{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:18:55Z","timestamp":1790853535483,"version":"4.1.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1998,5,1]],"date-time":"1998-05-01T00:00:00Z","timestamp":893980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1998,5,1]],"date-time":"1998-05-01T00:00:00Z","timestamp":893980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"vor","delay-in-days":9063,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1998,5]]},"DOI":"10.1093\/ajcn\/67.5.1041s","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T14:27:47Z","timestamp":1515162467000},"page":"1041S-1045S","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":139,"title":["Copper intake and assessment of copper status"],"prefix":"10.1016","volume":"67","author":[{"given":"DB","family":"Milne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/67.5.1041S_bib1","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1093\/ajcn\/32.4.856","article-title":"On the assessment of zinc and copper nutriture in man.","volume":"32","author":"Solomons","year":"1979","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1146\/annurev.nu.08.070188.001315","article-title":"Copper deficiency in humans.","volume":"8","author":"Danks","year":"1988","journal-title":"Annu Rev Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib3","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1093\/clinchem\/40.8.1479","article-title":"Assessment of copper nutritional status.","volume":"40","author":"Milne","year":"1994","journal-title":"Clin Chem"},{"key":"10.1093\/ajcn\/67.5.1041S_bib4","series-title":"Recommended dietary allowances.","year":"1989"},{"key":"10.1093\/ajcn\/67.5.1041S_bib5","series-title":"Copper metabolism.","first-page":"274","article-title":"Copper metabolism in human subjects","author":"Cartwright","year":"1950"},{"key":"10.1093\/ajcn\/67.5.1041S_bib6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/ajcn\/33.1.45","article-title":"The human requirement for copper. I. Healthy men fed conventional, American diets.","volume":"33","author":"Klevay","year":"1980","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib7","series-title":"Trace elements in man and animals. TEMA-7","first-page":"5.1","article-title":"The significance of copper deficiency in human nutrition and health.","author":"Mills","year":"1991"},{"key":"10.1093\/ajcn\/67.5.1041S_bib8","series-title":"Trace elements in man and animals. TEMA-8","first-page":"207","article-title":"Copper in the Western diet","author":"Klevay","year":"1993"},{"key":"10.1093\/ajcn\/67.5.1041S_bib9","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1001\/jama.1979.03290440038025","article-title":"Evidence of dietary copper and zinc deficiencies.","volume":"241","author":"Klevay","year":"1979","journal-title":"JAMA"},{"key":"10.1093\/ajcn\/67.5.1041S_bib10","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1093\/jn\/118.12.1522","article-title":"64Copper absorption by women fed intrinsically and extrinsically labeled goose meat, goose liver, peanut butter, and sunflower butter.","volume":"118","author":"Johnson","year":"1988","journal-title":"J Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib11","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/ajcn\/42.2.242","article-title":"Indices of copper status in humans consuming a typical American diet containing either fructose or starch.","volume":"42","author":"Reiser","year":"1985","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib12","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/S0271-5317(05)80039-9","article-title":"Effect of copper intake on balance, absorption, and status indices of copper in men.","volume":"10","author":"Milne","year":"1990","journal-title":"Nutr Res"},{"key":"10.1093\/ajcn\/67.5.1041S_bib13","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/0026-0495(84)90096-9","article-title":"Increased cholesterol in plasma in a young man during experimental copper depletion.","volume":"33","author":"Klevay","year":"1984","journal-title":"Metabolism"},{"key":"10.1093\/ajcn\/67.5.1041S_bib14","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1093\/ajcn\/51.4.658","article-title":"Copper status and urinary and salivary copper in young men at three levels of dietary copper.","volume":"51","author":"Turnlund","year":"1990","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib15","first-page":"371","article-title":"Decreased glucose tolerance in two men during experimental copper depletion.","volume":"33","author":"Klevay","year":"1986","journal-title":"Nutr Rep Int"},{"key":"10.1093\/ajcn\/67.5.1041S_bib16","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/S0271-5317(88)80126-X","article-title":"Effects of ascorbic acid supplements and a diet marginal in copper on