{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T02:13:22Z","timestamp":1788401602999,"version":"build-2803163510"},"reference-count":57,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Project of Jiangsu Province Engineering Research Center of Molecular Target Therapy and Companion Diagnostics in Oncology"},{"name":"Wu Jieping Medical Foundation\u2014Clinical Research Special Grant"},{"name":"Suzhou Applied Basic Research Program (Medical and Health Care)\u2014Science and Technology Innovation Project"},{"name":"Outstanding Young Talents Project in Health of Qilu; the Youth Talent Training Program from Qingdao Medical College of Qingdao University"},{"name":"Taishan Scholar Project"},{"name":"Key Project of Shandong Provincial Natural Science Foundation"},{"name":"Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions, China; the Shandong Provincial Postdoctoral Foundation Project"},{"name":"Nuclear Energy Development Project, China"},{"name":"Suzhou Clinical Trial Institution Capacity Enhancement Project"},{"name":"Suzhou Medical and Industrial Integration Collaborative Innovation Research Project"},{"name":"Social Development\u2014Clinical Frontier Technology Project of the Science and Technology Department of Jiangsu Province"},{"name":"Scientific Research Foundation for Talented Scholars in Soochow University, China"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Neurodegenerative diseases (NDDs) represent a growing cause of mortality and disability among aging populations worldwide. However, the relationship between cumulative, multidomain environmental exposures, and NDD mortality remains poorly characterized. This study aimed to examine the association between comprehensive environmental quality and NDD mortality in the United States. We used the environmental quality index (EQI) from 2000 to 2005 to characterize cumulative environmental exposure. Associations between EQI quintiles and NDD mortality, including dementia, Parkinson\u2019s disease (PD), amyotrophic lateral sclerosis, and Huntington\u2019s disease, were examined using Bayesian interval-censored mixed-effects models. During 2006-2020, among 3.66 million NDD deaths, poorer environmental quality (Q5 vs Q1) was associated with mortality rate differences of 24.72 (95% credible intervals [CrI]: 22.43, 27.06) per 100\u2009000 at 5-year lag, 26.74 (95% CrI: 24.34, 29.21) at 10-year lag, and 22.74 (95% CrI: 20.49, 25.13) at 15-year lag. Within each lag period, a clear dose\u2013response pattern was consistently observed across EQI quintiles. Furthermore, associations were most pronounced for the air quality, followed by sociodemographic disadvantage. In addition, demographic and geographic heterogeneity was observed across sex, race, census regions, urbanicity, climate zone, and county economic type. These findings underscore the need for integrated, place-based environmental health policies targeting neurodegeneration prevention.<\/jats:p>","DOI":"10.1093\/aje\/kwag114","type":"journal-article","created":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T11:44:17Z","timestamp":1779536657000},"page":"2440-2449","source":"Crossref","is-referenced-by-count":0,"title":["Cumulative environmental burden and neurodegenerative disease mortality: a national ecological study in the United States"],"prefix":"10.1093","volume":"195","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5559-0580","authenticated-orcid":false,"given":"Guoli","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Epidemiology, School of Public Health, Suzhou Medical College of Soochow University , Suzhou, Jiangsu, 215123 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2831-3133","authenticated-orcid":false,"given":"Yu","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Geography and Ocean Science, Nanjing University , Nanjing, 210003 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2058-5427","authenticated-orcid":false,"given":"Junlan","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Oncology and Hematology, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University , Suzhou, Jiangsu, 215008 ,","place":["China"]},{"name":"Suzhou Research Center of Medical School, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University , Suzhou, Jiangsu, 215008 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5418-3354","authenticated-orcid":false,"given":"Chao","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Neurology, Yantai Yuhuangding Hospital, Qingdao University , Yantai, Shandong, 264000 ,","place":["China"]},{"name":"Shandong Provincial Key Laboratory of Neuroimmune Interaction and Regulation, Yantai Yuhuangding Hospital , Yantai, Shandong, 264000 ,","place":["China"]},{"name":"Yantai Municipal