{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:12:47Z","timestamp":1787008367398,"version":"build-2736575974"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Many persons with immunological tests indicating Mycobacterium tuberculosis infection, such as tuberculin skin tests or interferon-\u03b3 release assays, are at risk of progression to tuberculosis disease. Persons whose tests revert to negative may no longer be at such risk. Therefore, identifying the rate of test reversion, potentially indicating cure of M. tuberculosis infection, is an important area of investigation. In their accompanying article (Am J Epidemiol. 2023;192(12):1937\u20131943), Schwalb et al. extract data on test reversion from prechemotherapy literature and construct a model to predict the rate of reversion, and thus the likely cure of infection. Unfortunately, the incompleteness of the historical data and the use of imprecise definitions of test positivity and reversion lead to substantial misclassification and limit the usefulness of the model. Better definitions and improved tests will be needed in order to develop a clear picture of this aspect of the natural history of tuberculosis.<\/jats:p>","DOI":"10.1093\/aje\/kwad125","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T08:24:53Z","timestamp":1684916693000},"page":"1944-1946","source":"Crossref","is-referenced-by-count":4,"title":["Invited Commentary: The Winding Road to Identifying the Annual Rate of Tuberculosis Infection"],"prefix":"10.1093","volume":"192","author":[{"given":"C Robert","family":"Horsburgh, Jr.","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,5,23]]},"reference":[{"issue":"9","key":"2023120112352912800_ref1","doi-asserted-by":"crossref","first-page":"e271","DOI":"10.1016\/S1473-3099(22)00153-0","article-title":"Are we underestimating the annual risk of infection with Mycobacterium tuberculosis in high-burden settings?","volume":"22","author":"Dowdy","year":"2022","journal-title":"Lancet Infect Dis."},{"issue":"3","key":"2023120112352912800_ref2","doi-asserted-by":"crossref","first-page":"e965","DOI":"10.1093\/cid\/ciac451","article-title":"Contribution of reinfection to annual rate of tuberculosis infection (ARI) and incidence of TB disease","volume":"76","author":"Horsburgh","year":"2023","journal-title":"Clin Infect Dis."},{"issue":"11","key":"2023120112352912800_ref3","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.5588\/ijtld.11.0015","article-title":"Dual skin tests with Mycobacterium avium sensitin and PPD to detect misdiagnosis of latent tuberculosis infection","volume":"15","author":"Larson","year":"2011","journal-title":"Int J Tuberc Lung Dis."},{"issue":"2","key":"2023120112352912800_ref4","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/oxfordjournals.aje.a121593","article-title":"The prognosis of a positive tuberculin reaction in childhood and adolescence","volume":"99","author":"Comstock","year":"1974","journal-title":"Am J Epidemiol."},{"issue":"1","key":"2023120112352912800_ref5","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1164\/ajrccm.159.1.9801120","article-title":"Interpretation of repeated tuberculin tests. 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