{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T18:46:48Z","timestamp":1781808408821,"version":"3.54.5"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T00:00:00Z","timestamp":1723161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UL1TR002553"],"award-info":[{"award-number":["UL1TR002553"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["K01140146"],"award-info":[{"award-number":["K01140146"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>There is a profound need to identify modifiable risk factors to screen and prevent pancreatic cancer. Air pollution, including fine particulate matter (PM2.5), is increasingly recognized as a risk factor for cancer. We conducted a case-control study using data from the electronic health record (EHR) of Duke University Health System, 15-year residential history, NASA satellite fine particulate matter (PM2.5), and neighborhood socioeconomic data. Using deterministic and probabilistic linkage algorithms, we linked residential history and EHR data to quantify long-term PM2.5 exposure. Logistic regression models quantified the association between a 1 interquartile range (IQR) increase in PM2.5 concentration and pancreatic cancer risk. The study included 203 cases and 5027 controls (median age of 59\u00a0years, 62% female, 26% Black). Individuals with pancreatic cancer had higher average annual exposure (9.4\u00a0\u03bcg\/m3) as compared to an IQR increase in average annual PM2.5, which was associated with greater odds of pancreatic cancer (odds ratio\u00a0=\u00a01.20; 95% CI, 1.00-1.44). These findings highlight the link between elevated PM2.5 exposure and increased pancreatic cancer risk. They may inform screening strategies for high-risk populations and guide air pollution policies to mitigate exposure.<\/jats:p>\n               <jats:p>This article is part of a Special Collection on Environmental Epidemiology.<\/jats:p>","DOI":"10.1093\/aje\/kwae271","type":"journal-article","created":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T03:15:31Z","timestamp":1723259731000},"page":"730-737","source":"Crossref","is-referenced-by-count":8,"title":["The association between long-term PM2.5 exposure and risk for pancreatic cancer: an application of social informatics"],"prefix":"10.1093","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9937-5560","authenticated-orcid":false,"given":"Nrupen A","family":"Bhavsar","sequence":"first","affiliation":[{"name":"Department of Surgery, School of Medicine, Duke University , Durham, NC ,","place":["United States"]},{"name":"Department of Biostatistics and Bioinformatics, School of Medicine, Duke University , Durham, NC 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