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(MAP) and pulse pressure (PP) pressure are associated with short- and long-term mortality in Chinese patients with heart failure with preserved (HFpEF), mid-range (HFmrEF), and reduced (HFrEF) ejection fraction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 2,706 acute decompensated heart failure (HF) patients, we assessed the risk of 30-day, 1-year, and long-term (&amp;gt;1 year) mortality with 1-SD increment in MAP and PP, using multivariable logistic and Cox regression, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During a median follow-up of 4.1 years, 1,341 patients died. The 30-day, 1-year, and long-term mortality were 3.5%, 16.7%, and 39.4%, respectively. A lower MAP was associated with a higher risk of 30-day mortality in women (P = 0.023) and a higher risk of 30-day and 1-year mortality in men (P \u2264 0.006), while higher PP predicted long-term mortality in men (P \u2264 0.014) with no relationship observed in women. In adjusted analyses additionally accounted for PP, 1-SD increment in MAP was associated with 30-day mortality in HFpEF (odds ratio [OR], 0.63; 95% CI, 0.43 to 0.92; P = 0.018), with 1-year mortality in HFmrEF (OR, 0.46; 95% CI, 0.32 to 0.66; P &amp;lt; 0.001) and HFrEF (OR, 0.54; 95% CI, 0.40 to 0.72; P &amp;lt; 0.001). In the adjusted model additionally accounted for MAP, 1-SD increment in PP was associated with long-term mortality in HFpEF (hazard ratio, 1.16; 95% CI, 1.05 to 1.28; P = 0.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A lower MAP was associated with a higher risk of short-term mortality in all HF subtypes, while a higher PP predicted a higher risk of long-term mortality in men and in HFpEF. Our observations highlight the clinical importance of admission blood pressure for risk stratification in HF subtypes.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ajh\/hpac130","type":"journal-article","created":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T23:39:38Z","timestamp":1671147578000},"page":"217-225","source":"Crossref","is-referenced-by-count":5,"title":["Prognostic Implication of Admission Mean and Pulse Pressure in Acute Decompensated Heart Failure With Different Phenotypes"],"prefix":"10.1093","volume":"36","author":[{"given":"Chen","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital of Sun Yat-sen University , Guangzhou, Guangdong , China"},{"name":"NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University , Guangzhou, Guangdong , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuwei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, 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