indices of copper nutriture in women.","volume":"8","author":"Milne","year":"1988","journal-title":"Nutr Res"},{"key":"10.1093\/ajcn\/67.5.1041S_bib17","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/BF00636606","article-title":"Effects of copper on human autonomic cardiovascular function.","volume":"58","author":"Lukaski","year":"1988","journal-title":"Eur J Appl Physiol"},{"key":"10.1093\/ajcn\/67.5.1041S_bib18","first-page":"281","article-title":"Dietary sulfur amino acids, and genetic make-up or interindividual variation affect the response of men to copper depletion.","volume":"3","author":"Nielsen","year":"1990","journal-title":"J Trace Elem Exp Med"},{"key":"10.1093\/ajcn\/67.5.1041S_bib19","series-title":"Trace elements in man and animals. TEMA-7","first-page":"5.12","article-title":"Effects of dietary copper and sulfur amino acids on copper homeostasis and selected indices of copper status in men","author":"Milne","year":"1991"},{"key":"10.1093\/ajcn\/67.5.1041S_bib20","first-page":"73","article-title":"High dietary fructose affects plasma cholesterol concentrations and signs of short-term copper deprivation in men.","volume":"46","author":"Nielsen","year":"1992","journal-title":"Proc N D Acad Sci"},{"key":"10.1093\/ajcn\/67.5.1041S_bib21","series-title":"Trace elements in man and animals. TEMA-8","first-page":"370","article-title":"Effect of high dietary fructose on Cu homeostasis and status indicators in men during Cu deprivation.","author":"Milne","year":"1993"},{"key":"10.1093\/ajcn\/67.5.1041S_bib22","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/ajcn\/63.3.358","article-title":"Effects of a diet low in copper on copper-status indicators in postmenopausal women.","volume":"63","author":"Milne","year":"1996","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib23","first-page":"A820","article-title":"Low dietary copper and the copper status of young men.","volume":"8","author":"Turnlund","year":"1994","journal-title":"FASEB J"},{"key":"10.1093\/ajcn\/67.5.1041S_bib24","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1093\/clinchem\/39.5.883","article-title":"Assessment of copper status: effect of age and gender on reference ranges in healthy adults.","volume":"39","author":"Milne","year":"1993","journal-title":"Clin Chem"},{"key":"10.1093\/ajcn\/67.5.1041S_bib25","series-title":"Trace elements in man and animals. TEMA-6","first-page":"451","article-title":"Comparison of indices of copper status in men and women fed diets marginal in copper.","author":"Milne","year":"1988"},{"key":"10.1093\/ajcn\/67.5.1041S_bib26","first-page":"842","article-title":"Long term variability of selected parameters related to Zn, Cu, and Fe nutriture.","volume":"41","author":"Milne","year":"1985","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib27","first-page":"55","article-title":"Short-term intraindividual variability in plasma trace mineral concentrations.","volume":"2","author":"Solomons","year":"1986","journal-title":"J Micronutr Anal"},{"key":"10.1093\/ajcn\/67.5.1041S_bib28","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/clinchem\/35.3.369","article-title":"Short-term and long-term variability of indices related to nutritional status. I. Ca, Cu, Fe, Mg, and Zn.","volume":"35","author":"Gallagher","year":"1989","journal-title":"Clin Chem"},{"key":"10.1093\/ajcn\/67.5.1041S_bib29","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1093\/jn\/95.3.429","article-title":"Effect of supplementary copper on blood and liver copper-containing fractions in rats.","volume":"95","author":"Milne","year":"1968","journal-title":"J Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib30","doi-asserted-by":"crossref","first-page":"214","DOI":"10.3181\/00379727-203-43594","article-title":"Comparative responses of rats to different copper intakes and modes of supplementation.","volume":"203","author":"Klevay","year":"1993","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1093\/ajcn\/67.5.1041S_bib31","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/S0271-5317(05)80330-6","article-title":"Effects of age, smoking, drinking, exercise and estrogen use on indices of copper status in healthy adults.","volume":"10","author":"Fisher","year":"1990","journal-title":"Nutr Res"},{"key":"10.1093\/ajcn\/67.5.1041S_bib32","first-page":"237","article-title":"Boron enhances and mimics some effects of estrogen therapy in postmenopausal women.","volume":"5","author":"Nielsen","year":"1992","journal-title":"J Trace Elem Exp Med"},{"key":"10.1093\/ajcn\/67.5.1041S_bib33","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0009-8981(93)90112-H","article-title":"Trace element concentrations (Cu, Zn, Fe) in sera from patients with dilated cardiomyopathy.","volume":"214","author":"Oster","year":"1993","journal-title":"Clin