{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T09:33:57Z","timestamp":1786700037918,"version":"build-2736575974"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32260214"],"award-info":[{"award-number":["32260214"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Institutional Research Grant of the Second Affiliated Hospital of Nanchang University","award":["2023efyA03"],"award-info":[{"award-number":["2023efyA03"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Selective adrenal arterial embolization (SAAE) is an alternative treatment for unilateral primary aldosteronism (PA), but its overall success remains variable. We evaluated whether coil-assisted ethanol embolization (Coil-E) improves outcomes compared with ethanol embolization alone in patients undergoing single-vessel SAAE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective study, patients with unilateral PA who underwent single-vessel SAAE between 2020 and 2021 were categorized into Coil-E and ethanol groups. The primary endpoint was clinical success at 12 months defined according to the Primary Aldosteronism Surgical Outcome (PASO) criteria. Secondary endpoints included biochemical success, changes in 24-hour ambulatory blood pressure (BP), and safety outcomes. Propensity score-based analyses were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty-two patients were included (23 Coil-E, 59 ethanol). At 12 months, complete clinical success occurred in 17.4% vs 20.3%, partial success in 47.8% vs 35.6%, and absent success in 34.8% vs 44.1% (Coil-E vs ethanol; all P\u2009&amp;gt; 0.05). Complete biochemical success occurred in 39.1% vs 55.9%, whereas absent biochemical success occurred in 34.8% vs 28.8%. Mean 24-hour systolic\/diastolic BP decreased by 21.6\/10.1 mmHg in the Coil-E group and 20.5\/9.7 mmHg in the ethanol group, with no significant between-group differences. Serum potassium and aldosterone improved in both groups without deterioration in renal function or cortisol levels. No major procedure-related complications occurred. Findings were consistent across adjusted analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among patients with unilateral PA undergoing single-vessel SAAE, Coil-E was not associated with improved PASO-defined clinical or biochemical success compared with ethanol embolization alone.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ajh\/hpag061","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T11:47:39Z","timestamp":1781783259000},"page":"1067-1075","source":"Crossref","is-referenced-by-count":0,"title":["No incremental benefit of coil-assisted over ethanol embolization in unilateral primary aldosteronism"],"prefix":"10.1093","volume":"39","author":[{"given":"Zhi-Qiang","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University , Nanchang, Jiangxi,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning-Peng","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University , Nanchang, Jiangxi,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Liang","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University , Nanchang, Jiangxi,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University , Nanchang, Jiangxi,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Xin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University , Nanchang, Jiangxi,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6290-1491","authenticated-orcid":false,"given":"Yi-Fei","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University , Nanchang, Jiangxi,","place":["China"]},{"name":"Molecular Medicine of Jiangxi Key Laboratory, The Second Affiliated Hospital of Nanchang University , Nanchang, 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