{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T06:51:29Z","timestamp":1792306289341,"version":"4.4.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Peritoneal mesothelial cysts have been reported under various terms, including benign cystic mesothelioma, usually in the form of case reports\/series, whereas extraperitoneal cases are rarely reported. Our objective was to report the detailed characteristics of cystic lesions of the serosal cavities.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We retrospectively examined the clinicopathologic findings of a series of mesothelial cystic lesions (n = 79).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Most cases (n = 68, 86%) concerned the peritoneum, whereas 11 (14%) concerned the pericardium. No pleural cases were found. A total of 51 (64.5%) lesions were solitary, whereas 28 (35.5%) were multiple. Peritoneal lesions harbored a plump eosinophilic mesothelium and a loose connective stroma, whereas pericardial lesions showed a cuboidal\/flattened mesothelium, collagenous stroma, intense inflammation, and other tissue types, like adipose and muscle tissue. Solitary peritoneal lesions are usually extrapelvic and found in older patients incidentally during other surgeries, whereas multiple lesions are found in younger patients and usually in the pelvis. The lesions show a benign clinical course with rare recurrences but no malignant transformation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Most mesothelial cysts are peritoneal and rarely pericardial. Peritoneal cysts differ from pericardial cysts. Peritoneal solitary lesions differ from multiple lesions, also suggesting their pathogenetic differences.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajcp\/aqaa189","type":"journal-article","created":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T11:21:03Z","timestamp":1599218463000},"page":"853-862","source":"Crossref","is-referenced-by-count":24,"title":["Mesothelial Cysts"],"prefix":"10.1093","volume":"155","author":[{"given":"Georgia","family":"Karpathiou","sequence":"first","affiliation":[{"name":"Pathology Department, University Hospital of Saint-Etienne, Saint-Etienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois","family":"Casteillo","sequence":"additional","affiliation":[{"name":"Pathology Department, University Hospital of Saint-Etienne, Saint-Etienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maroa","family":"Dridi","sequence":"additional","affiliation":[{"name":"Pathology Department, University Hospital of Saint-Etienne, Saint-Etienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Peoc\u2019h","sequence":"additional","affiliation":[{"name":"Pathology Department, University Hospital of Saint-Etienne, Saint-Etienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,12,1]]},"reference":[{"key":"2021051816390625600_CIT0001","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.pathol.2019.01.007","article-title":"Non-specific pleuritis: pathological patterns in benign pleuritis","volume":"51","author":"Karpathiou","year":"2019","journal-title":"Pathology."},{"key":"2021051816390625600_CIT0002","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.pathol.2016.08.017","article-title":"Mediastinal cyst of m\u00fcllerian origin: evidence for developmental endosalpingiosis","volume":"49","author":"Karpathiou","year":"2017","journal-title":"Pathology."},{"key":"2021051816390625600_CIT0003","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.rmed.2015.05.014","article-title":"Pleural neoplastic pathology","volume":"109","author":"Karpathiou","year":"2015","journal-title":"Respir Med."},{"key":"2021051816390625600_CIT0004","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/crj.12982","article-title":"Pleura revisited: from histology and pathophysiology to pathology and molecular biology","volume":"13","author":"Karpathiou","year":"2019","journal-title":"Clin Respir J."},{"key":"2021051816390625600_CIT0005","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.athoracsur.2018.04.073","article-title":"Pericardial and pleural metastases: clinical, histologic, and molecular differences","volume":"106","author":"Karpathiou","year":"2018","journal-title":"Ann Thorac Surg."},{"key":"2021051816390625600_CIT0006","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1002\/1097-0142(19890915)64:6<1336::AID-CNCR2820640628>3.0.CO;2-X","article-title":"Multilocular peritoneal inclusion cysts (so-called cystic mesotheliomas)","volume":"64","author":"Ross","year":"1989","journal-title":"Cancer."},{"key":"2021051816390625600_CIT0007","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1097\/00000478-198810000-00001","article-title":"Multicystic mesothelioma: an analysis of pathologic findings and biologic behavior in 37 cases","volume":"12","author":"Weiss","year":"1988","journal-title":"Am J Surg Pathol."},{"key":"2021051816390625600_CIT0008","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1007\/s00404-018-4728-2","article-title":"Benign multicystic mesothelioma and peritoneal inclusion cysts: are they the same clinical and histopathological entities? 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