{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:55:15Z","timestamp":1776214515013,"version":"3.50.1"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,6,3]],"date-time":"2023-06-03T00:00:00Z","timestamp":1685750400000},"content-version":"vor","delay-in-days":49,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Serious cardiovascular health disparities persist across the United States, disproportionately affecting Black communities. Mounting evidence supports negative social determinants of health (SDoH) as contributing factors to a higher prevalence of hypertension along with lower control rates. Here, we describe a first-of-a-kind approach to reducing health disparities by focusing on preventing hypertension in Black adults with elevated blood pressure (BP) living in socially vulnerable communities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>Linkage, Empowerment, and Access to Prevent Hypertension (LEAP-HTN) is part of the RESTORE (Addressing Social Determinants to Prevent Hypertension) health equity research network. The trial will test if a novel intervention reduces systolic BP (primary outcome) and prevents the onset of hypertension over 1 year versus usual care in 500 Black adults with elevated BP (systolic BP 120\u2013129 mm Hg; diastolic BP &amp;lt;80 mm Hg) in Detroit, Michigan. LEAP-HTN leverages our groundbreaking platform using geospatial health and social vulnerability data to direct the deployment of mobile health units (MHUs) to communities of greatest need. All patients are referred to primary care providers. Trial participants in the active limb will receive additional collaborative care delivered remotely by community health workers using an innovative strategy termed pragmatic, personalized, adaptable approaches to lifestyle, and life circumstances (PAL2) which mitigates the impact of negative SDoH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LEAP-HTN aims to prevent hypertension by improving access and linkage to care while mitigating negative SDoH. This novel approach could represent a sustainable and scalable strategy to overcoming health disparities in socially vulnerable communities across the United States.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ajh\/hpad009","type":"journal-article","created":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T17:00:42Z","timestamp":1674752442000},"page":"264-272","source":"Crossref","is-referenced-by-count":3,"title":["Linkage, Empowerment, and Access to Prevent Hypertension: A Novel Program to Prevent Hypertension and Reduce Cardiovascular Health Disparities in Detroit, Michigan"],"prefix":"10.1093","volume":"36","author":[{"given":"Ijeoma","family":"Nnodim Opara","sequence":"first","affiliation":[{"name":"Departments of Internal Medicine and Pediatrics, Wayne State University , Detroit, MI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert D","family":"Brook","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases, Department of Internal Medicine, Wayne State University , Detroit, MI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J","family":"Twiner","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Wayne State University , Detroit, MI ,","place":["USA"]},{"name":"Integrative Biosciences Center, Wayne State University , Detroit, MI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katee","family":"Dawood","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Wayne State University , Detroit, MI ,","place":["USA"]},{"name":"Integrative Biosciences Center, Wayne State University , Detroit, MI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7306-5620","authenticated-orcid":false,"given":"Phillip D","family":"Levy","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Wayne State University , Detroit, MI ,","place":["USA"]},{"name":"Integrative Biosciences Center, Wayne State University , Detroit, MI ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,4,15]]},"reference":[{"key":"2026041420043484200_CIT0001","volume-title":"Deaths: Final data for 2018. 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