{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T06:26:49Z","timestamp":1740119209168,"version":"3.37.3"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>BACKGROUND<\/jats:title>\n                  <jats:p>This study aimed to elucidate the prognostic role of Masked Morning Hypertension (MMH) in non-dialysis-dependent chronic kidney disease (NDD-CKD).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>2,130 NDD-CKD patients of the inpatient department were categorized into four blood pressure (BP) groups: clinical normotension (CH\u2212), clinical hypertension (CH+) with morning hypertension (MH+), and without MH+ (MH\u2212) respectively. The correlation between these four BP types and the primary (all-cause mortality) and secondary endpoints (cardio-cerebrovascular disease [CVD] and end-stage kidney disease [ESKD]) was analyzed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The prevalence of MH and MMH were 47.4% and 14.98%, respectively. Morning hypertension independently increased the risk of all-cause mortality (P\u2005=\u20050.004) and CVD (P\u2005&amp;lt;\u20050.001) but not ESKD (P\u2005=\u20050.092). Masked morning hypertension was associated with heightened all-cause mortality (HR\u2005=\u20054.22, 95% CI\u2005=\u20051.31\u201313.59; P\u2005=\u20050.02) and CVD events (HR\u2005=\u20055.14, 95% CI\u2005=\u20051.37\u201319.23; P\u2005=\u20050.02), with no significant association with ESKD (HR\u2005=\u20051.18, 95% CI\u2005=\u20050.65\u20132.15; P\u2005=\u20050.60). When considering non-CVD deaths as a competing risk factor, a high cumulative incidence of CVD events was observed in the MMH group (HR\u2005=\u20055.16, 95% CI\u2005=\u20051.39\u201319.08).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>MMH is an independent risk factor for all-cause mortality and combined cardiovascular and cerebrovascular events in NDD-CKD patients, underscoring its prognostic significance. This highlights the need for comprehensive management of MH in this population.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajh\/hpae044","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T22:18:57Z","timestamp":1713305937000},"page":"621-630","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Effect of Masked Morning Hypertension in Chinese Inpatients With Non-dialysis Chronic Kidney Disease: A Multicenter Retrospective Study"],"prefix":"10.1093","volume":"37","author":[{"given":"Lin","family":"Lin","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University , 52 Meihua East Road, Zhuhai 519000, Guangdong , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinying","family":"Jiang","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University , 52 Meihua East Road, Zhuhai 519000, Guangdong , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingling","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University , 52 Meihua East Road, Zhuhai 519000, Guangdong , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingcan","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University , 52 Meihua East Road, Zhuhai 519000, Guangdong , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiantian","family":"Yu","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University , 52 Meihua East Road, Zhuhai 519000, Guangdong , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuting","family":"Wei","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University , 52 Meihua East Road, Zhuhai 519000, Guangdong , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Man","family":"Li","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University , Zhuhai 519000 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Peng","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Third Affiliated Hospital of Sun Yat-Sen University , Guangzhou , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1590-7954","authenticated-orcid":false,"given":"Cheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University , 52 Meihua East Road, Zhuhai 519000, Guangdong , China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"2024071505512238200_CIT0001","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1291\/hypres.29.679","article-title":"Regular alcohol drinking is a determinant of masked morning hypertension detected by home blood pressure monitoring in medicated hypertensive patients with well-controlled clinic blood pressure: the Jichi Morning Hypertension Research (J-MORE) study","volume":"29","author":"Ishikawa","year":"2006","journal-title":"Hypertens 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