{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T23:57:45Z","timestamp":1763683065165,"version":"3.45.0"},"reference-count":60,"publisher":"Oxford University Press (OUP)","issue":"11","funder":[{"name":"Prevention at the University of North Carolina at Chapel Hill","award":["U01DD001231"],"award-info":[{"award-number":["U01DD001231"]}]},{"name":"Centers for Disease Control and Prevention (CDC) to the North Carolina Center for Birth Defects Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Orofacial clefts (OFC) are a common birth defect with few known risk factors (eg, smoking). Maternal diet is associated with birth defects, though the relationship with OFC is less clear as studies typically only investigate single nutrients. We assessed the association between periconceptional maternal diet and OFC in the United States, using the National Birth Defects Prevention Study (1997-2011), including 3649 cases (2480 cleft lip with\/without palate [CL\/P] and 1169 cleft palate [CP]) and 10\u2009584 controls (infants without a birth defect). Using latent class analysis, we derived dietary patterns based on relative consumption of self-reported food items via food frequency data. We used logistic regression to estimate adjusted odds ratios (aORs) and 95% CIs for the effect of dietary patterns on OFC. Four patterns were identified: Prudent (reference), Western, Low-Calorie Western, and Mexican. The Western diet had increased odds of CL\/P (aOR: 1.3 [95% CI, 1.2-1.5]) and CP (aOR: 1.2 [95% CI, 1.1-1.4]). Low-Calorie Western (CL\/P aOR: 1.2 [95% CI, 1.0-1.4]; CP aOR: 1.0 [95% CI, 0.9-1.2]) and Mexican diets (CL\/P aOR: 1.1 [95% CI, 0.9-1.3]; CP aOR: 0.8 [95% CI, 0.6-1.1]) had a weaker or null association. Findings underscore the importance of further investigation into the effect of periconceptional diet on OFC occurrence.<\/jats:p>","DOI":"10.1093\/aje\/kwaf102","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T08:05:09Z","timestamp":1746777909000},"page":"3217-3228","source":"Crossref","is-referenced-by-count":0,"title":["Association between maternal periconceptional dietary patterns and occurrence of orofacial clefts"],"prefix":"10.1093","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2922-7046","authenticated-orcid":false,"given":"Erin G","family":"Sley","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, NC ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1600-3700","authenticated-orcid":false,"given":"Tania A","family":"Desrosiers","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, NC ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3226-6140","authenticated-orcid":false,"given":"Daniela","family":"Sotres-Alvarez","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, NC ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6310-5924","authenticated-orcid":false,"given":"Suzan L","family":"Carmichael","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Stanford University School of Medicine , Stanford, CA ,","place":["United States"]},{"name":"Department of Obstetrics and Gynecology, Stanford University School of Medicine , Stanford, CA ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6270-8237","authenticated-orcid":false,"given":"Joanna","family":"Maselko","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, NC ,","place":["United States"]},{"name":"Carolina Population Center, University of North Carolina at Chapel Hill , Chapel Hill, NC ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9302-2641","authenticated-orcid":false,"given":"Mollie E","family":"Wood","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, NC ,","place":["United 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