{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:47:24Z","timestamp":1789915644579,"version":"4.0.1"},"reference-count":39,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[1981,10,1]],"date-time":"1981-10-01T00:00:00Z","timestamp":370742400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1981,10,1]],"date-time":"1981-10-01T00:00:00Z","timestamp":370742400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1981,10]]},"DOI":"10.1093\/ajcn\/34.10.2117","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T10:13:05Z","timestamp":1516097585000},"page":"2117-2126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["Effect of renutrition on humoral and cell-mediated immunity in severely malnourished children"],"prefix":"10.1016","volume":"34","author":[{"given":"D N","family":"McMurray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R R","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M A","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/34.10.2117_bib1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/10408397909527275","article-title":"The effects of malnutrition on secretory and cellular immune processes","volume":"12","author":"Watson","year":"1979","journal-title":"Crit Rev Food Sci Nutr"},{"key":"10.1093\/ajcn\/34.10.2117_bib2","series-title":"Malnutrition and the immune response","author":"Suskind","year":"1977"},{"key":"10.1093\/ajcn\/34.10.2117_bib3","series-title":"Nutrition, immunity and infection","author":"Chandra","year":"1977"},{"key":"10.1093\/ajcn\/34.10.2117_bib4","first-page":"248","article-title":"Plasma levels of complement components and complement haemolytic activity in protein-energy malnutrition","volume":"34","author":"Haller","year":"1978","journal-title":"Clin Exp Immunol"},{"key":"10.1093\/ajcn\/34.10.2117_bib5","series-title":"Malnutrition and the immune response","first-page":"309","article-title":"The complement system in protein-calorie malnutrition: a review","author":"Sirisinha","year":"1977"},{"key":"10.1093\/ajcn\/34.10.2117_bib6","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1093\/ajcn\/30.12.1944","article-title":"Effect of moderate malnutrition on concentrations of immunoglobulins and enzymes in tears and saliva of young Colombia children","volume":"30","author":"McMurray","year":"1977","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/34.10.2117_bib7","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3181\/00379727-157-40024","article-title":"Influence of malnutrition on the concentration of IgA, lysozyme, amylase and aminopeptidase in children\u2019s tears","volume":"157","author":"Watson","year":"1978","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1093\/ajcn\/34.10.2117_bib8","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1651-2227.1979.tb04975.x","article-title":"Interactions of nutrition, infection and immune response","volume":"68","author":"Chandra","year":"1979","journal-title":"Acta Paediatr Scand"},{"key":"10.1093\/ajcn\/34.10.2117_bib9","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/ajcn\/34.1.68","article-title":"Development of impaired cell-mediated immunity in mild and moderate malnutrition","volume":"34","author":"McMurray","year":"1981","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/34.10.2117_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0090-1229(76)90143-4","article-title":"Analytical review: host defence mechanisms in protein-energy malnutrition","volume":"5","author":"Douglas","year":"1976","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1093\/ajcn\/34.10.2117_bib11","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0140-6736(76)91791-8","article-title":"Protein and calorie malnutrition, cell-mediated immunity and B.C.G. vaccination in children from West Bengal","volume":"2","author":"Sinha","year":"1976","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/34.10.2117_bib12","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF00466270","article-title":"Persistent cell-mediated immune deficiency following infantile stress during the first six months of life","volume":"122","author":"Dutz","year":"1976","journal-title":"EurJ Pediatr"},{"key":"10.1093\/ajcn\/34.10.2117_bib13","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1136\/bmj.4.5786.527","article-title":"Impaired cellular immunity in kwashiorkor with improvement after therapy","volume":"4","author":"Geefhuysen","year":"1971","journal-title":"Br Med J"},{"key":"10.1093\/ajcn\/34.10.2117_bib14","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/S0140-6736(73)90326-7","article-title":"Mechanisms of defective delayed cutaneous hypersensitivity in children with protein-calorie malnutrition","volume":"1","author":"Edelman","year":"1973","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/34.10.2117_bib15","first-page":"1375","article-title":"Pattern of biochemical and immune recovery in protein calorie malnutrition","volume":"48","author":"Parent","year":"1974","journal-title":"S Afr Med J"},{"key":"10.1093\/ajcn\/34.10.2117_bib16","first-page":"63","article-title":"The influence of renutrition on biochemical and hematological parameters and morbidity in severely malnourished children","volume":"21","author":"Reyes","year":"1980","journal-title":"Nutr Rep Int"},{"key":"10.1093\/ajcn\/34.10.2117_bib17","series-title":"Advances in pediatrics","first-page":"131","article-title":"Malnutrition in infancy and childhood with special reference to kwashiorkor","author":"Gomez","year":"1955"},{"key":"10.1093\/ajcn\/34.10.2117_bib18","first-page":"79","article-title":"Simplified field assessment of nutritional status in early childhood: practical suggestions for developing countries","volume":"55","author":"Miller","year":"1977","journal-title":"Bull WHO"},{"key":"10.1093\/ajcn\/34.10.2117_bib19","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin-phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1093\/ajcn\/34.10.2117_bib20","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0009-8981(71)90365-2","article-title":"Albumin standards and the measurement of serum albumin with bromocresol green","volume":"31","author":"Doumas","year":"1971","journal-title":"Clin Chem