{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:13:00Z","timestamp":1787008380804,"version":"build-2736575974"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the impact of electronic health record\u2013integrated voice alerts on turnaround time for anticoagulation reversal agents across 6 hospitals within a health system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a quasi-experimental pre-post study evaluating implementation of voice alerts for 4 reversal agents. Voice alerts were triggered when an eligible order entered the pharmacist verification queue. Six hospitals transitioned to the system on a staggered schedule. Orders were categorized into pre- and postimplementation periods, each spanning 90 days. Time from order signing to verification and administration were measured. Data were stratified by hospital, shift, and medication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 341 orders were analyzed, with 209 in the preimplementation period and 132 in the postimplementation period. During the postimplementation period, verification time decreased by 21.6% (P = 0.05) and administration time decreased by 20.8% (P &amp;lt; 0.01). Four out of 6 hospitals saw improvement in both verification and administration times. The largest turnaround time gains were for 4-factor prothrombin complex concentrate (4FPCC), which accounted for 73.3% of all orders. The largest verification time decrease (33.6%, P = 0.02) occurred during the night shift.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Voice alerts reduced turnaround time for high-priority anticoagulation reversal agents. The alerts were most impactful for 4FPCC and during the night shift, without requiring changes to existing pharmacy workflows. Site-specific implementation and alert routing were important in determining overall impact.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ajhp\/zxaf348","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T12:55:41Z","timestamp":1765976141000},"page":"652-660","source":"Crossref","is-referenced-by-count":1,"title":["Integration of voice alerts to improve turnaround time for anticoagulation reversal"],"prefix":"10.1093","volume":"83","author":[{"given":"Akraam","family":"Abdel-Kerem","sequence":"first","affiliation":[{"name":"Houston Methodist , Houston, TX ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Njigha","sequence":"additional","affiliation":[{"name":"Houston Methodist , Houston, TX ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niha","family":"Zafar","sequence":"additional","affiliation":[{"name":"Houston Methodist , Houston, TX 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