{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T17:42:43Z","timestamp":1771609363377,"version":"3.50.1"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Hospital at home is an alternative means of providing inpatient care for a patient requiring prolonged liposomal amphotericin B therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Summary<\/jats:title><jats:p>Hospital at home is a unique care model that allows patients to receive inpatient hospital care within the comfort of their home and can be seen as an alternative care site for patients with complex treatment regimens that may require prolonged hospitalization. Hospital systems have increasingly begun incorporating hospital at home programs into their inpatient service lines. We present the case of a patient with disseminated histoplasmosis requiring a prolonged course of intravenous liposomal amphotericin B therapy. Because of the complex administration and stability of this medication, care is often provided in an inpatient setting. The Vanderbilt University Medical Center Hospital at Home team was able to coordinate resources and services to allow for this patient to receive acute hospital care at home and continue to receive amphotericin B infusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This experience spotlights how hospital at home can be considered for patients requiring ongoing inpatient care for prolonged intravenous treatment courses.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ajhp\/zxac331","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T17:58:38Z","timestamp":1667411918000},"page":"227-235","source":"Crossref","is-referenced-by-count":2,"title":["A hospital at home case report: Prolonged amphotericin B therapy via elastomeric pump"],"prefix":"10.1093","volume":"80","author":[{"given":"Tara","family":"Horr","sequence":"first","affiliation":[{"name":"Division of Geriatrics, Vanderbilt University Medical Center, Vanderbilt Hospital at Home , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Muscarella","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Services, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina","family":"Crocker","sequence":"additional","affiliation":[{"name":"Department of Hospital Medicine, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Kimmerling","sequence":"additional","affiliation":[{"name":"Hospital at Home, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy","family":"Reeves","sequence":"additional","affiliation":[{"name":"Hospital at Home, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion L","family":"Moreno","sequence":"additional","affiliation":[{"name":"Hospital at Home, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Hospital Medicine, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brett T","family":"Young","sequence":"additional","affiliation":[{"name":"Hospital at Home, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Ryan Starnes","sequence":"additional","affiliation":[{"name":"Hospital at Home, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina M","family":"Niehoff","sequence":"additional","affiliation":[{"name":"Vanderbilt Home Care Services , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil","family":"Kripalani","sequence":"additional","affiliation":[{"name":"Center for Health Services Research, Vanderbilt University Medical Center , Nashville, TN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,11,2]]},"reference":[{"issue":"9","key":"2023021517192768000_","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1086\/503043","article-title":"Antifungal therapy: lessons learned over the past 27 years","volume":"42","author":"Dismukes","year":"2006","journal-title":"Clin Infect Dis"},{"issue":"9","key":"2023021517192768000_","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s40265-013-0069-4","article-title":"Amphotericin B formulations: a comparative review of efficacy and toxicity","volume":"73","author":"Hamill","year":"2013","journal-title":"Drugs"},{"issue":"2","key":"2023021517192768000_","doi-asserted-by":"crossref","first-page":"105","DOI":"10.7326\/0003-4819-137-2-200207160-00008","article-title":"Safety and efficacy of liposomal amphotericin B compared with conventional amphotericin B for induction therapy of histoplasmosis in patients with AIDS","volume":"137","author":"Johnson","year":"2002","journal-title":"Ann Intern Med"},{"issue":"12","key":"2023021517192768000_","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1093\/cid\/cis290","article-title":"Does lipid emulsion reduce amphotericin B nephrotoxicity? 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