Acta"},{"key":"10.1093\/ajcn\/34.10.2117_bib21","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0019-2791(65)90004-2","article-title":"Immunochemical quantitation of antigens by single radial immunodiffusion","volume":"2","author":"Mancini","year":"1965","journal-title":"J Immunochem"},{"key":"10.1093\/ajcn\/34.10.2117_bib22","first-page":"137","article-title":"Simplified whole blood method for evaluating in vitro lymphocyte reactivity of laboratory animals","volume":"11","author":"Han","year":"1972","journal-title":"Clin Exp Immunol"},{"key":"10.1093\/ajcn\/34.10.2117_bib23","first-page":"431","article-title":"Microtechnique for quantitative evaluation of in vitro lymphocyte transformation","volume":"7","author":"Junge","year":"1970","journal-title":"Clin Exp Immunol"},{"key":"10.1093\/ajcn\/34.10.2117_bib24","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1056\/NEJM197202242860804","article-title":"A method for dinitrochlorobenzene contact sensitization","volume":"286","author":"Catalona","year":"1972","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/34.10.2117_bib25","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1136\/adc.47.253.429","article-title":"Lymphocyte transformation in malnourished children","volume":"47","author":"Sellmeyer","year":"1972","journal-title":"Arch Dis Child"},{"key":"10.1093\/ajcn\/34.10.2117_bib26","first-page":"647","article-title":"PHA-induced lymphocyte transformations in leukocyte cultures from malarious, malnourished and control Gambian children","volume":"17","author":"Moore","year":"1974","journal-title":"Clin Exp Immunol"},{"key":"10.1093\/ajcn\/34.10.2117_bib27","doi-asserted-by":"crossref","first-page":"699","DOI":"10.5694\/j.1326-5377.1975.tb106221.x","article-title":"Deficiency of immunological and phagocytic function in Aboriginal children with protein-calorie malnutrition","volume":"2","author":"J\u00f3se","year":"1975","journal-title":"Med J Aust"},{"key":"10.1093\/ajcn\/34.10.2117_bib28","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1093\/ajcn\/28.2.89","article-title":"Immunologic responses in malnourished children","volume":"28","author":"Neumann","year":"1975","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/34.10.2117_bib29","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0090-1229(76)90146-X","article-title":"In vitro studies of lymphocytes from children with kwashiorkor","volume":"2","author":"Sch\u00f6pfer","year":"1976","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1093\/ajcn\/34.10.2117_bib30","doi-asserted-by":"crossref","first-page":"61520","DOI":"10.1093\/ajcn\/27.6.615","article-title":"Impaired cellular immunity in marasmic infants","volume":"27","author":"Schlesinger","year":"1974","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/34.10.2117_bib31","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/S0022-3476(72)80262-2","article-title":"Immunocomp\u00e9tence in undemutrition","volume":"81","author":"Chandra","year":"1972","journal-title":"J Pediatr"},{"key":"10.1093\/ajcn\/34.10.2117_bib32","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1136\/bmj.3.5931.608","article-title":"Rosette-forming T lymphocytes and cell-mediated immunity in malnutrition","volume":"3","author":"Chandra","year":"1974","journal-title":"Br J Med"},{"key":"10.1093\/ajcn\/34.10.2117_bib33","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1136\/adc.50.3.225","article-title":"Serum complement and immunoconglutinin in malnutrition","volume":"50","author":"Chandra","year":"1975","journal-title":"Arch Dis Child"},{"key":"10.1093\/ajcn\/34.10.2117_bib34","first-page":"1278","article-title":"A study of immunoglobulins in protein calorie malnutrition","volume":"60","author":"Samuel","year":"1972","journal-title":"Indian J Med Res"},{"key":"10.1093\/ajcn\/34.10.2117_bib35","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1093\/ajcn\/29.8.836","article-title":"Immunoglobulins and antibody response in children with protein-calorie malnutrition","volume":"29","author":"Suskind","year":"1976","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/34.10.2117_bib36","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/ajcn\/29.10.1089","article-title":"Complement activity in protein-calorie malnutrition","volume":"29","author":"Suskind","year":"1976","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/34.10.2117_bib37","first-page":"13","article-title":"Studies of cell-mediated immunity and allergy in protein energy malnutrition I. Cell-mediated delayed hypersensitivity","volume":"77","author":"Abbassy","year":"1974","journal-title":"J Trop Med Hyg"},{"key":"10.1093\/ajcn\/34.10.2117_bib38","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1097\/00000658-197402000-00010","article-title":"The effect of dietary protein depletion on immunocomp\u00e9tence","volume":"79","author":"Law","year":"1974","journal-title":"Ann Surg"},{"key":"10.1093\/ajcn\/34.10.2117_bib39","first-page":"59","article-title":"Depression of tuberculin reaction in mild and moderate protein-calorie malnourished children following BCG vaccination","volume":"137","author":"Ziegler","year":"1975","journal-title":"Johns Hopkins Med J"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523431486?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523431486?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/34\/10\/2117\/24157321\/2117.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T23:11:37Z","timestamp":1718406697000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523431486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,10]]},"references-count":39,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1981,10]]}},"alternative-id":["S0002916523431486"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/34.10.2117","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[1981,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of renutrition on humoral and cell-mediated immunity in severely malnourished children","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/34.10.2117","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1981 American Society for Nutrition. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}