{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T02:25:07Z","timestamp":1772504707853,"version":"3.50.1"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T00:00:00Z","timestamp":1677196800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000035","name":"Institute of Nutrition, Metabolism and Diabetes","doi-asserted-by":"publisher","award":["PJT-175027"],"award-info":[{"award-number":["PJT-175027"]}],"id":[{"id":"10.13039\/501100000035","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000191","name":"Kidney Foundation of Canada","doi-asserted-by":"publisher","award":["851937-21KHRG"],"award-info":[{"award-number":["851937-21KHRG"]}],"id":[{"id":"10.13039\/501100000191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DK115392, R01 HL153004, and R01 DK16618"],"award-info":[{"award-number":["R01 DK115392, R01 HL153004, and R01 DK16618"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004411","name":"Heart and Stroke Foundation of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004411","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National New Investigator Award"},{"DOI":"10.13039\/501100020951","name":"Fonds de recherche du Qu\u00e9bec","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020951","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Sant\u00e9"},{"name":"Soci\u00e9t\u00e9 qu\u00e9b\u00e9coise d\u2019hypertension art\u00e9rielle"},{"name":"Bourse Jacques-de-Champlain"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>BACKGROUND<\/jats:title>\n                  <jats:p>Hypertension plus obstructive sleep apnea (OSA) is recommended in some guidelines as an indication to screen for primary aldosteronism (PA), yet prior data has brought the validity of this recommendation into question. Given this context, it remains unknown whether this screening recommendation is being implemented into clinical practice.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>We conducted a population-based retrospective cohort study of all adult Ontario (Canada) residents with hypertension plus OSA from 2009 to 2020 with follow-up through 2021 utilizing provincial health administrative data. We measured the proportion of individuals who underwent PA screening via the aldosterone-to-renin ratio by year. We further examined screening rates among patients with hypertension plus OSA by the presence of concurrent hypokalemia and resistant hypertension. Clinical predictors associated with screening were assessed via Cox regression modeling.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The study cohort included 53,130 adults with both hypertension and OSA, of which only 634 (1.2%) underwent PA screening. Among patients with hypertension, OSA, and hypokalemia, the proportion of eligible patients screened increased to 2.8%. Among patients \u226565 years with hypertension, OSA, and prescription of \u22654 antihypertensive medications, the proportion of eligible patients screened was 1.8%. Older age was associated with a decreased likelihood of screening while hypokalemia and subspecialty care with internal medicine, cardiology, endocrinology, or nephrology were associated with an increased likelihood of screening. No associations with screening were identified with sex, rural residence, cardiovascular disease, diabetes, or respirology subspecialty care.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The population-level uptake of the guideline recommendation to screen all patients with hypertension plus OSA for PA is exceedingly low.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajh\/hpad022","type":"journal-article","created":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T19:19:50Z","timestamp":1677266390000},"page":"363-371","source":"Crossref","is-referenced-by-count":9,"title":["Screening for Primary Aldosteronism Among Hypertensive Adults with Obstructive Sleep Apnea: A Retrospective Population-Based Study"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3559-3531","authenticated-orcid":false,"given":"Gregory L","family":"Hundemer","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine, University of Ottawa , Ottawa, Ontario , Canada"},{"name":"Ottawa Hospital Research Institute, University of Ottawa , Ottawa, Ontario , Canada"},{"name":"ICES (formerly Institute for Clinical Evaluative Sciences) , Ottawa , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haris","family":"Imsirovic","sequence":"additional","affiliation":[{"name":"ICES (formerly Institute for Clinical Evaluative Sciences) , Ottawa , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetyana","family":"Kendzerska","sequence":"additional","affiliation":[{"name":"Ottawa Hospital Research Institute, University of Ottawa , Ottawa, Ontario , Canada"},{"name":"ICES (formerly Institute for Clinical Evaluative Sciences) , Ottawa , Canada"},{"name":"Division of Respirology, Department of Medicine, University of Ottawa , Ottawa, Ontario , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand","family":"Vaidya","sequence":"additional","affiliation":[{"name":"Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women\u2019s Hospital, Harvard Medical School , Boston, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander A","family":"Leung","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Medicine, Cumming School of Medicine, University of Calgary , Calgary, Alberta , Canada"},{"name":"Department of Community Health Sciences, Cumming School of Medicine, University of Calgary , Calgary, Alberta , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory A","family":"Kline","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Medicine, Cumming School of Medicine, University of Calgary , Calgary, Alberta , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9mi","family":"Goupil","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, H\u00f4pital du Sacr\u00e9-Coeur de Montr\u00e9al, University of Montreal , Montreal, Quebec , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Madore","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, H\u00f4pital du Sacr\u00e9-Coeur de Montr\u00e9al, University of Montreal , Montreal, Quebec , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohsen","family":"Agharazii","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, CHU de Qu\u00e9bec-Universit\u00e9 Laval , Quebec City, Quebec , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg","family":"Knoll","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, University of Ottawa , Ottawa, Ontario , Canada"},{"name":"Ottawa Hospital Research Institute, University of Ottawa , Ottawa, Ontario , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish M","family":"Sood","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, University of Ottawa , Ottawa, Ontario , Canada"},{"name":"Ottawa Hospital Research Institute, University of Ottawa , Ottawa, Ontario , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,2,24]]},"reference":[{"key":"2023061507124485000_CIT0001","doi-asserted-by":"crossref","first-page":"10","DOI":"10.7326\/M20-0065","article-title":"The unrecognized prevalence of primary aldosteronism: a cross-sectional study","volume":"173","author":"Brown","year":"2020","journal-title":"Ann Intern Med"},{"key":"2023061507124485000_CIT0002","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1016\/j.jacc.2017.01.052","article-title":"Prevalence and clinical manifestations of primary aldosteronism encountered in primary care practice","volume":"69","author":"Monticone","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2023061507124485000_CIT0003","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1161\/01.HYP.0000079505.25750.11","article-title":"Primary aldosteronism and hypertensive disease","volume":"42","author":"Mosso","year":"2003","journal-title":"Hypertension"},{"key":"2023061507124485000_CIT0004","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1291\/hypres.27.193","article-title":"Prospective study on the prevalence of secondary hypertension among hypertensive patients visiting a general outpatient clinic in Japan","volume":"27","author":"Omura","year":"2004","journal-title":"Hypertens Res"},{"key":"2023061507124485000_CIT0005","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1016\/j.jacc.2006.07.059","article-title":"A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients","volume":"48","author":"Rossi","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"2023061507124485000_CIT0006","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S2213-8587(17)30319-4","article-title":"Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis","volume":"6","author":"Monticone","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2023061507124485000_CIT0007","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1001\/jamacardio.2018.2003","article-title":"Incidence of atrial fibrillation and mineralocorticoid receptor activity in patients with medically and surgically treated primary aldosteronism","volume":"3","author":"Hundemer","year":"2018","journal-title":"JAMA Cardiol"},{"key":"2023061507124485000_CIT0008","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S2213-8587(17)30367-4","article-title":"Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study","volume":"6","author":"Hundemer","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2023061507124485000_CIT0009","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline","volume":"101","author":"Funder","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"2023061507124485000_CIT0010","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/1470320310366581","article-title":"Renin-angiotensin-aldosterone system in patients with sleep apnoea: prevalence of primary aldosteronism","volume":"11","author":"Di Murro","year":"2010","journal-title":"J Renin Angiotensin Aldosterone Syst"},{"key":"2023061507124485000_CIT0011","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1161\/HYPERTENSIONAHA.120.16902","article-title":"Prospective screening for primary aldosteronism in patients with suspected obstructive sleep apnea","volume":"77","author":"Chee","year":"2021","journal-title":"Hypertension"},{"key":"2023061507124485000_CIT0012","doi-asserted-by":"crossref","first-page":"629","DOI":"10.5664\/jcsm.8960","article-title":"Primary aldosteronism is highly prevalent in patients with hypertension and moderate to severe obstructive sleep apnea","volume":"17","author":"Dobrowolski","year":"2021","journal-title":"J