{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T20:33:06Z","timestamp":1772137986853,"version":"3.50.1"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,1,5]],"date-time":"2021-01-05T00:00:00Z","timestamp":1609804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Departments of Laboratory Medicine and Division of Hematology and Oncology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Serologic testing for antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in potential donors of coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) may not be performed until after blood donation. A hospital-based recruitment program for CCP may be an efficient way to identify potential donors prospectively<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients who recovered from known or suspected COVID-19 were identified and recruited through medical record searches and public appeals in March and April 2020. Participants were screened with a modified donor history questionnaire and, if eligible, were asked for consent and tested for SARS-CoV-2 antibodies (IgG and IgM). Participants positive for SARS-CoV-2 IgG were referred for CCP collection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 179 patients screened, 128 completed serologic testing and 89 were referred for CCP donation. IgG antibodies to SARS-CoV-2 were detected in 23 of 51 participants with suspected COVID-19 and 66 of 77 participants with self-reported COVID-19 confirmed by polymerase chain reaction (PCR). The anti\u2013SARS-CoV-2 IgG level met the US Food and Drug Administration criteria for \u201chigh-titer\u201d CCP in 39% of participants confirmed by PCR, as measured by the Ortho VITROS IgG assay. A wide range of SARS-CoV-2 IgG levels were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A hospital-based CCP donor recruitment program can prospectively identify potential CCP donors. Variability in SARS-CoV-2 IgG levels has implications for the selection of CCP units for transfusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ajcp\/aqaa268","type":"journal-article","created":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T07:19:56Z","timestamp":1606979996000},"page":"515-521","source":"Crossref","is-referenced-by-count":1,"title":["Hospital-Based Donor Recruitment and Predonation Serologic Testing for COVID-19 Convalescent Plasma"],"prefix":"10.1093","volume":"155","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4013-0419","authenticated-orcid":false,"given":"Joanna","family":"Balcerek","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelin","family":"Trejo","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kendall","family":"Levine","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Couey","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoe V","family":"Kornberg","sequence":"additional","affiliation":[{"name":"School of Medicine, University of California San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camille","family":"Rogine","sequence":"additional","affiliation":[{"name":"School of Medicine, University of California San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Young","sequence":"additional","affiliation":[{"name":"School of Medicine, University of California San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P Jonathan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Medicine, University of California San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian R","family":"Shy","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan E","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Bakhtary","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3630-4941","authenticated-orcid":false,"given":"Terence","family":"Friedlander","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kara L","family":"Lynch","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caryn","family":"Bern","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan H","family":"Esensten","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,1,5]]},"reference":[{"key":"2021031518091973400_CIT0001","doi-asserted-by":"crossref","first-page":"4791","DOI":"10.1172\/JCI140200","article-title":"Early safety indicators of COVID-19 convalescent plasma in 5000 patients","volume":"130","author":"Joyner","year":"2020","journal-title":"J Clinical 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