{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:40:02Z","timestamp":1734050402181,"version":"3.30.2"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This quality improvement study conducted at the Kansas City VA Medical Center in Kansas City, Missouri, investigated the Sysmex DI-60 Integrated Slide Processing System\u2019s ability to improve hematology turnaround times when integrated into daily practices. It further addressed potential patient care factors associated with changes in turnaround times.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Three months of manual and Sysmex DI-60 patient data were examined between May 2022 and February 2023. White blood cell (WBC) ranges, turnaround times, working hours, and study months were analyzed using 2-tailed unpaired t testing and percentage change. The number of specimens in these categories was further analyzed using 2-tailed, 2-sample proportion testing.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>This quality improvement study indicated that the Sysmex DI-60 system produced a statistically significant reduction in turnaround times overall and for various ranges of WBCs plus work shifts. The most statistically significant improvement in turnaround times occurred for WBC concentrations less than 2.0 \u00d7 103\/\u00b5L and concentrations within the reference range. In addition, the off shifts experienced a notable improvement in turnaround times.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The Sysmex DI-60 system substantially decreases turnaround times for differentials, thus potentially benefiting patient care by providing prompt results. It is possible that reducing turnaround times could expedite emergency department admissions and discharges as well as enhance care for the oncology department\u2019s patients. It could also lead to more timely results for patients with false-positive flags by the Sysmex analyzer, which may also help with clinician decision-making.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajcp\/aqae084","type":"journal-article","created":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T22:38:26Z","timestamp":1718663906000},"page":"648-654","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating the Sysmex DI-60 Integrated Slide Processing System\u2019s impact on hematology differential turnaround times and patient care: Real-world implementation experience in a large Veterans Affairs hospital"],"prefix":"10.1093","volume":"162","author":[{"given":"Cory R","family":"Lundgren","sequence":"first","affiliation":[{"name":"Clinical Laboratory Science, University of Kansas Medical Center , Kansas City, KS ,","place":["US"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,7,19]]},"reference":[{"author":"DI-60 Integrated Slide Processing System","journal-title":"Sysmex","key":"2024121300182177100_CIT0001"},{"key":"2024121300182177100_CIT0002","article-title":"Low white blood cell count and cancer","author":"Roberts","year":"2021","journal-title":"MedlinePlus."},{"issue":"1","key":"2024121300182177100_CIT0003","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1111\/j.1751-553X.2007.01002.x","article-title":"Can automated blood film analysis replace the manual differential? An evaluation of the CellaVision DM96 automated image analysis system","volume":"31","author":"Briggs","year":"2009","journal-title":"Int J Lab Hematol."},{"issue":"4","key":"2024121300182177100_CIT0004","doi-asserted-by":"publisher","first-page":"398","DOI":"10.3343\/alm.2022.42.4.398","article-title":"Digital morphology analyzer Sysmex DI-60 vs. manual counting for white blood cell differentials in leukopenic samples: a comparative assessment of risk and turnaround time","volume":"42","author":"Nam","year":"2022","journal-title":"Ann Lab Med."},{"year":"2019","author":"Integrated slide processing system DI-60","journal-title":"Sysmex","key":"2024121300182177100_CIT0005"},{"issue":"9","key":"2024121300182177100_CIT0006","doi-asserted-by":"publisher","first-page":"e28824","DOI":"10.7759\/cureus.28824","article-title":"Turnaround time: an efficacy measure for medical laboratories","volume":"14","author":"Dawande","year":"2022","journal-title":"Cureus"},{"issue":"1","key":"2024121300182177100_CIT0007","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1111\/acem.12565","article-title":"The effect of laboratory testing on emergency department length of stay: a multihospital longitudinal study applying a cross-classified random-effect modeling approach","volume":"22","author":"Li","year":"2015","journal-title":"Acad Emerg Med."}],"container-title":["American Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajcp\/article-pdf\/162\/6\/648\/60882770\/aqae084.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajcp\/article-pdf\/162\/6\/648\/60882770\/aqae084.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:18:28Z","timestamp":1734049108000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajcp\/article\/162\/6\/648\/7717460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,19]]},"references-count":7,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,7,19]]},"published-print":{"date-parts":[[2024,12,2]]}},"URL":"https:\/\/doi.org\/10.1093\/ajcp\/aqae084","relation":{},"ISSN":["0002-9173","1943-7722"],"issn-type":[{"type":"print","value":"0002-9173"},{"type":"electronic","value":"1943-7722"}],"subject":[],"published-other":{"date-parts":[[2024,12]]},"published":{"date-parts":[[2024,7,19]]}}}