{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:28:07Z","timestamp":1760956087184,"version":"3.37.3"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T00:00:00Z","timestamp":1612224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>BACKGROUND<\/jats:title>\n                  <jats:p>Atherosclerotic renal artery stenosis is a risk factor for cardiovascular death. Observational studies support the benefit of renal revascularization on outcomes in patients with high-risk clinical manifestations. In this context, we evaluated the factors associated with long-term mortality after renal artery stenting in patients with severe renal artery stenosis, impaired kidney function, and\/or uncontrolled hypertension.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>The medical records of patients undergoing renal artery stenting between 2004 and 2014 were extracted. Blood pressure and creatinine were recorded at baseline, 24 hours poststenting and in the 1-month to 1-year interval that followed revascularization. Long-term follow-up was performed in March 2020.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The cohort consisted of 65 patients. Median follow-up was 120 months. In the first year after stenting, less patients had chronic kidney disease (CKD) class 3b\u20135 as compared with baseline (35.3% vs. 56.9%, P = 0.01). The number of patients with controlled blood pressure after revascularization increased with 69.2% (P &amp;lt; 0.001). Long-term all-cause mortality reached 44.6%. Age (odds ratio (OR) 1.1; 95% confidence interval (CI) 1.0\u20131.2; P = 0.01), male gender (OR 7.9; 95% CI 1.9\u201343.5; P = 0.008), poststenting CKD class 3b\u20135 (OR 5.8; 95% CI 1.5\u201327.9; P = 0.01), and postrevascularization uncontrolled hypertension (OR 8.9; 95% CI 1.7\u201363.5; P = 0.01) were associated with long-term mortality independent of diabetes mellitus and coronary artery disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Improved CKD class and blood pressure were recorded in the first year after renal artery stenting in patients with severe renal artery stenosis and high-risk clinical manifestations. The lack of improvement in kidney function and blood pressure was independently associated with long-term mortality.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajh\/hpab027","type":"journal-article","created":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T20:10:08Z","timestamp":1611778208000},"page":"880-887","source":"Crossref","is-referenced-by-count":10,"title":["Long-Term Mortality After Renal Artery Stenting in Patients With Severe Atherosclerotic Renal Artery Stenosis and High-Risk Clinical Manifestations"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0340-4476","authenticated-orcid":false,"given":"Mihaela Ioana","family":"Dregoesc","sequence":"first","affiliation":[{"name":"\u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Department of Cardiology , Cluj-Napoca , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sorana Daniela","family":"Bolboac\u0103","sequence":"additional","affiliation":[{"name":"\u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Department of Medical Informatics and Biostatistics , Cluj-Napoca , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia Mirela","family":"Dorol\u021ban","sequence":"additional","affiliation":[{"name":"\u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Department of Cardiology , Cluj-Napoca , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihnea","family":"Istrate","sequence":"additional","affiliation":[{"name":"\u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Department of Cardiology , Cluj-Napoca , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u0103d\u0103lin Constantin","family":"Marc","sequence":"additional","affiliation":[{"name":"\u201cNiculae St\u0103ncioiu\u201d Heart Institute, Department of Cardiology , Cluj-Napoca , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian Corneliu","family":"Iancu","sequence":"additional","affiliation":[{"name":"\u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Department of Cardiology , Cluj-Napoca , Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,2,2]]},"reference":[{"key":"2022100812245642100_CIT0001","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/eurheartj\/ehx095","article-title":"2017 ESC Guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society for Vascular Surgery (ESVS): document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries. 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