{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:59:06Z","timestamp":1760889546196},"reference-count":47,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[1973,11,1]],"date-time":"1973-11-01T00:00:00Z","timestamp":120960000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1973,11]]},"DOI":"10.1093\/ajcn\/26.11.1224","type":"journal-article","created":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T08:43:46Z","timestamp":1516610626000},"page":"1224-1228","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Lactose feeding in lactose-intolerant monkeys"],"prefix":"10.1016","volume":"26","author":[{"given":"Chi-Pang","family":"Wen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irena","family":"Antonowicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Tovar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert B.","family":"McGandy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanley N.","family":"Gershoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/26.11.1224_bib1","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1001\/jama.1966.03110120074017","article-title":"A racial difference in incidence of lactase deficiency","volume":"197","author":"BAYLESS","year":"1966","journal-title":"J. Am. Med. Assoc"},{"key":"10.1093\/ajcn\/26.11.1224_bib2","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0140-6736(65)90922-0","article-title":"Lactase deficiency in the adult: a common occurrence.","volume":"1","author":"CUATRECASAS","year":"1965","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/26.11.1224_bib3","first-page":"246","article-title":"Intestinal lactase deficiency among East Indians. An adaptive rather than a genetically inherited phenomenon?","volume":"53","author":"MURTHY","year":"1970","journal-title":"Am. J. Gastroenterol"},{"key":"10.1093\/ajcn\/26.11.1224_bib4","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/222382a0","article-title":"Asian lactose intolerance and its relationship to intake of lactose","volume":"222","author":"BOLIN","year":"1969","journal-title":"Nature"},{"key":"10.1093\/ajcn\/26.11.1224_bib5","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/ajcn\/22.2.122","article-title":"Lactose intolerance in South American Indians.","volume":"22","author":"ALZATE","year":"1969","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/26.11.1224_bib6","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0140-6736(66)90888-9","article-title":"Tribal incidence of lactose deficiency in Uganda.","volume":"1","author":"COOK","year":"1966","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/26.11.1224_bib7","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1001\/archinte.1967.00300030003003","article-title":"Isolated lactase deficiency: correlation of laboratory studies and clinical data","volume":"120","author":"WELSH","year":"1967","journal-title":"Arch. Internal Med"},{"key":"10.1093\/ajcn\/26.11.1224_bib8","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1056\/NEJM196706082762303","article-title":"Lactose intolerance in healthy children","volume":"276","author":"HUANG","year":"1967","journal-title":"New Engl. J. Med"},{"key":"10.1093\/ajcn\/26.11.1224_bib9","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1126\/science.160.3823.83.b","article-title":"Milk and lactose intolerance in healthy Orientals.","volume":"160","author":"HUANG","year":"1968","journal-title":"Science"},{"key":"10.1093\/ajcn\/26.11.1224_bib10","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S0016-5085(66)80073-2","article-title":"Lactose tolerance tests in adults with normal lactase activity","volume":"50","author":"NEWCOMER","year":"1966","journal-title":"Gastroenterology"},{"key":"10.1093\/ajcn\/26.11.1224_bib11","first-page":"138","article-title":"Intestinal lactase\u2013an inducibleenzyme?","volume":"28","year":"1970","journal-title":"Nutr. Rev."},{"key":"10.1093\/ajcn\/26.11.1224_bib12","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1007\/BF02233204","article-title":"Primary adult lactose intolerance and the milking habit: a problem in biological and cultural interrelations. I. Review of the medical research","volume":"14","author":"SIMOONS","year":"1969","journal-title":"Am. J. Digest. Diseases"},{"key":"10.1093\/ajcn\/26.11.1224_bib13","first-page":"605","article-title":"Primary lactase deficiency: genetic or acquired?","volume":"60","author":"BOLIN","year":"1971","journal-title":"Gastroenterology"},{"key":"10.1093\/ajcn\/26.11.1224_bib14","first-page":"71","article-title":"Lactose and lactase. Sci. Am.","volume":"227","author":"KRETCHMER","year":"1972"},{"key":"10.1093\/ajcn\/26.11.1224_bib15","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1093\/ajcn\/22.5.638","article-title":"Lactase deficiency in Thailand: effect of prolonged lactose