{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:55:09Z","timestamp":1776214509711,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T00:00:00Z","timestamp":1643068800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["15SDG25740015"],"award-info":[{"award-number":["15SDG25740015"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21 HL 130899"],"award-info":[{"award-number":["R21 HL 130899"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>This study compared aortic pressures estimated using a SphygmoCor XCEL PWA device (ATCOR, Naperville, IL) noninvasively with aortic pressures obtained using pressure catheters during catheterization procedures and analyzed the impact of a linear-fit function on the estimated pressure values.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>One hundred and thirty-six patients scheduled for cardiac catheterization procedure were enrolled in IRB approved studies. Catheterization procedures were performed according to standard-of-care to acquire aortic pressure measurements. Immediately after the catheterization procedure with the pressure catheters removed, while the patients were still in the catheterization laboratory, central aortic pressures were estimated with the SphygmoCor device (using its inbuilt transfer function). The error between measured and estimated aortic pressures was evaluated using Bland\u2013Altman analysis (n = 93). A linear-fit was performed between the measured and estimated pressures, and using the linear equation the error measurements were repeated. A bootstrap analysis was performed to test the generalizability of the linear-fit function. In a subset of cases (n = 13), central aortic pressure values were also obtained using solid-state high-fidelity catheters (Millar, Houston, TX), and the error measurements were repeated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The magnitude of errors between the measured and estimated aortic pressures (mean errors &amp;gt;6.4 mm Hg; mean errors &amp;gt;8.0 mm Hg in the subset) were reduced to less than 1 mm Hg after using the linear-fit function derived in this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>For the population examined in this study, the SphygmoCor data must be used with the linear-fit function to obtain aortic pressures that are comparable to the measurements obtained using pressure catheters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CLINICAL TRIALS REGISTRATION<\/jats:title>\n                    <jats:p>Trial Numbers NCT03243942 and NCT03245255.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ajh\/hpac010","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T15:12:07Z","timestamp":1643037127000},"page":"397-406","source":"Crossref","is-referenced-by-count":11,"title":["Comparing Central Aortic Pressures Obtained Using a SphygmoCor Device to Pressures Obtained Using a Pressure Catheter"],"prefix":"10.1093","volume":"35","author":[{"given":"Cara","family":"Esposito","sequence":"first","affiliation":[{"name":"Department of Radiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscilla","family":"Machado","sequence":"additional","affiliation":[{"name":"Department of Radiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira S","family":"Cohen","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen","family":"Mehrotra","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Savage","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Fischman","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marguerite","family":"Davis","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"II","given":"Nicholas","family":"Ruggiero","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Walinsky","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen E","family":"McDonald","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging and Radiation Sciences, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristopher","family":"Dickie","sequence":"additional","affiliation":[{"name":"Clarius Mobile Health , Vancouver, British Columbia ,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flemming","family":"Forsberg","sequence":"additional","affiliation":[{"name":"Department of Radiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4324-8802","authenticated-orcid":false,"given":"Jaydev K","family":"Dave","sequence":"additional","affiliation":[{"name":"Department of Radiology, Thomas Jefferson University , Philadelphia, Pennsylvania ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,1,25]]},"reference":[{"key":"2026041420042852500_CIT0001","doi-asserted-by":"crossref","first-page":"e254","DOI":"10.1161\/CIR.0000000000000950","article-title":"Heart disease and stroke statistics\u20142021 update: a report from the American Heart Association","volume":"143","author":"Virani","year":"2021","journal-title":"Circulation"},{"key":"2026041420042852500_CIT0002","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2174\/138161209787354203","article-title":"Non-invasive methods and techniques for central blood pressure estimation: procedures, validation, reproducibility and limitations","volume":"15","author":"Papaioannou","year":"2009","journal-title":"Curr Pharm