{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T22:51:24Z","timestamp":1785365484363,"version":"3.55.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T00:00:00Z","timestamp":1681862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Estimates of the prevalence of long-term symptoms of coronavirus disease 2019 (COVID-19), referred to as long COVID, vary widely. This retrospective cohort study describes the incidence of long COVID symptoms 12\u201320 weeks postdiagnosis in a US ambulatory care setting and identifies potential risk factors. We identified patients with and without a diagnosis of or positive test for COVID-19 between January 1, 2020, and March 13, 2022, in the Veradigm (Veradigm LLC, Chicago, Illinois) electronic health record database. We captured data on patient demographic characteristics, clinical characteristics, and COVID-19 comorbidity in the 12-month baseline period. We compared long COVID symptoms between matched cases and controls 12\u201320 weeks after the index date (COVID-19 diagnosis date (cases) or median visit date (controls)). Multivariable logistic regression was used to examine associations between baseline COVID-19 comorbid conditions and long COVID symptoms. Among 916,894 patients with COVID-19, 14.8% had at least 1 long COVID symptom in the 12\u201320 weeks postindex as compared with 2.9% of patients without documented COVID-19. Commonly reported symptoms were joint stiffness (4.5%), cough (3.0%), and fatigue (2.7%). Among patients with COVID-19, the adjusted odds of long COVID symptoms were significantly higher among patients with a baseline COVID-19 comorbid condition (odds ratio = 1.91, 95% confidence interval: 1.88, 1.95). In particular, prior diagnosis of cognitive disorder, transient ischemic attack, hypertension, or obesity was associated with higher odds of long COVID symptoms.<\/jats:p>","DOI":"10.1093\/aje\/kwad095","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T05:42:40Z","timestamp":1681882960000},"page":"1350-1357","source":"Crossref","is-referenced-by-count":25,"title":["Long COVID Incidence in a Large US Ambulatory Electronic Health Record System"],"prefix":"10.1093","volume":"192","author":[{"given":"Robert","family":"Sedgley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessamine","family":"Winer-Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Machaon","family":"Bonafede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,4,19]]},"reference":[{"issue":"5","key":"2023080423141185500_ref1","doi-asserted-by":"crossref","first-page":"e1089","DOI":"10.1093\/cid\/ciaa1750","article-title":"Comprehensive health assessment 3 months after recovery from acute coronavirus disease 2019 (COVID-19)","volume":"73","author":"Borst","year":"2021","journal-title":"Clin Infect Dis."},{"issue":"47","key":"2023080423141185500_ref2","doi-asserted-by":"crossref","DOI":"10.3346\/jkms.2020.35.e418","article-title":"Three-month follow-up study of survivors of coronavirus disease 2019 after discharge","volume":"35","author":"Liang","year":"2020","journal-title":"J Korean Med Sci."},{"issue":"4","key":"2023080423141185500_ref3","doi-asserted-by":"crossref","first-page":"00542","DOI":"10.1183\/23120541.00542-2020","article-title":"Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome?","volume":"6","author":"Go\u00ebrtz","year":"2020","journal-title":"ERJ Open Res."},{"issue":"1","key":"2023080423141185500_ref4","doi-asserted-by":"crossref","first-page":"16144","DOI":"10.1038\/s41598-021-95565-8","article-title":"More than 50 long-term effects of COVID-19: a systematic review and meta-analysis","volume":"11","author":"Lopez-Leon","year":"2021","journal-title":"Sci Rep."},{"issue":"1","key":"2023080423141185500_ref5","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1186\/s13054-021-03794-0","article-title":"The impact of COVID-19 critical illness on new disability, 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