{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T01:15:34Z","timestamp":1778894134176,"version":"3.51.4"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T00:00:00Z","timestamp":1563148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The 2017 Workshop of the Society for Hematopathology\/European Association for Hematopathology aimed to review premalignant clonal hematopoietic proliferations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The workshop panel reviewed 27 cases of clonal proliferations of indeterminate significance or potential (18 myeloid, nine lymphoid) and rendered consensus diagnoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Immunophenotyping and genetic studies on peripheral blood, bone marrow, and lymph node samples have led to the incidental detection of small clonal populations in asymptomatic individuals. These premalignant clonal myeloid and lymphoid proliferations include monoclonal gammopathy of uncertain significance, monoclonal B-cell lymphocytosis, in situ follicular neoplasia, in situ mantle cell neoplasia, clonal hematopoiesis of indeterminate potential, and clonal cytopenia of undetermined significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Current diagnostic criteria for the diagnoses of premalignant clonal hematopoietic proliferations are reviewed and discussed in the context of the cases presented at the workshop.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ajcp\/aqz079","type":"journal-article","created":{"date-parts":[[2019,5,16]],"date-time":"2019-05-16T11:16:11Z","timestamp":1558005371000},"page":"347-358","source":"Crossref","is-referenced-by-count":4,"title":["Premalignant Clonal Hematopoietic Proliferations"],"prefix":"10.1093","volume":"152","author":[{"given":"Valentina","family":"Nardi","sequence":"first","affiliation":[{"name":"Department of Pathology, Massachusetts General Hospital, Boston"},{"name":"Harvard Medical School, Boston, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank C","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of California Los Angeles"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert P","family":"Hasserjian","sequence":"additional","affiliation":[{"name":"Department of Pathology, Massachusetts General Hospital, Boston"},{"name":"Harvard Medical School, Boston, 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