Key Medical and Health Laboratory (Interdisciplinary Brain Science and Geriatric Health Laboratory), Yantai Yuhuangding Hospital , Yantai, Shandong, 264000 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4201-5932","authenticated-orcid":false,"given":"Konglan","family":"Shao","sequence":"additional","affiliation":[{"name":"School of Geography and Ocean Science, Nanjing University , Nanjing, 210003 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4933-5851","authenticated-orcid":false,"given":"Xiaochen","family":"Shu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health, Suzhou Medical College of Soochow University , Suzhou, Jiangsu, 215123 ,","place":["China"]},{"name":"Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-communicable Diseases, Suzhou Medical College of Soochow University , Suzhou, Jiangsu, 215123 ,","place":["China"]},{"name":"MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University , Suzhou, Jiangsu, 215123 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"2026090221215648900_ref1","volume-title":"Neurodegenerative Diseases: Unifying Principles","author":"Cummings","year":"2016"},{"issue":"10440","key":"2026090221215648900_ref2","doi-asserted-by":"publisher","first-page":"2133","DOI":"10.1016\/S0140-6736(24)00757-8","article-title":"Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021","volume":"403","author":"GBD 2021 Diseases and Injuries Collaborators","year":"2024","journal-title":"Lancet"},{"issue":"2","key":"2026090221215648900_ref3","doi-asserted-by":"publisher","first-page":"e105","DOI":"10.1016\/S2468-2667(21)00249-8","article-title":"Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the global burden of disease study 2019","volume":"7","author":"GBD 2019 Dementia Forecasting Collaborators","year":"2022","journal-title":"Lancet Public Health"},{"issue":"5","key":"2026090221215648900_ref4","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1093\/brain\/awab151","article-title":"Preventing neurodegenerative disease","volume":"144","author":"Al-Chalabi","year":"2021","journal-title":"Brain."},{"issue":"1","key":"2026090221215648900_ref5","doi-asserted-by":"publisher","first-page":"53","DOI":"10.31887\/DCNS.2019.21.1\/rperneczky2","article-title":"Dementia prevention and reserve against neurodegenerative disease","volume":"21","author":"Perneczky","year":"2019","journal-title":"Dialogues Clin Neurosci"},{"key":"2026090221215648900_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2022.106550","article-title":"Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: implications for neurodegenerative disease treatment","volume":"186","author":"Kopp","year":"2022","journal-title":"Pharmacol Res"},{"issue":"3","key":"2026090221215648900_ref7","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/s41582-020-00435-y","article-title":"Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?","volume":"17","author":"Leng","year":"2021","journal-title":"Nat Rev Neurol"},{"issue":"6753","key":"2026090221215648900_ref8","doi-asserted-by":"publisher","first-page":"eadx0043","DOI":"10.1126\/science.adx0043","article-title":"Neuroinflammation across neurological diseases","volume":"388","author":"Shi","year":"2025","journal-title":"Science."},{"issue":"11","key":"2026090221215648900_ref9","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/j.tins.2023.08.010","article-title":"Air pollution, glymphatic impairment, and Alzheimer\u2019s disease","volume":"46","author":"Hussain","year":"2023","journal-title":"Trends Neurosci"},{"issue":"4","key":"2026090221215648900_ref10","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.eehl.2024.08.002","article-title":"Adverse outcome pathway for the neurotoxicity of per- and polyfluoroalkyl substances: a systematic review","volume":"3","author":"Li","year":"2024","journal-title":"Eco-Environ Health"},{"key":"2026090221215648900_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116880","article-title":"The role of exosome-shuttled miRNAs in heavy metal-induced peripheral tissues and neuroinflammation in Alzheimer\u2019s disease","volume":"176","author":"Dong","year":"2024","journal-title":"Biomed Pharmacother"},{"issue":"5-6","key":"2026090221215648900_ref12","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1242\/dmm.001180","article-title":"A comprehensive definition for metabolic syndrome","volume":"2","author":"Huang","year":"2009","journal-title":"Dis Model Mech"},{"issue":"13","key":"2026090221215648900_ref13","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.3390\/cells13131144","article-title":"Heavy metal interactions with neuroglia and gut microbiota: implications for Huntington\u2019s disease","volume":"13","author":"Tizabi","year":"2024","journal-title":"Cells."