{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T08:50:47Z","timestamp":1745052647127},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To determine how often end-stage kidney disease (ESKD) is implicated as a cause of death (COD) at autopsy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We searched our autopsy database (2007-2017) using queries \u201cend-stage renal disease,\u201d \u201cend-stage kidney disease,\u201d \u201cESRD,\u201d \u201cchronic renal disease,\u201d and \u201cchronic kidney disease.\u201d Final diagnosis and summaries were reviewed to determine if ESKD was appropriately correlated with the COD. Cases in which the COD was unrelated to kidney function were excluded.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Eighty-five patients with a history of ESKD and histologic confirmation thereof were identified. Their CODs were cardiovascular (36%), infection\/sepsis (41%), pulmonary (6%), gastrointestinal\/hepatic (2%), central nervous system (3%), other systemic disease (7%), and unspecified (5%). ESKD was implicated as a contributing COD in 24 (28%) cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>ESKD is often overlooked at autopsy, particularly in patients with cardiovascular or infectious disease. Accurate documentation of ESKD contributing to mortality is important for education, counseling, record maintenance, and directing research efforts.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajcp\/aqz211","type":"journal-article","created":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T20:11:12Z","timestamp":1576786272000},"page":"772-775","source":"Crossref","is-referenced-by-count":2,"title":["End-Stage Kidney Disease Is Overlooked as a Proximate Cause of Death at Autopsy"],"prefix":"10.1093","volume":"153","author":[{"given":"Meredith A","family":"Reynolds","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Chicago Medical Center, Chicago, IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kammi J","family":"Henriksen","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Chicago Medical Center, Chicago, IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Chicago Medical Center, Chicago, IL"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,1,29]]},"reference":[{"key":"2020050514074672800_CIT0001","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization","volume":"1296-1305","author":"Go","year":"2004","journal-title":"N Engl J Med"},{"key":"2020050514074672800_CIT0002","article-title":"Deaths: leading causes for 2016. 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