feeding.","volume":"22","author":"KEUSCH","year":"1969","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/26.11.1224_bib16","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1093\/ajcn\/25.1.114","article-title":"Lactase deficiency in Indians.","volume":"25","author":"REDDY","year":"1972","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/26.11.1224_bib17","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/BF02232965","article-title":"Effect of a nonlactose diet on human intestinal disaccharidase activity","volume":"13","author":"KNUDSEN","year":"1968","journal-title":"Am. J. Digest. Diseases"},{"key":"10.1093\/ajcn\/26.11.1224_bib18","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/ajcn\/22.1.99","article-title":"Diet and disaccharidases.","volume":"22","author":"G","year":"1969","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/26.11.1224_bib19","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1038\/221758b0","article-title":"Lactose intolerance in Thailand","volume":"221","author":"FLATZ","year":"1969","journal-title":"Nature"},{"key":"10.1093\/ajcn\/26.11.1224_bib20","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/S0016-5085(71)80127-0","article-title":"Adult lactase deficiency: genetic control or adaptive response?","volume":"60","author":"ROSENSWEIG","year":"1971","journal-title":"Gastroenterology"},{"key":"10.1093\/ajcn\/26.11.1224_bib21","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/S0016-5085(71)80066-5","article-title":"Lactose intolerance and milk drinking habits","volume":"60","author":"BAYLESS","year":"1971","journal-title":"Gastroenterology"},{"key":"10.1093\/ajcn\/26.11.1224_bib22","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1136\/adc.46.246.218","article-title":"Jejunal disaccharidase activities in children with marasmus and with kwashiorkor. Response to treatment","volume":"46","author":"JAMES","year":"1971","journal-title":"Arch. Disease Childhood"},{"key":"10.1093\/ajcn\/26.11.1224_bib23","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1093\/ajcn\/25.7.664","article-title":"Acquired disaccharide intolerance in children with malnutrition.","volume":"25","author":"BILIR","year":"1972","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/26.11.1224_bib24","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0016-5085(19)33872-7","article-title":"Adaptation of intestinal lactase in the rat","volume":"57","author":"BOLIN","year":"1969","journal-title":"Gastroenterology"},{"key":"10.1093\/ajcn\/26.11.1224_bib25","first-page":"7","article-title":"Adaptation de la lactase intestinale a 1\u2019administration de lactose chez le rat adulte","volume":"22","author":"GIRARDET","year":"1964","journal-title":"Helv. Physiol. Pharmacol. Acta"},{"key":"10.1093\/ajcn\/26.11.1224_bib26","first-page":"36","article-title":"Stimulation of lactose formation by force feeding of lactose","volume":"16","author":"CAIN","year":"1968","journal-title":"Clin. Res."},{"key":"10.1093\/ajcn\/26.11.1224_bib27","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1152\/ajplegacy.1956.188.1.49","article-title":"Effects of feeding a diet containing lactose upon \u03b2-D-galactosidase activity and organ development in the rat digestive tract.","volume":"188","author":"FISHER","year":"1957","journal-title":"Am. J. Physiol."},{"key":"10.1093\/ajcn\/26.11.1224_bib28","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S0021-9258(18)51369-7","article-title":"Choline in the nutrition of chicks.","volume":"138","author":"HEGSTED","year":"1941","journal-title":"J. Biol. Chem."},{"key":"10.1093\/ajcn\/26.11.1224_bib29","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/0003-2697(64)90115-0","article-title":"Method for assay of intestinal disaccharidases.","volume":"7","author":"DAHLQVIST","year":"1964","journal-title":"Anal. Biochem."},{"key":"10.1093\/ajcn\/26.11.1224_bib30","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1542\/peds.36.6.911","article-title":"Quantitative assay of disaccharidase activities of small intestine mucosal biopsy specimens in infancy and childhood","volume":"36","author":"TOWNLEY","year":"1965","journal-title":"Pediatrics"},{"key":"10.1093\/ajcn\/26.11.1224_bib31","first-page":"159","article-title":"Rat-liver lysosomal\u03b2-glucosidase: a membrane enzyme","volume":"151","author":"BECK","year":"1968","journal-title":"Biochem. Biophys. Acta"},{"key":"10.1093\/ajcn\/26.11.1224_bib32","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent.","volume":"193","author":"LOWRY","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1093\/ajcn\/26.11.1224_bib33","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/BF01473099","article-title":"Vergleichende Untersuchungen zur quantitativen Eiweissbestimmung in Liquor und eiweissarmen L\u00f6-sungen","volume":"33","author":"KREUTZ","year":"1955","journal-title":"Klin. Wochschr."