},{"issue":"1","key":"2026090221215648900_ref14","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1146\/annurev-pathmechdis-031521-033828","article-title":"Circadian clocks, daily stress, and neurodegenerative disease","volume":"20","author":"Nyamugenda","year":"2025","journal-title":"Annu Rev Pathol Mech Dis"},{"issue":"3","key":"2026090221215648900_ref15","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.3390\/ijms25031653","article-title":"Stress, allostatic load, and neuroinflammation: implications for racial and socioeconomic health disparities in glaucoma","volume":"25","author":"McDermott","year":"2024","journal-title":"IJMS."},{"issue":"10","key":"2026090221215648900_ref16","doi-asserted-by":"publisher","first-page":"5085","DOI":"10.3390\/ijms25105085","article-title":"Chronic stress-induced neuroinflammation: relevance of rodent models to human disease","volume":"25","author":"White","year":"2024","journal-title":"IJMS."},{"issue":"1","key":"2026090221215648900_ref17","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1007\/s44169-025-00087-3","article-title":"A critical review on sources, environmental occurrence, toxicity, and human exposure of an abundant organophosphate ester tris(2,4-di-tert-butylphenyl) Phosphate","volume":"263","author":"Kang","year":"2025","journal-title":"Rev Environ Contam Toxicol"},{"issue":"4","key":"2026090221215648900_ref18","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1038\/s41370-024-00720-8","article-title":"Environmental public health research at the U.S. Environmental Protection Agency: a blueprint for exposure science in a connected world","volume":"35","author":"Stanek","year":"2025","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"2026090221215648900_ref19","volume-title":"Creating an Overall Environmental Quality Index\u2013Technical Report (2000\u20132005) (Final, 2014)","author":"U.S. EPA","year":"2014"},{"issue":"3","key":"2026090221215648900_ref20","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1289\/EHP119","article-title":"Associations between environmental quality and mortality in the contiguous United States, 2000\u20132005","volume":"125","author":"Jian","year":"2017","journal-title":"Environ Health Perspect"},{"key":"2026090221215648900_ref21","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4613-3961-8","volume-title":"Neuropharmacology and Behavior","author":"Haber","year":"1978"},{"issue":"1","key":"2026090221215648900_ref22","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1111\/nyas.15138","article-title":"The emotion paradox in the aging body and brain","volume":"1536","author":"Mather","year":"2024","journal-title":"Ann N Y Acad Sci"},{"issue":"6505","key":"2026090221215648900_ref23","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1126\/science.aax3338","article-title":"Huntington\u2019s disease alters human neurodevelopment","volume":"369","author":"Barnat","year":"2020","journal-title":"Science."},{"issue":"7","key":"2026090221215648900_ref24","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1016\/S1474-4422(22)00120-X","article-title":"A biological classification of Huntington\u2019s disease: the Integrated Staging System","volume":"21","author":"Tabrizi","year":"2022","journal-title":"Lancet Neurol"},{"issue":"S1","key":"2026090221215648900_ref25","doi-asserted-by":"publisher","first-page":"S277","DOI":"10.2105\/AJPH.2011.300184","article-title":"Data sources for an environmental quality index: availability, quality, and utility","volume":"101","author":"Lobdell","year":"2011","journal-title":"Am J Public Health"},{"issue":"1","key":"2026090221215648900_ref26","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/1476-069X-13-39","article-title":"Construction of an environmental quality index for public health research","volume":"13","author":"Messer","year":"2014","journal-title":"Environ Health"},{"key":"2026090221215648900_ref27","volume-title":"Rural-Urban Continuum Codes (County Level)","author":"USDA","year":"2003"},{"issue":"3","key":"2026090221215648900_ref28","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1127\/0941-2948\/2006\/0130","article-title":"World map of the K\u00f6ppen-Geiger climate classification updated","volume":"15","author":"Kottek","year":"2006","journal-title":"metz."