{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T01:50:03Z","timestamp":1785894603432,"version":"3.56.0"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"8","funder":[{"name":"CDC cooperative agreements","award":["PA #96043, PA #02081, FOA #DD09-001, FOA #DD13-003, NOFO #DD18-001, and NOFO #DD23-001"],"award-info":[{"award-number":["PA #96043, PA #02081, FOA #DD09-001, FOA #DD13-003, NOFO #DD18-001, and NOFO #DD23-001"]}]},{"name":"the Centers for Disease Control and Prevention (CDC) to the North Carolina Center for Birth Defects Research and Prevention at the University of North Carolina at Chapel Hill","award":["U01DD001308"],"award-info":[{"award-number":["U01DD001308"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We examined the role of neighborhood-level socioeconomic position (nSEP) in 1- and 5-year survival among children with critical congenital heart defects (CCHDs). Children with CCHDs in the National Birth Defects Prevention Study (1999-2011) were grouped into univentricular and biventricular defects and linked to vital records for 1- and 5-year mortality. The Neighborhood Deprivation Index (NDI) was used to classify census-tract nSEP (low [referent], moderate, high deprivation) using maternal periconceptional address. Kaplan\u2013Meier survival curves and log-rank tests were used to evaluate survival differences. Cox proportional hazards regression models were used to estimate crude and adjusted hazard ratios and 95% confidence intervals, adjusting for birth years, maternal sociodemographic factors, and residential mobility. Among 2459 children with CCHDs, 1 year survival curves differed by neighborhood deprivation. Survival was lowest among children of mothers living in high- vs low-deprivation neighborhoods. In crude analyses, high deprivation was associated with higher 1-year mortality (all CCHDs: 1.58 [1.17, 2.13]; univentricular CCHDs: 1.50 [0.99, 2.26]; biventricular CCHDs: 1.64 [1.02, 2.64]). After adjustment, estimates were generally attenuated and less precise. Five-year survival showed similar trends. Further research could inform strategies to address the structural, environmental, and\/or physiological factors associated with a potential reduced survival among children with CCHDs born to mothers in socioeconomically deprived areas.<\/jats:p>","DOI":"10.1093\/aje\/kwag078","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T11:41:35Z","timestamp":1776253295000},"page":"2200-2211","source":"Crossref","is-referenced-by-count":0,"title":["Neighborhood-level socioeconomic position and mortality among children born with critical congenital heart defects"],"prefix":"10.1093","volume":"195","author":[{"given":"Sanjida J","family":"Mowla","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, NC ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantel 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,","place":["United States"]},{"name":"Centers for Disease Control and Prevention , \u00a0 , Atlanta, GA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon Pruitt","family":"Evans","sequence":"additional","affiliation":[{"name":"Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities , \u00a0 , Atlanta, GA ,","place":["United States"]},{"name":"Centers for Disease Control and Prevention , \u00a0 , Atlanta, GA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah C","family":"Fisher","sequence":"additional","affiliation":[{"name":"Birth Defects Registry , \u00a0 , Albany, NY ,","place":["United States"]},{"name":"New York State Department of Health , \u00a0 , Albany, NY ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A","family":"Romitti","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, College of Public Health, University of Iowa , Iowa City, IA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzan L","family":"Carmichael","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Stanford University School of Medicine , Stanford, CA ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J","family":"Lupo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine , Houston, TX ,","place":["United States"]},{"name":"Texas Children's Cancer Center, Texas Children's Hospital , Houston, TX ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Marie","family":"Darling","sequence":"additional","affiliation":[{"name":"Massachusetts Center for Birth Defects Research and Prevention, 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