{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:57:34Z","timestamp":1791219454229,"version":"4.1.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Purpose<\/jats:title>\n                  <jats:p>While benzodiazepine prescribing among veterans with posttraumatic stress disorder (PTSD) declined substantially in the Veterans Health Administration over the past decade, little is known about current incident prescribing. Our objective was therefore to describe patient, provider, facility, and prescribing characteristics among veterans with PTSD who were incident benzodiazepine recipients in 2022 and contrast these to the characteristics for incident recipients in 2012.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This retrospective observational study included all veterans with PTSD who received an incident benzodiazepine prescription during calendar year 2022 and separately for 2012. The distribution of patient, provider, facility, and benzodiazepine prescribing characteristics was contrasted between years. Stratified subanalyses were conducted by potential non-PTSD benzodiazepine indication, including anxiety and sleep disorders.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 28,310 (6.6%) incident benzodiazepine recipients were identified in 2012, which decreased to 16,776 (1.9%) incident recipients in 2022. The proportion of initial prescriptions written for a days\u2019 supply of 30 or more days decreased from 75.6% to 51.7%, and the proportion who received a second prescription within 6 months decreased from 68.7% to 53.5%. The proportion of patients with diagnoses for potential benzodiazepine indications also increased, including for generalized anxiety disorder (15.1% increase), obsessive compulsive disorders (0.6% increase), panic disorder (6.7% increase), and sleep disorders (22.9% increase).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>As incident benzodiazepine prescribing among veterans with PTSD decreased over the past decade, so did the volume of drug dispensed and duration of therapy, while the prevalence of documented prescriptions for non-PTSD indications increased.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajhp\/zxae311","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T20:31:54Z","timestamp":1730233914000},"page":"e166-e172","source":"Crossref","is-referenced-by-count":1,"title":["Characteristics of incident benzodiazepine recipients among US veterans with posttraumatic stress disorder"],"prefix":"10.1093","volume":"82","author":[{"given":"Komel N","family":"Shahid","sequence":"first","affiliation":[{"name":"Iowa City Veterans Affairs Health Care System , Iowa City, IA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0513-4609","authenticated-orcid":false,"given":"Katherine","family":"Hadlandsmyth","sequence":"additional","affiliation":[{"name":"VA Office of Rural Health, Veterans Rural Health Resource Center\u2013Iowa City (VRHRC-IC), Iowa City Veterans Affairs Health Care System , Iowa City, IA"},{"name":"Department of Anesthesia, Carver College of Medicine, University of Iowa , Iowa City, IA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delaney R","family":"Brainerd","sequence":"additional","affiliation":[{"name":"Iowa City Veterans Affairs Health Care System , Iowa City, IA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian C","family":"Lund","sequence":"additional","affiliation":[{"name":"VA Office of Rural Health, Veterans Rural Health Resource Center\u2013Iowa City (VRHRC-IC), Iowa City Veterans Affairs Health Care System , Iowa City, IA"},{"name":"Center for Access & Delivery Research and Evaluation, Iowa City Veterans Affairs Health Care System , Iowa City, IA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,10,29]]},"reference":[{"key":"2025012418224973700_CIT0001","author":"Department of Veterans Affairs"},{"key":"2025012418224973700_CIT0002","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425787","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2022","edition":"5"},{"key":"2025012418224973700_CIT0003","volume-title":"Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder (PTSD) in Adults","author":"American Psychological Association","year":"2017"},{"key":"2025012418224973700_CIT0004","author":"Department of Veterans Affairs and Department of Defense"},{"issue":"4","key":"2025012418224973700_CIT0005","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1097\/PRA.0000000000000091","article-title":"Benzodiazepines for PTSD: a systematic review and meta-analysis","volume":"21","author":"Guina","year":"2015","journal-title":"J Psychiatr Pract"},{"issue":"3","key":"2025012418224973700_CIT0006","doi-asserted-by":"publisher","first-page":"21m14128","DOI":"10.4088\/JCP.21m14128","article-title":"Deimplementation of benzodiazepine prescribing in posttraumatic stress disorder in the Veterans Health Administration","volume":"83","author":"Bernardy","year":"2022","journal-title":"J Clin 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2004-2019","volume":"180","author":"Bykov","year":"2020","journal-title":"JAMA Intern Med"},{"issue":"12","key":"2025012418224973700_CIT0014","doi-asserted-by":"publisher","first-page":"3689","DOI":"10.1007\/s11606-021-06780-y","article-title":"Benzodiazepine prescribing from VA and Medicare to dually enrolled older veterans: a retrospective cohort study","volume":"36","author":"Lei","year":"2021","journal-title":"J Gen Intern Med"}],"container-title":["American Journal of Health-System 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