{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T12:18:43Z","timestamp":1790165923255,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1999,2,1]],"date-time":"1999-02-01T00:00:00Z","timestamp":917827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T00:00:00Z","timestamp":1676419200000},"content-version":"vor","delay-in-days":8780,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1999,2]]},"DOI":"10.1093\/ajcn\/69.2.331","type":"journal-article","created":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T20:13:48Z","timestamp":1519157628000},"page":"331-337","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Influence of the metabolic sequelae of liver cirrhosis on nutritional intake"],"prefix":"10.1016","volume":"69","author":[{"given":"Rosemary A","family":"Richardson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H Isobel","family":"Davidson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Hinds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Cowan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Rae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O James","family":"Garden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/69.2.331_bib1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1093\/ajcn\/44.3.323","article-title":"Energy expenditure in chronic alcoholics with and without liver disease","volume":"44","author":"Jhangiani","year":"1986","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1177\/0148607189013002124","article-title":"Resting energy expenditure in patients with alcoholic hepatitis","volume":"13","author":"John","year":"1989","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib3","first-page":"464","article-title":"Are patients with primary biliary cirrhosis hypermetabolic? A comparison between patients before and after liver transplantation and controls","volume":"14","author":"Green","year":"1991","journal-title":"Hepatology"},{"key":"10.1093\/ajcn\/69.2.331_bib4","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1002\/hep.1840150507","article-title":"Energy expenditure and substrate oxidation in patients with cirrhosis: the impact of cause, clinical staging and nutritional state","volume":"15","author":"Muller","year":"1992","journal-title":"Hepatology"},{"key":"10.1093\/ajcn\/69.2.331_bib5","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0899-9007(97)83001-8","article-title":"Influence of liver failure, ascites and energy expenditure on the response to oral nutrition in alcoholic liver cirrhosis","volume":"13","author":"Campillo","year":"1997","journal-title":"Nutrition"},{"key":"10.1093\/ajcn\/69.2.331_bib6","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1440-1746.1993.tb01180.x","article-title":"Pathogenesis and assessment of malnutrition in liver disease","volume":"8","author":"Crawford","year":"1993","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1093\/ajcn\/69.2.331_bib7","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1177\/0148607195019004258","article-title":"Protein energy malnutrition in severe alcoholic hepatitis: diagnosis and response to treatment","volume":"19","author":"Mendenhall","year":"1995","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib8","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1093\/ajcn\/63.4.602","article-title":"Malnutrition in alcoholic and virus-related cirrhosis","volume":"63","author":"Caregaro","year":"1996","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0261-5614(06)80007-5","article-title":"Nutritional assessment in primary biliary cirrhosis: the effect of disease severity","volume":"14","author":"Wicks","year":"1995","journal-title":"Clin Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib10","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1002\/hep.510230516","article-title":"Does malnutrition affect survival in cirrhosis?","volume":"23","author":"Merli","year":"1996","journal-title":"Hepatology"},{"key":"10.1093\/ajcn\/69.2.331_bib11","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0261-5614(94)90092-2","article-title":"Are patients with liver cirrhosis hypermetabolic?","volume":"13","author":"Muller","year":"1994","journal-title":"Clin Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib12","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1093\/ajcn\/60.2.269","article-title":"Evaluation of nutritional status by using anthropometry in adults with alcoholic and nonalcoholic liver disease","volume":"60","author":"Thuluvath","year":"1994","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib13","first-page":"R106","article-title":"Evidence for hepatic involvement in control of ad libitum food intake in rats","volume":"247","author":"Friedman","year":"1984","journal-title":"Am J Physiol"},{"key":"10.1093\/ajcn\/69.2.331_bib14","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/0031-9384(91)90352-O","article-title":"Hepatic and intestinal handling of metabolites during feeding in rats","volume":"49","author":"Langhans","year":"1991","journal-title":"Physiol Behav"},{"key":"10.1093\/ajcn\/69.2.331_bib15","first-page":"35","article-title":"Metabolic regulation of food intake","volume":"1","author":"Scharrer","year":"1993","journal-title":"Proc Soc Nutr Physiol"},{"key":"10.1093\/ajcn\/69.2.331_bib16","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/j.1749-6632.1969.tb12914.x","article-title":"Afferent impulse discharges from glucoreceptors in the liver of the guinea pig","volume":"157","author":"Niijima","year":"1982","journal-title":"Ann N Y Acad Sci"},{"key":"10.1093\/ajcn\/69.2.331_bib17","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/hep.1840050115","article-title":"Insulin action in cirrhosis","volume":"5","author":"Taylor","year":"1985","journal-title":"Hepatology"},{"key":"10.1093\/ajcn\/69.2.331_bib18","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1056\/NEJM198712033172301","article-title":"Long-term treatment of alcoholic liver disease with propylthiouracil","volume":"317","author":"Orrego","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/69.2.331_bib19","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/bjs.1800600817","article-title":"Transection of the oesophagus for bleeding