},{"key":"2026090221215648900_ref29","volume-title":"County Typology Codes","author":"Economic Research Service","year":"2025"},{"key":"2026090221215648900_ref30","doi-asserted-by":"publisher","author":"IHME","year":"2014","DOI":"10.6069\/H6ZD-KX77"},{"issue":"9","key":"2026090221215648900_ref31","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1056\/NEJMoa1202753","article-title":"Clinical and biomarker changes in dominantly inherited Alzheimer\u2019s disease","volume":"367","author":"Bateman","year":"2012","journal-title":"N Engl J Med"},{"issue":"6","key":"2026090221215648900_ref32","doi-asserted-by":"publisher","first-page":"595","DOI":"10.15252\/emmm.201606210","article-title":"The amyloid hypothesis of Alzheimer\u2019s disease at 25 years","volume":"8","author":"Selkoe","year":"2016","journal-title":"EMBO Mol Med"},{"key":"2026090221215648900_ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2021.101503","article-title":"Mitochondrial dysfunction, oxidative stress, neuroinflammation, and metabolic alterations in the progression of Alzheimer\u2019s disease: a meta-analysis of in vivo magnetic resonance spectroscopy studies","volume":"72","author":"Song","year":"2021","journal-title":"Ageing Res Rev"},{"issue":"11","key":"2026090221215648900_ref34","doi-asserted-by":"publisher","first-page":"5938","DOI":"10.3390\/ijms23115938","article-title":"An overview of oxidative stress, neuroinflammation, and neurodegenerative diseases","volume":"23","author":"Teleanu","year":"2022","journal-title":"IJMS."},{"issue":"1","key":"2026090221215648900_ref35","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1038\/s41392-023-01486-5","article-title":"Role of neuroinflammation in neurodegeneration development","volume":"8","author":"Zhang","year":"2023","journal-title":"Sig Transduct Target Ther"},{"issue":"11","key":"2026090221215648900_ref36","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1038\/nrneurol.2016.152","article-title":"Advances in markers of prodromal Parkinson disease","volume":"12","author":"Postuma","year":"2016","journal-title":"Nat Rev Neurol"},{"issue":"13","key":"2026090221215648900_ref37","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.1002\/mds.25898","article-title":"Mortality in Parkinson\u2019s disease: a systematic review and meta-analysis","volume":"29","author":"Macleod","year":"2014","journal-title":"Mov Disord"},{"key":"2026090221215648900_ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2020.107523","article-title":"Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders","volume":"210","author":"Costa","year":"2020","journal-title":"Pharmacol Ther"},{"issue":"11","key":"2026090221215648900_ref39","doi-asserted-by":"publisher","first-page":"6847","DOI":"10.1021\/acs.est.1c04706","article-title":"Air pollution, ultrafine particles, and your brain: are combustion nanoparticle emissions and engineered nanoparticles causing preventable fatal neurodegenerative diseases and common neuropsychiatric outcomes?","volume":"56","author":"Calder\u00f3n-Garcidue\u00f1as","year":"2022","journal-title":"Environ Sci Technol"},{"issue":"1","key":"2026090221215648900_ref40","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s12929-022-00799-x","article-title":"The pathogenic effects of particulate matter on neurodegeneration: a review","volume":"29","author":"You","year":"2022","journal-title":"J Biomed Sci"},{"key":"2026090221215648900_ref41","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.neurobiolaging.2022.10.015","article-title":"A framework for concepts of reserve and resilience in aging","volume":"124","author":"Stern","year":"2023","journal-title":"Neurobiol Aging"},{"issue":"1","key":"2026090221215648900_ref42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11910-019-0917-z","article-title":"Defining cognitive reserve and implications for cognitive aging","volume":"19","author":"Pettigrew","year":"2019","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"12","key":"2026090221215648900_ref43","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1016\/j.biopsych.2019.05.024","article-title":"Socioeconomic disparities in chronic physiologic stress are associated with brain structure in children","volume":"86","author":"Merz","year":"2019","journal-title":"Biol Psychiatry"},{"issue":"1","key":"2026090221215648900_ref44","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1186\/s12877-025-06693-z","article-title":"Neighbourhood-built environment and cognitive or social health in older adults with mild cognitive impairment or dementia: an umbrella review","volume":"25","author":"Altona","year":"2025","journal-title":"BMC Geriatr"},{"issue":"12","key":"2026090221215648900_ref45","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.47664","article-title":"Associations of greenness, parks, and blue space with neurodegenerative disease hospitalizations among older US adults","volume":"5","author":"Klompmaker","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"11","key":"2026090221215648900_ref46","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1136\/jech-2023-220675","article-title":"Cumulative exposure to extreme heat and trajectories of cognitive decline among