Clin Sleep Med"},{"key":"2023061507124485000_CIT0013","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1055\/s-0043-122887","article-title":"Primary aldosteronism and obstructive sleep apnea: is this a bidirectional relationship?","volume":"49","author":"Prejbisz","year":"2017","journal-title":"Horm Metab Res"},{"key":"2023061507124485000_CIT0014","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1378\/chest.125.1.112","article-title":"Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea","volume":"125","author":"Calhoun","year":"2004","journal-title":"Chest"},{"key":"2023061507124485000_CIT0015","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/jhh.2017.28","article-title":"Treatment of primary aldosteronism is associated with a reduction in the severity of obstructive sleep apnoea","volume":"31","author":"Wolley","year":"2017","journal-title":"J Hum Hypertens"},{"key":"2023061507124485000_CIT0016","doi-asserted-by":"crossref","first-page":"464","DOI":"10.3109\/10641963.2015.1131290","article-title":"Effect of spironolactone on patients with resistant hypertension and obstructive sleep apnea","volume":"38","author":"Yang","year":"2016","journal-title":"Clin Exp Hypertens"},{"key":"2023061507124485000_CIT0017","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/jhh.2009.96","article-title":"Spironolactone reduces severity of obstructive sleep apnoea in patients with resistant hypertension: a preliminary report","volume":"24","author":"Gaddam","year":"2010","journal-title":"J Hum Hypertens"},{"key":"2023061507124485000_CIT0018","doi-asserted-by":"crossref","first-page":"363","DOI":"10.5664\/jcsm.27878","article-title":"Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension","volume":"6","author":"Gonzaga","year":"2010","journal-title":"J Clin Sleep Med"},{"key":"2023061507124485000_CIT0019","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1378\/chest.12-0802","article-title":"Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronism","volume":"143","author":"Pimenta","year":"2013","journal-title":"Chest"},{"key":"2023061507124485000_CIT0020","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1378\/chest.06-1442","article-title":"Plasma aldosterone is related to severity of obstructive sleep apnea in subjects with resistant hypertension","volume":"131","author":"Pratt-Ubunama","year":"2007","journal-title":"Chest"},{"key":"2023061507124485000_CIT0021","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1055\/a-1133-7255","article-title":"Primary aldosteronism and obstructive sleep apnea: casual association or pathophysiological link?","volume":"52","author":"Pecori","year":"2020","journal-title":"Horm Metab Res"},{"key":"2023061507124485000_CIT0022","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1097\/00005344-200111002-00013","article-title":"The endothelin-aldosterone axis and cardiovascular diseases","volume":"38","author":"Rossi","year":"2001","journal-title":"J Cardiovasc Pharmacol"},{"key":"2023061507124485000_CIT0023","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1172\/JCI115367","article-title":"Hypoxia induces endothelin gene expression and secretion in cultured human endothelium","volume":"88","author":"Kourembanas","year":"1991","journal-title":"J Clin Invest"},{"key":"2023061507124485000_CIT0024","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1161\/HYPERTENSIONAHA.119.13833","article-title":"Primary aldosteronism and obstructive sleep apnea: a cross-sectional multi-ethnic study","volume":"74","author":"Buffolo","year":"2019","journal-title":"Hypertension"},{"key":"2023061507124485000_CIT0025","author":"Statistics Canada."},{"key":"2023061507124485000_CIT0026","doi-asserted-by":"crossref","first-page":"e1001885","DOI":"10.1371\/journal.pmed.1001885","article-title":"The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement","volume":"12","author":"Benchimol","year":"2015","journal-title":"PLoS Med"},{"key":"2023061507124485000_CIT0027","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.ypmed.2007.08.012","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"45","author":"von Elm","year":"2007","journal-title":"Prev Med"},{"key":"2023061507124485000_CIT0028","first-page":"67","article-title":"Coding accuracy of administrative drug claims in the Ontario drug benefit database","volume":"10","author":"Levy","year":"2003","journal-title":"Can J Clin Pharmacol"},{"key":"2023061507124485000_CIT0029","author":"Statistics Canada"},{"key":"2023061507124485000_CIT0030","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1161\/HYPERTENSIONAHA.109.139279","article-title":"Validation of a case definition to define hypertension using administrative data","volume":"54","author":"Quan","year":"2009","journal-title":"Hypertension"},{"key":"2023061507124485000_CIT0031","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1503\/cmaj.071283","article-title":"Prevalence and incidence of hypertension from 1995 to 2005: a population-based study","volume":"178","author":"Tu","year":"2008","journal-title":"CMAJ"},{"key":"2023061507124485000_CIT0032","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/ALN.0000000000000692","article-title":"Identifying