{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T20:25:23Z","timestamp":1785270323728,"version":"3.55.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,7,1]],"date-time":"2001-07-01T00:00:00Z","timestamp":993945600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T00:00:00Z","timestamp":1677456000000},"content-version":"vor","delay-in-days":7911,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[2001,7]]},"DOI":"10.1093\/ajcn\/74.1.50","type":"journal-article","created":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T20:45:16Z","timestamp":1519159516000},"page":"50-56","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":143,"title":["Effects of a high-dose concentrate of n\u22123 fatty acids or corn oil introduced early after an acute myocardial infarction on serum triacylglycerol and HDL cholesterol"],"prefix":"10.1016","volume":"74","author":[{"given":"Dennis WT","family":"Nilsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grethe","family":"Albrektsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knud","family":"Landmark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solfrid","family":"Moen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torbj\u00f8rn","family":"Aarsland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leik","family":"Woie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/74.1.50_bib1","first-page":"3","article-title":"Fish oil and ischemic heart disease","volume":"3","author":"Bang","year":"1987","journal-title":"Compr Ther"},{"key":"10.1093\/ajcn\/74.1.50_bib2","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1056\/NEJM198803033180905","article-title":"Cardiovascular effects of n\u22123 fatty acids","volume":"318","author":"Leaf","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.2165\/00003495-199447030-00003","article-title":"Omega-3 fatty acids: current status in cardiovascular medicine","volume":"47","author":"Schmidt","year":"1994","journal-title":"Drugs"},{"key":"10.1093\/ajcn\/74.1.50_bib4","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1093\/ajcn\/65.4.1083","article-title":"Fish consumption, fish oil, lipids, and coronary heart disease","volume":"65","author":"Stone","year":"1997","journal-title":"Am J Clin Nutr"},{"issue":"suppl","key":"10.1093\/ajcn\/74.1.50_bib5","doi-asserted-by":"crossref","first-page":"1020S","DOI":"10.1093\/ajcn\/66.4.1020S","article-title":"Are fish oils beneficial in the prevention and treatment of coronary artery disease?","volume":"66","author":"Connor","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/74.1.50_bib6","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/S0002-9149(99)80276-8","article-title":"Effects of dietary fish oil on ventricular premature complexes","volume":"76","author":"Sellmayer","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1093\/ajcn\/74.1.50_bib7","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1056\/NEJM199003223221202","article-title":"Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the Troms\u00f8 study","volume":"322","author":"B\u00f8naa","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib8","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1056\/NEJM198505093121902","article-title":"Reduction of plasma lipids, lipoproteins, and apoproteins by dietary fish oils in patients with hypertriglyceridemia","volume":"312","author":"Phillipson","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib9","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0022-2275(20)38310-3","article-title":"Fish oils and plasma lipid and lipoprotein metabolism in humans: a critical review","volume":"30","author":"Harris","year":"1989","journal-title":"J Lipid Res"},{"key":"10.1093\/ajcn\/74.1.50_bib10","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1365-2796.1995.tb01173.x","article-title":"Improvement of serum lipids and blood pressure during intervention with n\u22123 fatty acids was not associated with changes in insulin levels in subjects with combined hyperlipidaemia","volume":"237","author":"Grundt","year":"1995","journal-title":"J Intern Med"},{"key":"10.1093\/ajcn\/74.1.50_bib11","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/ajcn\/61.4.831","article-title":"Long-term metabolic effects of n\u22123 polyunsaturated fatty acids in patients with coronary artery disease","volume":"61","author":"Eritsland","year":"1995","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/74.1.50_bib12","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1161\/01.CIR.97.11.1027","article-title":"Triglyceride. The forgotten risk factor","volume":"97","author":"Gotto","year":"1998","journal-title":"Circulation"},{"key":"10.1093\/ajcn\/74.1.50_bib13","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1161\/01.CIR.97.11.1029","article-title":"Triglyceride concentration and ischemic heart disease. An eight-year follow-up in the Copenhagen male study","volume":"97","author":"Jeppesen","year":"1998","journal-title":"Circulation"},{"key":"10.1093\/ajcn\/74.1.50_bib14","series-title":"Advanced nutrition research. Vol 3.","first-page":"1","article-title":"Lipid metabolism and ischemic heart disease in Greenland Eskimos","author":"Bang","year":"1980"},{"key":"10.1093\/ajcn\/74.1.50_bib15","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1056\/NEJM198505093121901","article-title":"The inverse relation between fish consumption and 20-year mortality from coronary heart disease","volume":"312","author":"Kromhout","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib16","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1056\/NEJM198509263131311","article-title":"Fish consumption and mortality from coronary heart disease","volume":"313","author":"Shekelle","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib17","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3181\/00379727-200-43413","article-title":"Epidemiological evidence of relationships between dietary polyunsaturated fatty acids and mortality in the Multiple Risk Factor Intervention Trial","volume":"200","author":"Dolecek","year":"1992","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1093\/ajcn\/74.1.50_bib18","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1093\/ije\/24.2.340","article-title":"The protective effect of a small amount of fish in coronary heart disease mortality in an elderly population","volume":"24","author":"Kromhout","year":"1995","journal-title":"Int J Epidemiol"},{"key":"10.1093\/ajcn\/74.1.50_bib19","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1056\/NEJM199704103361502","article-title":"Fish consumption and the 30-year risk of fatal myocardial infarction","volume":"336","author":"Daviglus","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib20","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1161\/01.CIR.94.5.952","article-title":"Fish