{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:13:01Z","timestamp":1787008381440,"version":"build-2736575974"},"reference-count":129,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Lung biopsy has traditionally played a fundamental role in addressing diagnostic uncertainty and guiding management of fibrotic interstitial lung disease (fILD). Multiple lung biopsy procedures are available for evaluating fILD, including bronchoscopic techniques such as transbronchial biopsy and transbronchial lung cryobiopsy, as well as surgical lung biopsy, which is now almost exclusively conducted using minimally invasive video-assisted thoracoscopic surgery. The various evolving \u00adconsiderations for and against lung biopsy have led to substantial ambiguity regarding the optimal timing and choice of biopsy method. The rationale for performing a lung biopsy in fILD is multifaceted, shaped by its potential to enhance diagnostic confidence and inform therapeutic decisions, weighed against procedural risks, and further nuanced by patient values and preferences. The objective of this state-of-the-art document from a multidisciplinary group of experts and patient representatives is to summarize the rationale for and against lung biopsy in the evaluation and management of fILD. Amid ongoing technological innovations, we further emphasize that future research should prioritize the development and validation of minimally invasive and noninvasive modalities that may serve as either alternatives or adjuncts to biopsy in the diagnostic evaluation of fILD.<\/jats:p>","DOI":"10.1093\/ajrccm\/aamaf123","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T12:45:30Z","timestamp":1767789930000},"page":"571-590","source":"Crossref","is-referenced-by-count":3,"title":["Clinical utility of lung biopsy in fibrotic interstitial lung disease"],"prefix":"10.1093","volume":"212","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5630-3498","authenticated-orcid":false,"given":"Elad","family":"Mor","sequence":"first","affiliation":[{"name":"Department of Medicine and Centre for Heart Lung Innovation, University of British Columbia , Vancouver, British Columbia,","place":["Canada"]},{"name":"Pulmonary Institute, Rambam Health Care Campus , Haifa,","place":["Israel"]},{"name":"Ruth and Bruce Rappaport Faculty of Medicine, The Technion\u2014Israel Institute of Technology , Haifa,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6608-0574","authenticated-orcid":false,"given":"Sara","family":"Piciucchi","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences (DIMEC), University of Bologna , Bologna,","place":["Italy"]},{"name":"Department of Radiology, GB Morgagni\u2014L.Pierantoni Hospital , Forl\u00ec,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Ravaglia","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences (DIMEC), University of Bologna , Bologna,","place":["Italy"]},{"name":"Department of Medical Specialities, Pulmonology Unit, GB Morgagni\u2014L. 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