAN","year":"1962","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib21","doi-asserted-by":"crossref","first-page":"879","DOI":"10.3168\/jds.S0022-0302(62)89514-9","article-title":"Effect of vitamin A deficiency on efflux of sodium thiocyanate from cerebrospinal fluid.","volume":"45","author":"BITMAN","year":"1962","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib22","doi-asserted-by":"crossref","first-page":"882","DOI":"10.3168\/jds.S0022-0302(62)89515-0","article-title":"Replacement and absorption of cerebrospinal fluid in normal and vitamin A deficient calves.","volume":"45","author":"OKAMOTO","year":"1962","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib23","series-title":"Rates of Formation and Absorption of Cerebrospinal Fluid in Hypovitaminosis A","article-title":"Rates of Formation and Absorption of Cerebrospinal Fluid in Hypovitaminosis A","author":"CALHOUN","year":"1966"},{"key":"10.1093\/ajcn\/22.8.1070_bib24","series-title":"Physiology of the Cerebrospinal Fluid.","first-page":"126","article-title":"Physiology of the Cerebrospinal Fluid.","author":"DAVSON","year":"1967"},{"key":"10.1093\/ajcn\/22.8.1070_bib25","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.3168\/jds.S0022-0302(67)87653-7","article-title":"Rates of formation and absorption of cerebrospinal fluid in bovine hypovitaminosis A.","volume":"50","author":"CALHOUN","year":"1967","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib26","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.3168\/jds.S0022-0302(68)87277-7","article-title":"Osmotic flow during ventriculocisternal perfusion of vitamin A deficient calves.","volume":"51","author":"CALHOUN","year":"1968","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib27","series-title":"Physiology of the Cerebrospinal Fluid.","article-title":"Physiology of the Cerebrospinal Fluid.","author":"DAVSON","year":"1967"},{"key":"10.1093\/ajcn\/22.8.1070_bib28","unstructured":"HAYES, K. C., S. W. NIELSEN AND H. D. EATON. Pathogenesis of the optic nerve lesion in vitamin-A deficient calves. A.M.A. Arch. Ophthalmol. In press."},{"key":"10.1093\/ajcn\/22.8.1070_bib29","series-title":"Biochemical Constituents of the Dura Mater in Vitamin A Deficiency","article-title":"Biochemical Constituents of the Dura Mater in Vitamin A Deficiency","author":"COUSINS","year":"1968"},{"key":"10.1093\/ajcn\/22.8.1070_bib30","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/ajcn\/6.4.335","article-title":"Hypervitaminosis A: Its broadening spectrum.","volume":"6","author":"JEGHERS","year":"1958","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/22.8.1070_bib31","first-page":"183","article-title":"Toxicity of vitamins. In: Toxicants Occurring Naturally in Foods, by Food Protection Committee, Food and Nutrition Board. Washington, D.C.:","volume":"1354","author":"OSTWALD","year":"1966","journal-title":"Natl. Acad. Sci.-Natl. Res. Council Publ."},{"key":"10.1093\/ajcn\/22.8.1070_bib32","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3168\/jds.S0022-0302(64)88673-2","article-title":"Chronic hypervitaminosis A in Holstein male calves.","volume":"47","author":"HAZZARD","year":"1964","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib33","doi-asserted-by":"crossref","first-page":"783","DOI":"10.3168\/jds.S0022-0302(64)88764-6","article-title":"Cisternal and intraventricular cerebrospinal fluid pressures in chronic bovine hypervitaminosis A.","volume":"47","author":"GREY","year":"1964","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib34","doi-asserted-by":"crossref","first-page":"729","DOI":"10.3168\/jds.S0022-0302(65)88329-1","article-title":"Cisternal cerebrospinal fluid pressure during development of chronic bovine hypervitaminosis A.","volume":"48","author":"CALHOUN","year":"1965","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib35","article-title":"Reversal of chronic bovine hypervitaminosis A.","volume":"409","author":"HALL","year":"1968","journal-title":"Univ. Conn. Agr. Expt. Sta. Bull."},{"key":"10.1093\/ajcn\/22.8.1070_bib36","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.3168\/jds.S0022-0302(67)87751-8","article-title":"Rates of formation and absorption of cerebrospinal fluid in chronic hypervitaminosis A.","volume":"50","author":"HURT","year":"1967","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib37","first-page":"400","article-title":"Chronic hypervitaminosis A in weanling pigs.","author":"HURT","year":"1966","journal-title":"Univ. Conn. Agr. Expt. Sta. Bull."},{"key":"10.1093\/ajcn\/22.8.1070_bib38","series-title":"Vitamin A.","article-title":"Vitamin A.","author":"MOORE","year":"1957"},{"key":"10.1093\/ajcn\/22.8.1070_bib39","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0083-6729(08)61009-2","article-title":"The biochemistry and pathology of hypervitaminosis A.","volume":"12","author":"NIEMAN","year":"1954","journal-title":"Vitamins Hormones"},{"key":"10.1093\/ajcn\/22.8.1070_bib40","first-page":"106","article-title":"Effects of vitamin A deficiency and hypervitaminosis A in animals","volume":"I","author":"WOLBACH","year":"1954"},{"key":"10.1093\/ajcn\/22.8.1070_bib41","first-page":"315","article-title":"Arachnoid granulations in sheep.","volume":"99","author":"JAYATILAKA","year":"1965","journal-title":"J. Anat."