{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T07:02:55Z","timestamp":1793084575653,"version":"4.5.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"Supplement_5","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Purpose<\/jats:title>\n                  <jats:p>A customized Epic scoring tool for monitoring medications requiring renal dose adjustment utilizing Epic Bugsy and a custom renal function trend scoring column was developed and implemented in June 2023 at UT Southwestern Medical Center (UTSW) to replace the manual review and intervention (i-Vent) documentation process.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This retrospective, observational cohort study evaluated pharmacist interventions and antimicrobial dosing before and after implementation of the UTSW renal clinical pharmacist responsibility (CPR) dose adjustment tool. Adult patients (aged 18 years or older) requiring renal dose adjustment were included. The preintervention group included patients admitted between July 1 and August 31, 2022, whereas the postintervention group included patients admitted from July 1 through August 31, 2023. Patients exempt from the institutional automatic adult renal dosing guideline (ie, those with cystic fibrosis, solid organ transplantation, or bone marrow transplantation) or actively receiving renal replacement therapy during the index encounter were excluded.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In a comparable 2-month timespan, implementation of the renal CPR dose adjustment tool resulted in a 68.2% increase in the number of renal dosing interventions completed (P &amp;lt; 0.0001), a 47.2% reduction in the number of unique alerts requiring pharmacist review (P &amp;lt; 0.0001), and an increase in the proportion of actionable interventions per alert requiring review from 11.1% before implementation to 39.4% after implementation (P &amp;lt; 0.0001). Pharmacist satisfaction with the renal monitoring workflow also improved with implementation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In a comparable\u00a02-month\u00a0timespan, implementation of the\u00a0renal CPR dose adjustment tool\u00a0at UTSW resulted iin improvements in interventions completed, a reduction in alerts requiring review, an increased total duration that selected antimicrobials were dosed appropriately, and improved pharmacist satisfaction.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ajhp\/zxaf071","type":"journal-article","created":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T21:11:13Z","timestamp":1742677873000},"page":"S2963-S2973","source":"Crossref","is-referenced-by-count":2,"title":["The impact of a customized electronic health record clinical decision support tool on pharmacist renal dosing interventions"],"prefix":"10.1093","volume":"82","author":[{"given":"Brandyn","family":"Wilcox","sequence":"first","affiliation":[{"name":"Department of Pharmacy, University of Texas Southwestern Medical Center , Dallas, TX ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Sanders","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Texas Southwestern Medical Center , Dallas, TX"},{"name":"Division of Infectious Diseases and Geographic Medicine, Department of Medicine, University of Texas Southwestern Medical Center , Dallas, TX ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candace","family":"Sutton","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Texas Southwestern Medical Center , Dallas, TX ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meagan","family":"Johns","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Texas Southwestern Medical Center , Dallas, TX ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,4,2]]},"reference":[{"issue":"9","key":"2025081819563050100_CIT0001","doi-asserted-by":"publisher","first-page":"e119","DOI":"10.1093\/ajhp\/zxad036","article-title":"Implementation of a clinical decision support alert to prevent use of intravenous \u03b2-blockers and nondihydropyridine calcium channel blockers in hospitalized patients with acute decompensated heart failure","volume":"80","author":"Okerberg","year":"2023","journal-title":"Am J Health-Syst Pharm"},{"issue":"1","key":"2025081819563050100_CIT0002","doi-asserted-by":"publisher","first-page":"e50","DOI":"10.2146\/ajhp150787","article-title":"Implementation of a 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