obstructive sleep apnea in administrative data: a study of diagnostic accuracy","volume":"123","author":"McIsaac","year":"2015","journal-title":"Anesthesiology"},{"key":"2023061507124485000_CIT0033","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2147\/CLEP.S308852","article-title":"Case-ascertainment models to identify adults with obstructive sleep apnea using health administrative data: internal and external validation","volume":"13","author":"Kendzerska","year":"2021","journal-title":"Clin Epidemiol"},{"key":"2023061507124485000_CIT0034","doi-asserted-by":"crossref","first-page":"289","DOI":"10.7326\/M20-4873","article-title":"Testing for primary aldosteronism and mineralocorticoid receptor antagonist use among U.S. veterans: a retrospective cohort study","volume":"174","author":"Cohen","year":"2021","journal-title":"Ann Intern Med"},{"issue":"6","key":"2023061507124485000_CIT0035","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1001\/jamasurg.2021.0254","article-title":"Outcomes of a specialized clinic on rates of investigation and treatment of primary aldosteronism","volume":"156","author":"Liu","year":"2021","journal-title":"JAMA Surg"},{"key":"2023061507124485000_CIT0036","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1210\/er.2018-00139","article-title":"The expanding spectrum of primary aldosteronism: implications for diagnosis, pathogenesis, and treatment","volume":"39","author":"Vaidya","year":"2018","journal-title":"Endocr Rev"},{"key":"2023061507124485000_CIT0037","doi-asserted-by":"crossref","first-page":"4826","DOI":"10.1210\/jc.2013-2805","article-title":"Long-term cardio- and cerebrovascular events in patients with primary aldosteronism","volume":"98","author":"Mulatero","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2023061507124485000_CIT0038","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1161\/HYPERTENSIONAHA.121.18118","article-title":"Screening rates for primary aldosteronism among individuals with hypertension plus hypokalemia: a population-based retrospective cohort study","volume":"79","author":"Hundemer","year":"2021","journal-title":"Hypertension"},{"key":"2023061507124485000_CIT0039","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1093\/aje\/kws342","article-title":"Increased prevalence of sleep-disordered breathing in adults","volume":"177","author":"Peppard","year":"2013","journal-title":"Am J Epidemiol"},{"key":"2023061507124485000_CIT0040","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s11906-001-0040-8","article-title":"Are sleep-related breathing disorders important contributing factors to the production of essential hypertension?","volume":"3","author":"Silverberg","year":"2001","journal-title":"Curr Hypertens Rep"},{"key":"2023061507124485000_CIT0041","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1161\/HYPERTENSIONAHA.119.14359","article-title":"Screening rates for primary aldosteronism in resistant hypertension: a cohort study","volume":"75","author":"Jaffe","year":"2020","journal-title":"Hypertension"},{"key":"2023061507124485000_CIT0042","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.surg.2018.05.085","article-title":"Keeping primary aldosteronism in mind: deficiencies in screening at-risk hypertensives","volume":"165","author":"Ruhle","year":"2019","journal-title":"Surgery"},{"key":"2023061507124485000_CIT0043","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.surg.2019.05.087","article-title":"Adherence to consensus guidelines for screening of primary aldosteronism in an urban healthcare system","volume":"167","author":"Sivarajah","year":"2020","journal-title":"Surgery"},{"key":"2023061507124485000_CIT0044","first-page":"e13","article-title":"2017 ACC\/AHA\/AAPA\/ABC\/ACPM\/AGS\/APhA\/ASH\/ASPC\/NMA\/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"71","author":"Whelton","year":"2018","journal-title":"Hypertension"},{"key":"2023061507124485000_CIT0045","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.cjca.2016.02.066","article-title":"2016 Canadian Hypertension Education Program Guidelines for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension","volume":"32","author":"Leung","year":"2016","journal-title":"Can J Cardiol"}],"container-title":["American Journal of Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ajh\/advance-article-pdf\/doi\/10.1093\/ajh\/hpad022\/49504871\/hpad022.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajh\/article-pdf\/36\/7\/363\/50570760\/hpad022.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ajh\/article-pdf\/36\/7\/363\/50570760\/hpad022.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T07:13:51Z","timestamp":1686813231000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajh\/article\/36\/7\/363\/7057816"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,24]]},"references-count":45,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,2,24]]},"published-print":{"date-parts":[[2023,6,15]]}},"URL":"https:\/\/doi.org\/10.1093\/ajh\/hpad022","relation":{},"ISSN":["0895-7061","1941-7225"],"issn-type":[{"value":"0895-7061","type":"print"},{"value":"1941-7225","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,7,1]]},"published":{"date-parts":[[2023,2,24]]}}}