intake may limit the increase in risk of coronary heart disease morbidity and mortality among heavy smokers; The Honolulu Heart Program","volume":"94","author":"Rodriquez","year":"1996","journal-title":"Circulation"},{"key":"10.1093\/ajcn\/74.1.50_bib21","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1056\/NEJM198509263131311","article-title":"Fish consumption and mortality from coronary heart disease","volume":"313","author":"Vollset","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib22","first-page":"821","article-title":"Fish consumption and mortality from coronary heart disease","volume":"313","author":"Curb","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib23","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJM199504133321501","article-title":"Dietary intake of marine n\u22123 fatty acids, fish intake, and the risk of coronary disease among men","volume":"332","author":"Ascherio","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1093\/ajcn\/74.1.50_bib24","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1001\/jama.279.1.23","article-title":"Fish consumption and risk of sudden cardiac death","volume":"279","author":"Albert","year":"1998","journal-title":"JAMA"},{"key":"10.1093\/ajcn\/74.1.50_bib25","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0735-1097(94)00370-6","article-title":"A prospective study of plasma fish oil levels and incidence of myocardial infarction in U.S. male physicians","volume":"25","author":"Guallar","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1093\/ajcn\/74.1.50_bib26","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/jama.1995.03530170043030","article-title":"Dietary intake and cell membrane levels of long-chain n\u22123 polyunsaturated fatty acids and the risk of primary cardiac arrest","volume":"274","author":"Siscovick","year":"1995","journal-title":"JAMA"},{"key":"10.1093\/ajcn\/74.1.50_bib27","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0140-6736(89)90828-3","article-title":"Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and Reinfarction Trial (DART)","volume":"2","author":"Burr","year":"1989","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/74.1.50_bib28","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0140-6736(99)07072-5","article-title":"Dietary supplementation with n\u22123 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial","volume":"354","year":"1999","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/74.1.50_bib29","series-title":"Myocardial infarction community registers.","year":"1976"},{"key":"10.1093\/ajcn\/74.1.50_bib30","series-title":"BMDP statistical software, release 7, module 5V. Repeated measure models with structured and unstructured covariance matrices.","author":"Dixon","year":"1993"},{"key":"10.1093\/ajcn\/74.1.50_bib31","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/S0140-6736(94)92580-1","article-title":"Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease","volume":"343","author":"de Lorgeril","year":"1994","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/74.1.50_bib32","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1023\/A:1007757724505","article-title":"Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival-4","volume":"11","author":"Singh","year":"1997","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1093\/ajcn\/74.1.50_bib33","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/00043798-199604000-00014","article-title":"Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies","volume":"3","author":"Hokanson","year":"1996","journal-title":"J Cardiovasc Risk"},{"key":"10.1093\/ajcn\/74.1.50_bib34","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1161\/01.CIR.85.1.37","article-title":"Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study: implications for treatment","volume":"85","author":"Manninen","year":"1992","journal-title":"Circulation"},{"key":"10.1093\/ajcn\/74.1.50_bib35","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1093\/ajcn\/51.1.53","article-title":"Reversal of the arrhythmogenic effects of long-term saturated fatty acid intake by dietary n\u22123 and n\u22126 polyunsaturated fatty acids","volume":"51","author":"McLennan","year":"1990","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/74.1.50_bib36","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/ajcn\/57.2.207","article-title":"Relative effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on cardiac arrhythmias in rats","volume":"57","author":"McLennan","year":"1993","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/ajcn\/74.1.50_bib37","first-page":"353","article-title":"Differential effects of various oil diets on the risk of cardiac arrhythmias in rats","volume":"1","author":"Insensee","year":"1994","journal-title":"J Cardiovasc Risk"},{"key":"10.1093\/ajcn\/74.1.50_bib38","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0014-2999(95)00701-6","article-title":"Protective effects of free polyunsaturated fatty acids on arrhythmias induced by lysophophatidylcholine or palmitoylcarnitine in neonatal rat cardiac myocytes","volume":"297","author":"Kang","year":"1996","journal-title":"Eur J Pharmacol"},{"key":"10.1093\/ajcn\/74.1.50_bib39","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1161\/01.ATV.19.7.1681","article-title":"The effect of supplementation with omega-3 fatty acids on soluble markers of endothelial function in patients with coronary heart disease","volume":"19","author":"Johansen","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1093\/ajcn\/74.1.50_bib40","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1055\/s-0037-1614525","article-title":"Procoagulant activity and cytokine expression in whole blood cultures from patients with atherosclerosis supplemented with omega-3 fatty acids","volume":"81","author":"Seljeflot","year":"1999","journal-title":"Thromb Haemost"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523062664?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523062664?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/74\/1\/50\/23964442\/50.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T02:27:20Z","timestamp":1686277640000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523062664"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["S0002916523062664"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/74.1.50","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[2001,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of a high-dose concentrate of n\u22123 fatty acids or corn oil introduced early after an acute myocardial infarction on serum triacylglycerol and HDL cholesterol","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/74.1.50","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}