{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T07:47:53Z","timestamp":1777621673419,"version":"3.51.4"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T00:00:00Z","timestamp":1493683200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>BACKGROUND<\/jats:title>\n                  <jats:p>Fibromuscular dysplasia (FMD) is a systemic, nonatherosclerotic, noninflammatory vasculopathy that is often overlooked by clinicians. Clinical clues could help in selecting patients for further evaluation for the presence of FMD. Recently, it was observed that tortuosity of the coronary arteries is often present in patients with FMD-related abnormalities of the coronary artery. Therefore, we wondered if the presence of coronary tortuosity might provide a clinical clue to the diagnosis of extracoronary FMD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CASES<\/jats:title>\n                  <jats:p>We describe 5 cases of FMD in whom diagnostic studies for FMD were initiated because of the presence of coronary tortuosity. FMD was found in all 5 patients in the renal and\/or cervical arteries.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Our 5 cases suggest that exertional chest pain in the presence of coronary tortuosity may be helpful in selecting patients for further evaluation for the presence of FMD. Further research should focus on the prevalence of FMD among patients with coronary tortuosity and whether the presence of additional clinical clues (such as the presence of hypertension at young age or pulsatile tinnitus) next to coronary tortuosity can predict the risk for FMD in individual patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajh\/hpx069","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T07:54:32Z","timestamp":1490946872000},"page":"776-780","source":"Crossref","is-referenced-by-count":14,"title":["Coronary Tortuosity: A Clue to the Diagnosis of Fibromuscular Dysplasia?"],"prefix":"10.1093","volume":"30","author":[{"given":"Daan J. L.","family":"van Twist","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre (MUMC+) 1 , Maastricht , The Netherlands ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter W.","family":"de Leeuw","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre (MUMC+) 1 , Maastricht , The Netherlands ;"},{"name":"Department of Internal Medicine, Zuyderland Medical Centre 2 , Sittard , The Netherlands ."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham A.","family":"Kroon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre (MUMC+) 1 , Maastricht , The Netherlands ;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,5,2]]},"reference":[{"key":"2022111818321820800_CIT0001","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1097\/HJH.0000000000000213","article-title":"European consensus on the diagnosis and management of fibromuscular dysplasia","volume":"32","author":"Persu","year":"2014","journal-title":"J Hypertens"},{"key":"2022111818321820800_CIT0002","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jacc.2016.04.044","article-title":"Dissection and aneurysm in patients with fibromuscular dysplasia: findings from the U.S. Registry for FMD","volume":"68","author":"Kadian-Dodov","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"2022111818321820800_CIT0003","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/j.jvir.2013.06.006","article-title":"Renal artery fibromuscular dysplasia in 2,640 renal donor subjects: a CT angiography analysis","volume":"24","author":"McKenzie","year":"2013","journal-title":"J Vasc Interv Radiol"},{"key":"2022111818321820800_CIT0004","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1097\/00007890-200204150-00018","article-title":"Incidence of donor renal fibromuscular dysplasia: does it justify routine angiography?","volume":"73","author":"Andreoni","year":"2002","journal-title":"Transplantation"},{"key":"2022111818321820800_CIT0005","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1148\/radiology.172.1.2662248","article-title":"Incidental fibromuscular dysplasia in potential renal donors: long-term clinical follow-up","volume":"172","author":"Cragg","year":"1989","journal-title":"Radiology"},{"key":"2022111818321820800_CIT0006","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1177\/1358863X14544715","article-title":"Is fibromuscular dysplasia underdiagnosed? 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