{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T17:22:43Z","timestamp":1781112163648,"version":"3.54.1"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Omron Healthcare Co. Ltd"},{"DOI":"10.13039\/100007059","name":"Northwestern University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007059","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Automated patient messages based on home blood pressure (BP) may help overcome clinician and patient inertia in hypertension treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We designed and piloted an automated messaging system based on remote patient monitoring (RPM) results delivered through patients\u2019 electronic health record portal. Messages included reminders to monitor, what to do if BP is above or below goal, and positive feedback when goal BP is achieved; these were triggered via a deterministic algorithm based on reported home BPs. Seven clinicians agreed to participate in this pilot study. Patients with the most recent two office BPs \u2265140\/90 mmHg were eligible. Outcomes assessed after 9 months included change in home SBP, net change in antihypertensive medication, and number of automated messages. Subgroup analysis was conducted by baseline home BP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of 285 eligible patients, 70 (25%) enrolled. Baseline mean (SD) office systolic\/diastolic BP was 148(18)\/81(12) mmHg. By 9 months, participants had received a mean (range) of 13 (5\u201344) messages and viewed 85%. Among 64 patients completing the 9-month study visit, the baseline home BP was 142(17)\/84(15) mmHg, 9-month change in home SBP was \u22129.4 mmHg (95% CI: \u22121.3, \u221214.7). Among 13 patients with controlled baseline home BP (&amp;lt;130\/80 mmHg), SBP change was +2.7 mmHg (\u22124.8, +12.3). Among 51 patients with uncontrolled baseline home BP, SBP change was \u221212.5 mmHg (\u22125.2, \u221216.8); 51% had antihypertensive pharmacotherapy increased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Delivering automated feedback based on RPM BP results through a commercial electronic health record was feasible. Participants with sustained hypertension had large BP declines.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ajh\/hpaf142","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T12:14:57Z","timestamp":1759234497000},"page":"251-255","source":"Crossref","is-referenced-by-count":2,"title":["Development and Pilot Testing of Hypertension Management Support With EHR-Integrated Telemonitoring and Proactive Patient Messaging"],"prefix":"10.1093","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2462-1314","authenticated-orcid":false,"given":"Stephen D","family":"Persell","sequence":"first","affiliation":[{"name":"Division of General Internal Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University , Chicago, Illinois ,","place":["USA"]},{"name":"Center for Primary Care Innovation, Institute for Public Health and Medicine, Feinberg School of Medicine, Northwestern University , Chicago, Illinois 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C","family":"Petito","sequence":"additional","affiliation":[{"name":"Division of Biostatistics and Informatics, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University , Chicago, Illinois ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironori","family":"Sato","sequence":"additional","affiliation":[{"name":"Data Analytics Department, Technology Development HQ, Omron Healthcare, Co., Ltd. , Kyoto ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"2026020915215643600_CIT0001","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1161\/HYPERTENSIONAHA.121.17660","article-title":"Estimation of the global gap in clinic visits for hypertension care between patient need and physician 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