{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T09:54:14Z","timestamp":1792403654150,"version":"4.4.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:00:00Z","timestamp":1712275200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>The prevalence of many chronic conditions has increased among US adults. Many adults with hypertension have other chronic conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We estimated changes in the age-adjusted prevalence of multiple (\u22653) chronic conditions, not including hypertension, using data from the National Health and Nutrition Examination Survey, from 1999\u20132000 to 2017\u20132020, among US adults with (n = 24,851) and without (n = 24,337 hypertension. Hypertension included systolic blood pressure (BP) \u2265130 mm Hg, diastolic BP \u226580 mm Hg, or antihypertensive medication use. We studied 14 chronic conditions: arthritis, asthma, cancer, coronary heart disease, chronic kidney disease, depression, diabetes, dyslipidemia, hepatitis B, hepatitis C, heart failure, lung disease, obesity, and stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>From 1999\u20132000 to 2017\u20132020, the age-adjusted mean number of chronic conditions increased more among US adults with vs. without hypertension (2.2 to 2.8 vs. 1.7 to 2.0; P-interaction &amp;lt;0.001). Also, the age-adjusted prevalence of multiple chronic conditions increased from 39.0% to 52.0% among US adults with hypertension and from 26.0% to 30.0% among US adults without hypertension (P-interaction\u2005=\u20050.022). In 2017\u20132020, after age, gender, and race\/ethnicity adjustment, US adults with hypertension were 1.94 (95% confidence interval: 1.72\u20132.18) times as likely to have multiple chronic conditions compared to those without hypertension. In 2017\u20132020, dyslipidemia, obesity, and arthritis were the most common 3 co-occurring chronic conditions among US adults with and without hypertension (age-adjusted prevalence 16.5% and 3.1%, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>In 2017\u20132020, more than half of US adults with hypertension had \u22653 additional chronic conditions, a substantial increase from 20 years ago.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ajh\/hpae040","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T05:51:35Z","timestamp":1712296295000},"page":"493-502","source":"Crossref","is-referenced-by-count":20,"title":["Trends in the Prevalence of Multiple Chronic Conditions Among US Adults With Hypertension From 1999\u20132000 Through 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