{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T06:26:50Z","timestamp":1740119210856,"version":"3.37.3"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2017,6,15]],"date-time":"2017-06-15T00:00:00Z","timestamp":1497484800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["1R25HL126145","1K01HL88735"],"award-info":[{"award-number":["1R25HL126145","1K01HL88735"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>BACKGROUND<\/jats:title>\n                  <jats:p>This study examined the degree to which sex, weight status, and the presence of hypertension and obesity in parents\/grandparents were associated with systolic (SBP) and diastolic (DBP) blood pressure (BP) among African American youth in a pilot offspring study examining obesity-related cardiovascular disease (CVD) risks among adolescents.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Data for this study were drawn from 212 adolescents (mean age 15.2 \u00b1 2.2 years, 50.5% female) participating in the Jackson Heart Kids Pilot Study \u2013 an offspring cohort study examining cardiovascular disease risks among descendants of Jackson Heart Study participants. SBP (mean 114.4 \u00b1 11.8 mm Hg) and DBP (mean 66.8 \u00b1 9.0 mm Hg) were the primary outcomes. Weight status (46.1% normal weight, 30.1% overweight, 23.6% obese) was the key independent variable. Other covariates were attempts to lose weight, fruit and vegetable consumption, physical activity, and spirituality.<\/jats:p>\n                  <jats:sec>\n                     <jats:title>RESULTS<\/jats:title>\n                     <jats:p>Fully adjusted linear regression models of the total sample produced results indicating that obesity was associated with BP (SBP: \u03b2 = 7.08, P &amp;lt; 0.01; DBP: \u03b2 = 8.14, P &amp;lt; 0.001). Sex-stratified analyses indicated that overweight and obesity were associated with SBP (overweight: \u03b2 = 6.77, P &amp;lt; 0.01; obese: \u03b2 = 11.65, P &amp;lt; 0.001) and obesity was correlated with DBP (\u03b2 = 9.86, P &amp;lt; 0.001) among males. For females, overweight was correlated with SBP (\u03b2 = 4.11, P &amp;lt; 0.05) while obesity was associated with DBP (\u03b2 = 6.98, P &amp;lt; 0.01). Attempting to lose weight was inversely related to SBP (\u03b2 = \u22124.01, P &amp;lt; 0.05) in the full sample and among males (\u03b2 = \u221211.94, P &amp;lt; 0.001). Familial presence of hypertension and\/or obesity was significantly associated with SBP among adolescent females but not males.<\/jats:p>\n                  <\/jats:sec>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The relationship between weight status, familial hypertension and obesity status, and BP among adolescents vary by sex. This study underscores the need for additional research investigating the relationship between individual sex, weight status, BP and familial BP, and obesity status on risk among African American adolescents.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajh\/hpx071","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T11:11:08Z","timestamp":1491390668000},"page":"892-898","source":"Crossref","is-referenced-by-count":5,"title":["Sex, Obesity, and Blood Pressure Among African American Adolescents: The Jackson Heart KIDS Pilot Study"],"prefix":"10.1093","volume":"30","author":[{"given":"Marino A","family":"Bruce","sequence":"first","affiliation":[{"name":"Center for Research on Men\u2019s Health, Vanderbilt University 1 , Nashville, Tennessee , USA ;"},{"name":"Center for Medicine, Health and Society, Vanderbilt University 2 , Nashville, Tennessee , USA ;"},{"name":"Myrlie Evers-Williams Institute for the Elimination of Health Disparities 3 , Jackson Mississippi , USA ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bettina M","family":"Beech","sequence":"additional","affiliation":[{"name":"Myrlie Evers-Williams Institute for the Elimination of Health Disparities 3 , Jackson Mississippi , USA ;"},{"name":"Department of Population Health Science, John D. Bower School of Population Health, University of Mississippi Medical Center 4 , Jackson, Mississippi , USA ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith C","family":"Norris","sequence":"additional","affiliation":[{"name":"David C. Geffen School of Medicine at UCLA 5 , Los Angeles, California , USA ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek M","family":"Griffith","sequence":"additional","affiliation":[{"name":"Center for Research on Men\u2019s Health, Vanderbilt University 1 , Nashville, Tennessee , USA ;"},{"name":"Center for Medicine, Health and Society, Vanderbilt University 2 , Nashville, Tennessee , USA ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Sims","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Mississippi Medical Center 6 , Jackson, Mississippi , USA ;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Roland J","family":"Thorpe","sequence":"additional","affiliation":[{"name":"Program for Research on Men\u2019s Health, Hopkins Center for Health Disparities Solutions 7 , Baltimore, Maryland , USA ;"},{"name":"Department of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health 8 , Baltimore, Maryland , USA ."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,6,15]]},"reference":[{"key":"2022111818051177800_CIT0001","doi-asserted-by":"crossref","first-page":"S213","DOI":"10.1542\/peds.2009-2107C","article-title":"Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report","volume":"128","author":"Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents; 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