},{"key":"10.1093\/ajcn\/22.8.1070_bib42","first-page":"635","article-title":"An electron microscopic study of sheep arachnoid granulations.","volume":"99","author":"JAYATILAKA","year":"1965","journal-title":"J. Anat."},{"key":"10.1093\/ajcn\/22.8.1070_bib43","series-title":"Cerebrospinal Fluid and the Regulation of Ventilation","first-page":"395","article-title":"The cerebrospinal fluid circulation","author":"BERING","year":"1965"},{"key":"10.1093\/ajcn\/22.8.1070_bib44","series-title":"Cerebrospinal Fluid and the Regulation of Ventilation","first-page":"385","article-title":"Formation and drainage of the cerebrospinal fluid: Basic concepts","author":"DAVSON","year":"1965"},{"key":"10.1093\/ajcn\/22.8.1070_bib45","doi-asserted-by":"crossref","first-page":"666","DOI":"10.3168\/jds.S0022-0302(50)91952-7","article-title":"Parotid gland lesions in experimental bovine vitamin A deficiency.","volume":"33","author":"JUNGHERR","year":"1950","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib46","first-page":"223","article-title":"Parotid duct metaplasia in marginal bovine vitamin A deficiency.","volume":"27","author":"NIELSEN","year":"1966","journal-title":"Am. J. Vet. Res."},{"key":"10.1093\/ajcn\/22.8.1070_bib47","series-title":"Physiology of the Cerebrospinal Fluid.","first-page":"377","article-title":"Physiology of the Cerebrospinal Fluid.","author":"DAVSON","year":"1967"},{"key":"10.1093\/ajcn\/22.8.1070_bib48","series-title":"Topographic Brain Chemistry.","first-page":"447","article-title":"Topographic Brain Chemistry.","author":"FRIEDE","year":"1966"},{"key":"10.1093\/ajcn\/22.8.1070_bib49","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0031-6997(25)07166-2","article-title":"The metabolism of vitamin A.","volume":"19","author":"OLSON","year":"1967","journal-title":"Pharmacol. Rev."},{"key":"10.1093\/ajcn\/22.8.1070_bib50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0003-9861(68)90097-0","article-title":"Effect of vitamin A on the mucopolysaccharides of lung tissue.","volume":"123","author":"DE LUCA","year":"1968","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1093\/ajcn\/22.8.1070_bib51","doi-asserted-by":"crossref","first-page":"893","DOI":"10.3168\/jds.S0022-0302(41)95473-5","article-title":"Some ocular changes and deficiency manifestations in mature cows fed a ration deficient in vitamin A.","volume":"24","author":"MOORE","year":"1941","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/22.8.1070_bib52","series-title":"A Story of Nutritional Research.","first-page":"V","article-title":"A Story of Nutritional Research.","author":"MELLANBY","year":"1950"},{"key":"10.1093\/ajcn\/22.8.1070_bib53","first-page":"450","article-title":"Observations on the lesions in vitamin A deficient adult fowls with particular reference to changes in bone and central nervous system.","volume":"48","author":"HOWELL","year":"1967","journal-title":"Brit. J. Exptl. Pathol."},{"key":"10.1093\/ajcn\/22.8.1070_bib54","doi-asserted-by":"crossref","first-page":"3404","DOI":"10.1016\/S0021-9258(18)93322-3","article-title":"Adrenal \u22065-3\u03b2-hydroxysteroid dehydrogenase as related to vitamin A.","volume":"243","author":"ROGERS","year":"1968","journal-title":"J. Biol. Chem."},{"key":"10.1093\/ajcn\/22.8.1070_bib55","series-title":"Histology","first-page":"379","article-title":"Histology","author":"HAM","year":"1953"},{"key":"10.1093\/ajcn\/22.8.1070_bib56","first-page":"446","article-title":"Pathology of the skull, radius and rib in hypervitaminosis A of young calves.","volume":"2","author":"GREY","year":"1965","journal-title":"Pathol. Vet."},{"key":"10.1093\/ajcn\/22.8.1070_bib57","first-page":"1017","article-title":"Pathological features of the choroid plexus. 1. Cytochemical effects of hypervitaminosis A.","volume":"43","author":"BECKER","year":"1963","journal-title":"Am. J. Pathol."},{"key":"10.1093\/ajcn\/22.8.1070_bib58","first-page":"326","article-title":"Histochemical changes in the choroid plexus in hypervitaminosis A.","volume":"41","author":"SUTTON","year":"1965","journal-title":"Bull. N.Y. Acad. Med."}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523323797?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523323797?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/22\/8\/1070\/24158715\/1070.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T23:45:59Z","timestamp":1751240759000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523323797"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,8]]},"references-count":58,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1969,8]]}},"alternative-id":["S0002916523323797"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/22.8.1070","relation":{},"ISSN":["0002-9165"],"issn-type":[{"type":"print","value":"0002-9165"}],"subject":[],"published":{"date-parts":[[1969,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic Bovine Hypo- and Hypervitaminosis A and Cerebrospinal Fluid Pressure","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/22.8.1070","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1969 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}