oesophageal varices","volume":"60","author":"Pugh","year":"1973","journal-title":"Br J Surg"},{"key":"10.1093\/ajcn\/69.2.331_bib20","article-title":"The assessment of the nutritional status of the community","volume":"53","author":"Jeliffe","year":"1996","journal-title":"World Health Organ Monogr Ser"},{"key":"10.1093\/ajcn\/69.2.331_bib21","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1042\/cs0860479","article-title":"Evaluation of multi-frequency bio-impedance analysis for the assessment of extracellular and total body water in surgical patients","volume":"86","author":"Hannan","year":"1994","journal-title":"Clin Sci"},{"key":"10.1093\/ajcn\/69.2.331_bib22","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/bjs.1800790516","article-title":"Bioelectrical impedance analysis in the measurement of the body composition of surgical patients","volume":"79","author":"Fearon","year":"1992","journal-title":"Br J Surg"},{"key":"10.1093\/ajcn\/69.2.331_bib23","series-title":"Surgical nutrition.","first-page":"3","article-title":"Body composition","author":"Shizgal","year":"1983"},{"key":"10.1093\/ajcn\/69.2.331_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.1949.sp004363","article-title":"New methods for calculating metabolic rate with special reference to protein metabolism","volume":"109","author":"de Weir","year":"1949","journal-title":"J Physiol"},{"key":"10.1093\/ajcn\/69.2.331_bib25","first-page":"E62","article-title":"Nutritional influences on lipogenesis and thermogenesis after a carbohydrate meal","volume":"246","author":"Acheson","year":"1984","journal-title":"Am J Physiol"},{"key":"10.1093\/ajcn\/69.2.331_bib26","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/ajcn\/40.2.255","article-title":"Improved models for determination of body fat by in vivo neutron activation","volume":"40","author":"Cohn","year":"1984","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib27","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/BF00210228","article-title":"Protein-calorie malnutrition in liver cirrhosis","volume":"70","author":"Lautz","year":"1992","journal-title":"Clin Invest"},{"key":"10.1093\/ajcn\/69.2.331_bib28","first-page":"54","article-title":"Resting and post-prandial energy expenditure and fuel utilization in patients with compensated cirrhosis and control subjects","volume":"11","author":"Levine","year":"1989","journal-title":"Clin Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib29","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1055\/s-0029-1211331","article-title":"Glucose metabolism and liver cirrhosis","volume":"103","author":"Nolte","year":"1995","journal-title":"Clin Endocrinol"},{"key":"10.1093\/ajcn\/69.2.331_bib30","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1210\/jcem-73-4-777","article-title":"Decreased serum growth hormone binding protein in patients with liver cirrhosis","volume":"73","author":"Baruch","year":"1991","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1093\/ajcn\/69.2.331_bib31","first-page":"G206","article-title":"Role of spontaneous portal-systemic shunting in hyperinsulinism of cirrhosis","volume":"247","author":"Bosch","year":"1984","journal-title":"Am J Physiol"},{"key":"10.1093\/ajcn\/69.2.331_bib32","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2337\/diab.27.1.S201","article-title":"C-peptide and insulin in liver disease","volume":"27","author":"Johnston","year":"1978","journal-title":"Diabetes"},{"key":"10.1093\/ajcn\/69.2.331_bib33","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0149-7634(95)00045-G","article-title":"Role of the liver in the metabolic control of eating: what we know\u2014and what we do not know","volume":"20","author":"Langhans","year":"1996","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1093\/ajcn\/69.2.331_bib34","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0261-5614(97)80101-X","article-title":"Is the dietary treatment of hepatic encephalopathy in UK hospitals appropriate? A survey of current practice","volume":"16","author":"Soulsby","year":"1997","journal-title":"Clin Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib35","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1079\/BJN19930068","article-title":"Nutritional assessment and adequacy of dietary intake in hospitalized patients with alcoholic liver cirrhosis","volume":"69","author":"Nielsen","year":"1993","journal-title":"Br J Nutr"},{"key":"10.1093\/ajcn\/69.2.331_bib36","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0361-9230(86)90099-7","article-title":"Integrated metabolic control of food intake","volume":"17","author":"Friedman","year":"1986","journal-title":"Brain Res Bull"},{"key":"10.1093\/ajcn\/69.2.331_bib37","first-page":"161","article-title":"Determinants of postprandial appetite sensations: macronutrient intake and glucose metabolism","volume":"20","author":"Raben","year":"1996","journal-title":"Int J Obes"},{"key":"10.1093\/ajcn\/69.2.331_bib38","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/hep.510250327","article-title":"Identification of high and low risk patients before liver transplantation: a prospective cohort study of nutritional and metabolic parameters in 150 patients","volume":"25","author":"Selberg","year":"1997","journal-title":"Hepatology"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916522042770?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916522042770?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/69\/2\/331\/23935275\/331.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T02:12:27Z","timestamp":1686276747000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916522042770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,2]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,2]]}},"alternative-id":["S0002916522042770"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/69.2.331","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[1999,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of the metabolic sequelae of liver cirrhosis on nutritional intake","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/69.2.331","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1999 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}