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Multivariable linear regression analyses were performed to evaluate the associations of nighttime and daytime BP with cardiac biomarker levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The mean age was 69\u2005\u00b1\u200512 years, 28% were African American, and mean nighttime and daytime SBP were 121\u2005\u00b1\u200516 mm Hg and 132\u2005\u00b1\u200514 mm Hg, respectively. In multivariable models, compared with the lowest tertile of nighttime systolic BP, the highest tertile was associated with 48% higher NT-proBNP levels (adjusted geometric mean ratio [GMR]\u2005=\u20051.48, 95% CI: 1.22, 1.79), and 19% higher hs-cTnT levels (adjusted GMR\u2005=\u20051.19, 95% CI: 1.07, 1.32). In contrast, the highest vs. lowest tertile of daytime systolic BP was not associated with NT-proBNP (adjusted GMR\u2005=\u20051.09, 95% CI: 0.88, 1.34), but was associated with 16% higher hs-cTnT levels (adjusted GMR\u2005=\u20051.16, 95% CI: 1.04, 1.30). Similar results were observed using diastolic BP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>In SPRINT, both higher nighttime and daytime BP were independently associated with higher hs-cTnT levels, but only higher nighttime BP was associated with higher NT-proBNP levels.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ajh\/hpae035","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T12:17:55Z","timestamp":1711714675000},"page":"571-579","source":"Crossref","is-referenced-by-count":1,"title":["Associations of Ambulatory Blood Pressure Measurements With High-Sensitivity Troponin and Natriuretic Peptide Levels in SPRINT"],"prefix":"10.1093","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2289-3079","authenticated-orcid":false,"given":"Nikit","family":"Venishetty","sequence":"first","affiliation":[{"name":"Department of Medicine, Paul L. 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DeBakey Veterans Affairs Medical Center , Houston, Texas ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christie M","family":"Ballantyne","sequence":"additional","affiliation":[{"name":"Department of Medicine and Center for Cardiometabolic Disease Prevention, Baylor College of Medicine , Houston, Texas ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony A","family":"Killeen","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, University of Minnesota Medical School , Minneapolis, Minnesota ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim H","family":"Ix","sequence":"additional","affiliation":[{"name":"Nephrology Section, Veterans Affairs San Diego Healthcare System , San Diego, California ,","place":["USA"]},{"name":"Division of Nephrology-Hypertension, University of California San Diego , San Diego, California 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