Des"},{"key":"2026041420042852500_CIT0003","doi-asserted-by":"crossref","first-page":"254","DOI":"10.2174\/138161209787354249","article-title":"Is there any additional prognostic value of central blood pressure wave forms beyond peripheral blood pressure?","volume":"15","author":"Sabovic","year":"2009","journal-title":"Curr Pharm Des"},{"key":"2026041420042852500_CIT0004","volume-title":"ANSI\/AAMI SP10:2002 and ANSI\/AAMI SP10:2002\/A1:2003: Manual, Electronic, or Automated Sphygmomanometers","author":"Association for the Advancement of Medical Instrumentation [AAMI]"},{"key":"2026041420042852500_CIT0005","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1161\/01.HYP.21.4.504","article-title":"National standard for measurement of resting and ambulatory blood pressures with automated sphygmomanometers","volume":"21","author":"White","year":"1993","journal-title":"Hypertension"},{"key":"2026041420042852500_CIT0006","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/HJH.0000000000001902","article-title":"Intra-arterial analysis of the best calibration methods to estimate aortic blood pressure","volume":"37","author":"Picone","year":"2019","journal-title":"J Hypertens"},{"key":"2026041420042852500_CIT0007","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/HJH.0000000000001135","article-title":"Invasive validation of a novel brachial cuff-based oscillometric device (SphygmoCor XCEL) for measuring central blood pressure","volume":"35","author":"Shoji","year":"2017","journal-title":"J Hypertens"},{"key":"2026041420042852500_CIT0008","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1093\/eurheartj\/ehw632","article-title":"Validation of non-invasive central blood pressure devices: ARTERY Society task force consensus statement on protocol standardization","volume":"38","author":"Sharman","year":"2017","journal-title":"Eur Heart J"},{"key":"2026041420042852500_CIT0009","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1161\/HYPERTENSIONAHA.120.14916","article-title":"Validation study to determine the accuracy of central blood pressure measurement using the Sphygmocor Xcel cuff device","volume":"76","author":"Schultz","year":"2020","journal-title":"Hypertension"},{"key":"2026041420042852500_CIT0010","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/HJH.0000000000002237","article-title":"Accuracy of fully automated oscillometric central aortic blood pressure measurement techniques","volume":"38","author":"Gotzmann","year":"2020","journal-title":"J Hypertens"},{"key":"2026041420042852500_CIT0011","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/jhh.2013.144","article-title":"Validity and reliability of aortic pulse wave velocity and augmentation index determined by the new cuff-based SphygmoCor Xcel","volume":"28","author":"Hwang","year":"2014","journal-title":"J Hum Hypertens"},{"key":"2026041420042852500_CIT0012","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/ajh\/hpw063","article-title":"Comparison of central blood pressure estimated by a cuff-based device with radial tonometry","volume":"29","author":"Peng","year":"2016","journal-title":"Am J Hypertens"},{"key":"2026041420042852500_CIT0013","first-page":"307","article-title":"Measurement in medicine: the analysis of method comparison studies","volume":"32","author":"Altman","year":"1983","journal-title":"J R Stat Soc Ser D (Stat)"},{"key":"2026041420042852500_CIT0014","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jcmg.2011.08.017","article-title":"Noninvasive LV pressure estimation using subharmonic emissions from microbubbles","volume":"5","author":"Dave","year":"2012","journal-title":"JACC Cardiovasc Imaging"},{"key":"2026041420042852500_CIT0015","doi-asserted-by":"crossref","first-page":"H126","DOI":"10.1152\/ajpheart.00560.2011","article-title":"Subharmonic microbubble emissions for noninvasively tracking right ventricular pressures","volume":"303","author":"Dave","year":"2012","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2026041420042852500_CIT0016","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1016\/j.ultrasmedbio.2017.07.009","article-title":"Non-invasive intra-cardiac pressure measurements using subharmonic-aided pressure estimation: proof of concept in humans","volume":"43","author":"Dave","year":"2017","journal-title":"Ultrasound Med Biol"}],"container-title":["American Journal of Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajh\/advance-article-pdf\/doi\/10.1093\/ajh\/hpac010\/43004501\/hpac010.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajh\/article-pdf\/35\/5\/397\/43630834\/hpac010.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajh\/article-pdf\/35\/5\/397\/43630834\/hpac010.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:07:03Z","timestamp":1776211623000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajh\/article\/35\/5\/397\/6515471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,25]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,1,25]]},"published-print":{"date-parts":[[2022,5,10]]}},"URL":"https:\/\/doi.org\/10.1093\/ajh\/hpac010","relation":{},"ISSN":["0895-7061","1941-7225"],"issn-type":[{"value":"0895-7061","type":"print"},{"value":"1941-7225","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,5,1]]},"published":{"date-parts":[[2022,1,25]]}}}