},{"key":"10.1093\/ajcn\/26.11.1224_bib34","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0016-5085(19)34363-X","article-title":"Distribution of disaccharidase activities in the small bowel of normal and lactase deficient subjects","volume":"51","author":"NEWCOMER","year":"1966","journal-title":"Gastroenterology"},{"key":"10.1093\/ajcn\/26.11.1224_bib35","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1542\/peds.42.3.492","article-title":"Lactase deficiency in patients with cystic fibrosis","volume":"42","author":"ANTONOWICZ","year":"1968","journal-title":"Pediatrics"},{"key":"10.1093\/ajcn\/26.11.1224_bib36","first-page":"64","article-title":"Studies on intestinal disaccharidases. Part II. Specificity of monkey intestinal\u03b2-galactosidases","volume":"4","author":"SWAMINATHAN","year":"1969","journal-title":"Indian J. Biochem"},{"key":"10.1093\/ajcn\/26.11.1224_bib37","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0006-3002(62)90097-5","article-title":"Studies of small intestine during development. I. Distribution and activity of \u03b2-galactosidase","volume":"62","author":"DOELL","year":"1962","journal-title":"Biochem. Biophys. Acta"},{"key":"10.1093\/ajcn\/26.11.1224_bib38","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1172\/JCI105521","article-title":"Effect of diet upon intestinal disaccharidases and disaccharide absorption.","volume":"46","author":"DEREN","year":"1967","journal-title":"J. Clin. Invest."},{"key":"10.1093\/ajcn\/26.11.1224_bib39","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1172\/JCI105910","article-title":"Control of jejunal sucrase and maltase activity by dietary sucrose or fructose in man.","volume":"47","author":"ROSENSWEIG","year":"1968","journal-title":"J. Clin. Invest."},{"key":"10.1093\/ajcn\/26.11.1224_bib40","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3168\/jds.S0022-0302(53)91447-7","article-title":"Effect of previous lactose feeding upon intestinal absorption of lactose in the rat","volume":"36","author":"FISCHER","year":"1953","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/26.11.1224_bib41","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1093\/jn\/103.3.392","article-title":"Effect of dietary lactose on intestinal lactase activity in young rats","volume":"103","author":"LEICHTER","year":"1973","journal-title":"J. Nutr."},{"key":"10.1093\/ajcn\/26.11.1224_bib42","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1113\/jphysiol.1906.sp001178","article-title":"On the presence of lactase in the intestines of animals and on the adaptation of the intestine to lactose.","volume":"35","author":"PLIMMER","year":"1906","journal-title":"J. Physiol."},{"key":"10.1093\/ajcn\/26.11.1224_bib43","first-page":"290","article-title":"The detrimental effect of lactose. II. Quantitative lactase determinations in various mammals","volume":"2","author":"DEGROOT","year":"1957","journal-title":"Neth. Milk Dairy J."},{"key":"10.1093\/ajcn\/26.11.1224_bib44","doi-asserted-by":"crossref","first-page":"789","DOI":"10.3168\/jds.S0022-0302(64)88765-8","article-title":"Effect of level of lactose upon lactase concentration in the small intestines of young calves","volume":"47","author":"HUBER","year":"1964","journal-title":"J. Dairy Sci."},{"key":"10.1093\/ajcn\/26.11.1224_bib45","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/S0016-5085(72)80080-5","article-title":"Lactase in man: a nonadaptable enzyme","volume":"62","author":"GILAT","year":"1972","journal-title":"Gastroenterology"},{"key":"10.1093\/ajcn\/26.11.1224_bib46","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S0016-5085(66)80073-2","article-title":"Lactose tolerance tests in adults with normal lactase activity","volume":"50","author":"NEWCOMER","year":"1966","journal-title":"Gastroenterology"},{"key":"10.1093\/ajcn\/26.11.1224_bib47","series-title":"Statistical Methods","author":"SNEDECOR","year":"1968"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523334257?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523334257?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/26\/11\/1224\/24154564\/1224.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T13:50:50Z","timestamp":1698760250000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523334257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,11]]},"references-count":47,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1973,11]]}},"alternative-id":["S0002916523334257"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/26.11.1224","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[1973,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lactose feeding in lactose-intolerant monkeys","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/26.11.1224","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1973 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}