{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T14:56:46Z","timestamp":1777561006503,"version":"3.51.4"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T00:00:00Z","timestamp":1666310400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Medical Affairs Bureau Ministry of National Defense, Taipei"},{"DOI":"10.13039\/100019813","name":"Hualien Armed Forces General Hospital","doi-asserted-by":"publisher","award":["MND-MAB-110-148"],"award-info":[{"award-number":["MND-MAB-110-148"]}],"id":[{"id":"10.13039\/100019813","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019813","name":"Hualien Armed Forces General Hospital","doi-asserted-by":"publisher","award":["HAFGH-D-110008"],"award-info":[{"award-number":["HAFGH-D-110008"]}],"id":[{"id":"10.13039\/100019813","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Poor oral health evaluated by presence of dental calculus has been associated with hypertension (HTN) among middle- and old-aged adults. However, it is unclear for the association of HTN phenotypes with dental calculus in young adults.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This study examined the association between dental calculus and HTN in 5,345 military personnel, aged 19\u201345 years, without antihypertensive medications therapy in Taiwan from 2018 to 2021. Dental calculus was defined as presence of supragingival calculus in any teeth, except impacted teeth, and third molar. Combined HTN (CHTN) was diagnosed as systolic blood pressure (SBP) \u2265130 mm Hg and diastolic blood pressure (DBP) \u226580 mm Hg. Isolated systolic and diastolic HTN were, respectively, defined as SBP \u2265130 mm Hg only (ISHTN) and DBP \u226580 mm Hg only (IDHTN). Multiple logistic regression with adjustments for sex, age, toxic substance use, anthropometrics, lipid profiles, fasting glucose, and blood leukocyte counts were used to determine the association between dental calculus and HTN phenotypes in young adults.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The prevalence of those with dental calculus, CHTN, ISHTN, and IDHTN was 20.8%, 10.8%, 10.2%, and 7.0%, respectively. The dental calculus was associated a greater possibility with CHTN [odds ratio (OR) and 95% confidence interval: 1.60 (1.31\u20131.95)]. However, the associations of dental calculus with ISHTN and IDHTN were null [OR: 1.05 (0.81\u20131.27) and 1.12 (0.86\u20131.46), respectively].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our findings suggest that among young adults, poor oral health manifested by presence of dental calculus was associated with a greater possibility of CHTN, while not for ISHTN and IDHTN.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajh\/hpac119","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T20:37:38Z","timestamp":1666384658000},"page":"102-108","source":"Crossref","is-referenced-by-count":13,"title":["Association Between Dental Calculus and Hypertension Phenotypes in Highly Fit Adults: CHIEF Oral Health Study"],"prefix":"10.1093","volume":"36","author":[{"given":"Kun-Zhe","family":"Tsai","sequence":"first","affiliation":[{"name":"Department of Medicine, Hualien Armed Forces General Hospital , Hualien City , Taiwan"},{"name":"Department of Stomatology of Periodontology, Mackay Memorial Hospital , Taipei , Taiwan"},{"name":"Department of Dentistry, Tri-Service General Hospital, National Defense Medical Center , Taipei , Taiwan"},{"name":"Graduate Institute of Dental Science, National Defense Medical Center , Taipei , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren-Yeong","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Tri-Service General Hospital, National Defense Medical Center , Taipei , Taiwan"},{"name":"Graduate Institute of Dental Science, National Defense Medical Center , Taipei , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan-Chien","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Tri-Service General Hospital, National Defense Medical Center , Taipei , Taiwan"},{"name":"Graduate Institute of Dental Science, National Defense Medical Center , Taipei , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Lu","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Medicine, Taipei Veterans General Hospital , Taipei , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Chun","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Medicine, National Yang Ming Chiao Tung University , Taipei , Taiwan"},{"name":"Department of Critical Care Medicine, Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuemei","family":"Sui","sequence":"additional","affiliation":[{"name":"Department of Exercise Science, Arnold School of Public Health, University of South Carolina , Columbia, South Carolina , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl 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