older adults in the USA","volume":"77","author":"Choi","year":"2023","journal-title":"J Epidemiol Community Health"},{"key":"2026090221215648900_ref47","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.172260","article-title":"Prevalence rates of neurodegenerative diseases versus human exposures to heavy metals across the United States","volume":"928","author":"Newell","year":"2024","journal-title":"Sci Total Environ"},{"key":"2026090221215648900_ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2025.118759","article-title":"Environmental aluminum exposure and Alzheimer\u2019s disease risk: evidence from a systematic review and meta-analysis","volume":"302","author":"Soleimani","year":"2025","journal-title":"Ecotoxicol Environ Saf"},{"issue":"1","key":"2026090221215648900_ref49","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s12940-020-00624-8","article-title":"Occupational pesticide exposure and the risk of death in patients with Parkinson\u2019s disease: an observational study in southern brazil","volume":"19","author":"Schneider Medeiros","year":"2020","journal-title":"Environ Health"},{"key":"2026090221215648900_ref50","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.yrtph.2018.05.005","article-title":"Pesticide exposure and risk of Parkinson\u2019s disease: dose-response meta-analysis of observational studies","volume":"96","author":"Yan","year":"2018","journal-title":"Regul Toxicol Pharmacol"},{"issue":"3","key":"2026090221215648900_ref51","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1212\/wnl.53.3.508","article-title":"Gender differences in the relation between comorbidity and mortality of patients with Alzheimer\u2019s disease. Systematic assessment of geriatric drug use via epidemiology (SAGE) study group","volume":"53","author":"Gambassi","year":"1999","journal-title":"Neurology."},{"issue":"10","key":"2026090221215648900_ref52","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1001\/jamaneurol.2025.2236","article-title":"Sex differences in mortality and health care utilization after dementia diagnosis","volume":"82","author":"Lusk","year":"2025","journal-title":"JAMA Neurol"},{"issue":"5","key":"2026090221215648900_ref53","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1093\/gerona\/glab231","article-title":"Racial\/ethnic disparities in Alzheimer\u2019s disease risk: role of exposure to ambient fine particles","volume":"77","author":"Younan","year":"2022","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2026090221215648900_ref54","doi-asserted-by":"publisher","DOI":"10.1016\/j.ssmph.2022.101164","article-title":"Regional variation in U.S. dementia trends from 2000-2012","volume":"19","author":"Ailshire","year":"2022","journal-title":"SSM Popul Health"},{"issue":"7","key":"2026090221215648900_ref55","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1093\/geronb\/gbad045","article-title":"Geographic patterns of dementia in the United States: variation by place of residence, place of birth, and subpopulation","volume":"78","author":"Zacher","year":"2023","journal-title":"J Gerontol B Psychol Sci Soc Sci"},{"issue":"1","key":"2026090221215648900_ref56","doi-asserted-by":"publisher","first-page":"8236","DOI":"10.1038\/s41467-023-44066-5","article-title":"Temperature-related death burden of various neurodegenerative diseases under climate warming: a nationwide modelling study","volume":"14","author":"Yin","year":"2023","journal-title":"Nat Commun"},{"issue":"9","key":"2026090221215648900_ref57","doi-asserted-by":"publisher","first-page":"4204","DOI":"10.1002\/alz.13104","article-title":"Global rural health disparities in Alzheimer\u2019s disease and related dementias: state of the science","volume":"19","author":"Wiese","year":"2023","journal-title":"Alzheimers Dement"}],"container-title":["American Journal of Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/aje\/advance-article-pdf\/doi\/10.1093\/aje\/kwag114\/68381631\/kwag114.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/aje\/article-pdf\/195\/9\/2440\/68381631\/kwag114.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/aje\/article-pdf\/195\/9\/2440\/68381631\/kwag114.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:22:04Z","timestamp":1788398524000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/aje\/article\/195\/9\/2440\/8692703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,25]]},"references-count":57,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,5,25]]},"published-print":{"date-parts":[[2026,9,3]]}},"URL":"https:\/\/doi.org\/10.1093\/aje\/kwag114","relation":{},"ISSN":["0002-9262","1476-6256"],"issn-type":[{"value":"0002-9262","type":"print"},{"value":"1476-6256","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,5,25]]}}}