{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T12:38:40Z","timestamp":1784637520368,"version":"3.55.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>BACKGROUND<\/jats:title>\n                  <jats:p>Blood pressure (BP) control can be difficult to attain due to multiple factors, including choosing and titrating antihypertensive medications. Measurement of hemodynamic parameters using impedance cardiography (ICG) at the point of care may allow better alignment of medication with the mechanism(s) underlying an individual\u2019s hypertension. We conducted a systematic review of randomized controlled trials of ICG compared to usual care for attainment of BP control.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>We searched Medline inclusive of the year 1946 to January 31, 2024, using a combination of MeSH terms and keywords. English-language articles were eligible for inclusion if they described results of a randomized controlled trial designed to compare ICG-guided BP-medication selection to usual care (i.e., clinician judgment\/guidelines-based alone) among a sample of hypertensive patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Of 1,952 titles screened, 6 trials met inclusion criteria. The first was published in 2002 from a specialty clinic in the United States, and the most recent in 2021 from a specialty clinic in China. One trial was conducted in a primary care setting. Sample sizes ranged from 102 to 164. Participants randomized to ICG-guided antihypertensive medication had reduced BP in the short-term to a greater extent than those randomized to usual care, with odds ratios for BP control (&amp;lt;140\/90 mm Hg) at 3 months ranging from 1.87 to 2.92. This effect was seen in both specialty clinics and in a primary care setting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Incorporation of ICG in the clinical setting may facilitate medication selection that leads to a greater proportion of patients obtaining BP control in the short term.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajh\/hpae090","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T19:20:21Z","timestamp":1720725621000},"page":"916-923","source":"Crossref","is-referenced-by-count":6,"title":["Use of Impedance Cardiography to Guide Blood Pressure Lowering Medication Selection: Systematic Review of Randomized Controlled Trials"],"prefix":"10.1093","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5770-2052","authenticated-orcid":false,"given":"Anthony J","family":"Viera","sequence":"first","affiliation":[{"name":"Department of Family Medicine and Community Health, Duke University School of Medicine , Durham, NC ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Hart","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health, Duke University School of Medicine , Durham, NC ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9472-6739","authenticated-orcid":false,"given":"Pedro","family":"Gomez Altamirano","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health, Duke University School of Medicine , Durham, NC ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandi","family":"Tuttle","sequence":"additional","affiliation":[{"name":"Medical Center Library & Archives, Duke University , Durham, NC ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Price","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health, Duke University School of Medicine , Durham, NC ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Sherwood","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine Department of Psychiatry and Behavioral Sciences, , Durham, NC ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,10,8]]},"reference":[{"key":"2024101405513914200_CIT0001","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.amepre.2010.02.016","article-title":"Deaths preventable in the U.S. by improvements in use of clinical preventive services","volume":"38","author":"Farley","year":"2010","journal-title":"Am J Prev Med"},{"key":"2024101405513914200_CIT0002","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1161\/HYPERTENSIONAHA.122.19222","article-title":"Blood pressure control among US adults, 2009 to 2012 through 2017 to 2020","volume":"79","author":"Muntner","year":"2022","journal-title":"Hypertension"},{"key":"2024101405513914200_CIT0003","doi-asserted-by":"crossref","first-page":"e127","DOI":"10.1016\/j.jacc.2017.11.006","article-title":"2017 ACC\/AHA\/AAPA\/ABC\/ACPM\/AGS\/APhA\/ASH\/ASPC\/NMA\/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"71","author":"Whelton","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2024101405513914200_CIT0004","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1001\/jama.289.19.2560","article-title":"The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report","volume":"289","author":"Chobanian","year":"2003","journal-title":"JAMA"},{"key":"2024101405513914200_CIT0005","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3399\/bjgp20X708053","article-title":"Diagnosis and management of hypertension in adults: NICE guideline update 2019","volume":"70","author":"Jones","year":"2020","journal-title":"Br J Gen Pract"},{"key":"2024101405513914200_CIT0006","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1136\/bmj.322.7292.977","article-title":"Evidence based management of hypertension. 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