{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T11:18:19Z","timestamp":1788866299465,"version":"build-2803163510"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Lobular capillary hemangioma (LCH) rarely involves the gastrointestinal (GI) tract. This study describes clinicopathologic features of LCH in a cohort of GI cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We defined lobular capillary hemangioma as \u201ca proliferation of capillary-sized blood vessels arranged at least focally in a lobular configuration,\u201d searched departmental archives for cases, and recorded clinicopathologic findings.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We identified 34 GI tract LCHs from 16 men and 10 women; 4 patients had multiple lesions. Mean age was 64 years. Cases arose in the esophagus (n\u2009=\u20097), stomach (n\u2009=\u20093), small bowel (n\u2009=\u20097), and colorectum (n\u2009=\u200917). Twelve patients had anemia or rectal bleeding. No patients had a known genetic syndrome. The lesions manifested as mucosal polyps, with median size of 1.3 cm. Microscopically, 20 lesions were ulcerated, and most involved the mucosa, with 9 extending into the submucosa. Vessel dilation was present in 27 patients, endothelial hobnailing in 13, hemorrhage in 13, and focal reactive stromal atypia in 2. Follow-up information was available for 10 patients, none of whom developed same-site recurrence. Six of the 26 cases (23%) were extradepartmental consultations, including 2 of the multifocal cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Gastrointestinal tract LCHs often arise as colorectal polyps. They are typically small but can reach a few centimeters in size and can be multifocal.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajcp\/aqad064","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T15:11:21Z","timestamp":1686237081000},"page":"411-416","source":"Crossref","is-referenced-by-count":3,"title":["Lobular capillary hemangioma (pyogenic granuloma) of the gastrointestinal tract: Clinicopathologic analysis of 34 cases"],"prefix":"10.1093","volume":"160","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1231-4117","authenticated-orcid":false,"given":"Adam L","family":"Booth","sequence":"first","affiliation":[{"name":"Department of Pathology, Northwestern University , Chicago, IL , US"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lysandra","family":"Voltaggio","sequence":"additional","affiliation":[{"name":"Department of Pathology, Johns Hopkins Medicine , Baltimore, MD , 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