{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:02:45Z","timestamp":1792785765735,"version":"4.5.0"},"reference-count":75,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"UCLouvain, Belgium","award":["CDR 40003453"],"award-info":[{"award-number":["CDR 40003453"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fibromuscular dysplasia (FMD) is an idiopathic and systemic non-inflammatory and non-atherosclerotic arterial disease. Fifteen to 25% of patients with FMD present with arterial dissection in at least one arterial bed. Conversely, a substantial number of patients with renal, carotid, and visceral dissection have underlying FMD. Also, while few patients with FMD develop coronary artery dissection, lesions suggestive of multifocal FMD have been reported in 30\u201380% of patients with spontaneous coronary artery dissection (SCAD), and the relation between these two entities remains controversial. The frequent association of FMD with arterial dissection, both in coronary and extra-coronary arteries raises a number of practical and theoretical questions: (i) Are FMD and arterial dissections two different facets of the same disease or distinct though related entities? (ii) Is SCAD just a manifestation of coronary FMD or a different disease? (iii) What is the risk and which are predictive factors of developing arterial dissection in a patient with FMD? (iv) What proportion of patients who experienced an arterial dissection have underlying FMD, and does this finding influence the risk of subsequent arterial complications? In this review we will address these different questions using fragmentary, mostly cross-sectional evidence derived from large registries and studies from Europe and the United States, as well as arguments derived from demographics, clinical presentation, imaging, and when available histology and genetics. From there we will derive practical consequences for nosology, screening and follow-up.<\/jats:p>","DOI":"10.1093\/ajh\/hpad056","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T12:48:29Z","timestamp":1687870109000},"page":"573-585","source":"Crossref","is-referenced-by-count":26,"title":["From Fibromuscular Dysplasia to Arterial Dissection and Back"],"prefix":"10.1093","volume":"36","author":[{"given":"Justine","family":"Huart","sequence":"first","affiliation":[{"name":"Division of Nephrology, University of Li\u00e8ge Hospital (ULi\u00e8ge CHU), University of Li\u00e8ge , Li\u00e8ge , Belgium"},{"name":"Groupe Interdisciplinaire de G\u00e9noprot\u00e9omique Appliqu\u00e9e (GIGA), Division of Cardiovascular Sciences, University of Li\u00e8ge , Li\u00e8ge , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria S","family":"Stoenoiu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Rheumatology, Cliniques Universitaires Saint-Luc, Universit\u00e9 catholique de Louvain , Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marialuisa","family":"Zedde","sequence":"additional","affiliation":[{"name":"Neurology Unit, Stroke Unit, AUSL-IRCCS di Reggio Emilia , Reggio Emilia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Pascarella","sequence":"additional","affiliation":[{"name":"Neuroradiology Unit, AUSL-IRCCS di Reggio Emilia , Reggio Emilia , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Adlam","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre , Leicester , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4007-9695","authenticated-orcid":false,"given":"Alexandre","family":"Persu","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cliniques Universitaires Saint-Luc, Universit\u00e9 catholique de Louvain , Brussels , Belgium"},{"name":"Pole of Cardiovascular Research, Institut de Recherche Exp\u00e9rimentale et Clinique, Universit\u00e9 catholique de Louvain , Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"key":"2023101306283388500_CIT0001","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1177\/1358863X18821816","article-title":"First International Consensus on the diagnosis and management of fibromuscular dysplasia","volume":"24","author":"Gornik","year":"2019","journal-title":"Vasc 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