{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T10:56:20Z","timestamp":1782816980489,"version":"3.54.5"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T00:00:00Z","timestamp":1705017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008273","name":"Novartis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008273","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>BACKGROUND<\/jats:title>\n                  <jats:p>Hypertension is the leading risk factor for cardiovascular diseases (CVDs) and a major public health issue worldwide. In Brazil, it affects approximately 52.5% of the adult population. We describe the solutions package and the impact of a population health initiative in S\u00e3o Paulo city, following the CARDIO4Cities approach for the management of cardiovascular risk.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Using a design thinking approach, interventions were developed with a coalition of local and international stakeholders to address needs of patients, healthcare professionals, and the health system. The resulting solution package was checked to comply with guidelines for non-communicable disease and hypertension management. Clinical impact was measured by extracting the hypertension cascade of care\u2014monitored, diagnosis, treatment, and control\u2014from medical records.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Under the leadership of the municipal health authorities, nine solutions were piloted and scaled across the city. Solutions conform with local and international best-practices. Between October 2017 and December 2021, 11,406 patient records were analyzed. Results showed a 40% increase in monitored patients (patients with at least one blood pressure, BP, measurement); reduced proportions of patients diagnosed among those with available BP measurements (72%\u201353%) and treated among diagnosed (93%\u201385%); and an improvement in controlled patients among those receiving treatment (16%\u201327%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The solution package described in this study was correlated with increased BP control. The implementation methodology and results add to the body of real-world evidence supporting population health implementation science in Brazil and beyond.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajh\/hpae005","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T12:12:45Z","timestamp":1705061565000},"page":"366-378","source":"Crossref","is-referenced-by-count":6,"title":["An Intersectoral Approach to Hypertension Care: Solutions for Improving Blood Pressure Control in S\u00e3o Paulo, Brazil"],"prefix":"10.1093","volume":"37","author":[{"given":"\u00c1lvaro","family":"Avezum","sequence":"first","affiliation":[{"name":"Hospital Alem\u00e3o Oswaldo Cruz , S\u00e3o Paulo , Brazil"},{"name":"Sociedade de Cardiologia do Estado de S\u00e3o Paulo (SOCESP) , S\u00e3o Paulo , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano F","family":"Drager","sequence":"additional","affiliation":[{"name":"Sociedade de Cardiologia do Estado de S\u00e3o Paulo (SOCESP) , S\u00e3o Paulo , Brazil"},{"name":"Unidade de Hipertens\u00e3o, Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP Faculdade de Medicina Universidade de S\u00e3o Paulo , S\u00e3o Paulo , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Reiker","sequence":"additional","affiliation":[{"name":"Novartis Foundation , Basel , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Bigoni","sequence":"additional","affiliation":[{"name":"IQVIA , S\u00e3o Paulo , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lays P","family":"Leonel","sequence":"additional","affiliation":[{"name":"IQVIA , S\u00e3o Paulo , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane","family":"Abreu","sequence":"additional","affiliation":[{"name":"IQVIA , S\u00e3o Paulo , 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