{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:07:29Z","timestamp":1790309249770,"version":"4.1.0"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA228147"],"award-info":[{"award-number":["R01CA228147"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA179977"],"award-info":[{"award-number":["R01CA179977"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Air pollution and noise exposure may synergistically contribute to increased cardiometabolic disorders; however, few studies have examined this potential interaction or considered exposures beyond residential location. The combined impact of dynamic air pollution and transportation noise on cardiometabolic disorders in San Diego County was investigated. Using data from the Community of Mine Study (2014-2017), 602 ethnically diverse participants were assessed for obesity, dyslipidemia, hypertension, and metabolic syndrome (MetS), using anthropometric measurements and biomarkers from blood samples. Time-weighted measures of exposure to fine particulate matter, nitrogen dioxide (NO2), and road and aircraft noise were calculated using global positioning system mobility data and kernel density estimation. Generalized estimating equation models were used to analyze associations. Interactions were assessed on the multiplicative and additive scales using relative excess risk due to interaction (RERI). We found that air pollution and noise interact to affect metabolic disorders on both multiplicative and additive scales. The effect of noise on obesity and MetS was higher when air pollution level was higher. The RERIs of aircraft noise and NO2 on obesity and MetS were 0.13 (95% CI, 0.03-0.22) and 0.13 (95% CI, 0.02-0.25), respectively. These findings suggest aircraft noise and air pollution may have synergistic effects on obesity and MetS.<\/jats:p>\n                  <jats:p>This article is part of a Special Collection on Environmental Epidemiology.<\/jats:p>","DOI":"10.1093\/aje\/kwae117","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T18:36:25Z","timestamp":1719254185000},"page":"1515-1523","source":"Crossref","is-referenced-by-count":2,"title":["Combined impact of dynamic air pollution and transportation noise on cardiometabolic disorders in San Diego County"],"prefix":"10.1093","volume":"194","author":[{"given":"Blanche","family":"Berneron","sequence":"first","affiliation":[{"name":"Scripps Institution of Oceanography , University of California San Diego, San Diego, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiue-An","family":"Yang","sequence":"additional","affiliation":[{"name":"Beckman Research Institute, City of Hope Population Sciences, , Duarte, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta M","family":"Jankowska","sequence":"additional","affiliation":[{"name":"Beckman Research Institute, City of Hope Population Sciences, , Duarte, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarik","family":"Benmarhnia","sequence":"additional","affiliation":[{"name":"Scripps Institution of Oceanography , University of California San Diego, San Diego, CA,","place":["USA"]},{"name":"Irset (Institut de recherche en sant\u00e9, environnement et travail) Universit\u00e9 de Rennes, Inserm, EHESP, , MR_S 1085, Rennes,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6925-1217","authenticated-orcid":false,"given":"No\u00e9mie","family":"Letellier","sequence":"additional","affiliation":[{"name":"Scripps Institution of Oceanography , University of California San Diego, San Diego, CA,","place":["USA"]},{"name":"Irset (Institut de recherche en sant\u00e9, environnement et travail) Universit\u00e9 de Rennes, Inserm, EHESP, , MR_S 1085, Rennes,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"issue":"10119","key":"2026041217383000100_ref1","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1016\/S0140-6736(17)32345-0","article-title":"The Lancet Commission on pollution and health","volume":"391","author":"Landrigan","year":"2018","journal-title":"Lancet"},{"key":"2026041217383000100_ref2","author":"American College of Cardiology","year":"2023"},{"issue":"14","key":"2026041217383000100_ref3","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1016\/j.jacc.2010.05.034","article-title":"The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis","volume":"56","author":"Mottillo","year":"2010","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"2026041217383000100_ref4","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.114.001548","article-title":"Accumulation of metabolic cardiovascular risk factors in black and white young adults over 20 years","volume":"4","author":"Paynter","year":"2015","journal-title":"J Am Heart Assoc"},{"issue":"11","key":"2026041217383000100_ref5","doi-asserted-by":"publisher","first-page":"2130","DOI":"10.1097\/HJH.0000000000000342","article-title":"Effect of exposure to PM2.5 on blood pressure: a systematic review and meta-analysis","volume":"32","author":"Liang","year":"2014","journal-title":"J Hypertens"},{"issue":"9","key":"2026041217383000100_ref6","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1093\/aje\/kwr424","article-title":"Association of long-term exposure to community noise and traffic-related air pollution with coronary heart disease mortality","volume":"175","author":"Gan","year":"2012","journal-title":"Am J Epidemiol"},{"issue":"3","key":"2026041217383000100_ref7","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.envres.2017.03.019","article-title":"Long-term residential road traffic noise and NO2 exposure in relation to risk of incident myocardial infarction - 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