Chim Acta"},{"key":"10.1093\/ajcn\/67.5.1041S_bib34","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/clinchem\/21.4.578","article-title":"Influence of myocardial infarction on serum manganese, copper, and zinc concentrations.","volume":"21","author":"Versieck","year":"1975","journal-title":"Clin Chem"},{"key":"10.1093\/ajcn\/67.5.1041S_bib35","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/BF02990200","article-title":"Serum zinc and copper in myocardial infarction with particular reference to prognosis.","volume":"31","author":"Jain","year":"1991","journal-title":"Biol Trace Elem Res"},{"key":"10.1093\/ajcn\/67.5.1041S_bib36","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF02795618","article-title":"Cardiac copper, magnesium, and zinc in recent and old myocardial infarction.","volume":"10","author":"Zama","year":"1986","journal-title":"Biol Trace Elem Res"},{"key":"10.1093\/ajcn\/67.5.1041S_bib37","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1093\/oxfordjournals.aje.a116370","article-title":"Serum copper and the risk of acute myocardial infarction: a prospective study of men in eastern Finland.","volume":"135","author":"Klevay","year":"1992","journal-title":"Am J Epidemiol"},{"key":"10.1093\/ajcn\/67.5.1041S_bib38","first-page":"281","article-title":"Dietary sulfur amino acids, and genetic make-up or interindividual variation affect the response of men to copper depletion.","volume":"3","author":"Nielsen","year":"1990","journal-title":"J Trace Elem Exp Med"},{"key":"10.1093\/ajcn\/67.5.1041S_bib39","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1093\/ajcn\/51.6.1093","article-title":"Physical training and copper, iron, and zinc status of swimmers.","volume":"51","author":"Lukaski","year":"1990","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib40","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/0003-2697(89)90192-9","article-title":"An assay for superoxide dismutase in mammalian tissue homogenates.","volume":"179","author":"Spitz","year":"1989","journal-title":"Anal Biochem"},{"key":"10.1093\/ajcn\/67.5.1041S_bib41","series-title":"Trace elements in human and animal nutrition. 3rd ed.","author":"Underwood","year":"1971"},{"key":"10.1093\/ajcn\/67.5.1041S_bib42","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1399-0004.1977.tb01294.x","article-title":"Menkes' kinky hair syndrome: is it a treatable disorder?","volume":"11","author":"Garnica","year":"1977","journal-title":"Clin Genet"},{"key":"10.1093\/ajcn\/67.5.1041S_bib43","article-title":"Effect of dietary copper on platelet volume and cytochromec oxidase in platelets.","volume":"3","author":"Ralston","year":"1989","journal-title":"FASEB J"},{"key":"10.1093\/ajcn\/67.5.1041S_bib44","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/S0271-5317(05)80739-0","article-title":"Platelet cytochromec oxidase is an indicator of copper status in rats.","volume":"13","author":"Johnson","year":"1993","journal-title":"Nutr Res"},{"key":"10.1093\/ajcn\/67.5.1041S_bib45","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1093\/jn\/122.suppl_3.636","article-title":"Copper as a cofactor and regulator of copper-zinc superoxide dismutase.","volume":"122","author":"Harris","year":"1992","journal-title":"J Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib46","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1093\/jn\/118.7.859","article-title":"Role of copper in regulation and accumulation of superoxide dismutase and metallothionein in rat liver.","volume":"118","author":"Cheung","year":"1988","journal-title":"J Nutr"},{"key":"10.1093\/ajcn\/67.5.1041S_bib47","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1042\/bj2480663","article-title":"Regulation of aortic CuZn-superoxide dismutase with copper.","volume":"248","author":"Dameron","year":"1987","journal-title":"Biochem J"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523183237?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523183237?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/67\/5\/1041S\/24038031\/1041s.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T23:23:20Z","timestamp":1718321000000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523183237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,5]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1998,5]]}},"alternative-id":["S0002916523183237"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/67.5.1041s","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[1998,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Copper intake and assessment of copper status","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/67.5.1041S","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1998 American Society for Nutrition. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}