{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:08:32Z","timestamp":1788199712707,"version":"build-2803163510"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2020,6,13]],"date-time":"2020-06-13T00:00:00Z","timestamp":1592006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Catholic University of Rome"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>People experiencing homelessness are often excluded from treatment programs for alcohol use disorder (AUD). The goal of this study was to describe the impact of a multidisciplinary treatment program on alcohol consumption and social reintegration in individuals with AUD experiencing homelessness.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Thirty-one individuals with AUD experiencing homelessness were admitted to an inpatient unit for 5\u20136\u00a0days for clinical evaluation and to treat potential alcohol withdrawal syndrome. A group of volunteers, in collaboration with the Community of Sant\u2019Egidio, provided social support aimed to reintegrate patients. After inpatient discharge, all patients were followed as outpatients. Alcohol intake (number drinks\/day), craving and clinical evaluation were assessed at each outpatient visit. Biological markers of alcohol use were evaluated at enrollment (T0), at 6\u00a0months (T1) and 12\u00a0months (T2).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Compared with T0, patients at T1 showed a significant reduction in alcohol consumption [10 (3\u201324) vs 2 (0\u201310); P\u00a0=\u00a00.015] and in \u03b3-glutamyl-transpeptidase [187 (78\u2013365) vs 98 (74\u2013254); P\u00a0=\u00a00.0021]. The reduction in alcohol intake was more pronounced in patients with any housing condition [10 (3\u201320) vs 1 (0\u20138); P\u00a0=\u00a00.008]. Similarly, compared with T0, patients at T2 showed significant reduction in alcohol consumption [10 (3\u201324) vs 0 (0\u201315); P\u00a0=\u00a00.001], more pronounced in patients with any housing condition [10 (3\u201320) vs 0 (0\u20132); P\u00a0=\u00a00.006]. Moreover, at T2 patients showed a significant reduction in \u03b3-glutamyl-transpeptidase [187 (78\u2013365) vs 97 (74\u2013189); P\u00a0=\u00a00.002] and in mean cell volume [100.2 (95\u2013103.6) vs 98.3 (95\u2013102); P\u00a0=\u00a00.042].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Patients experiencing homelessness may benefit from a multidisciplinary treatment program for AUD. Strategies able to facilitate and support their social reintegration and housing can improve treatment outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/alcalc\/agaa052","type":"journal-article","created":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T19:23:01Z","timestamp":1589397781000},"page":"547-553","source":"Crossref","is-referenced-by-count":9,"title":["Make Mission Impossible Feasible: The Experience of a Multidisciplinary Team Providing Treatment for Alcohol Use Disorder to Homeless Individuals"],"prefix":"10.1093","volume":"55","author":[{"given":"Tommaso","family":"Dionisi","sequence":"first","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Mosoni","sequence":"additional","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Di Sario","sequence":"additional","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Tarli","sequence":"additional","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariangela","family":"Antonelli","sequence":"additional","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Sestito","sequence":"additional","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"D\u2019Addio","sequence":"additional","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Tosoni","sequence":"additional","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Ferrarese","sequence":"additional","affiliation":[{"name":"Internal Medicine and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Iasilli","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy"},{"name":"Comunity of Sant\u2019Egidio, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele A","family":"Vassallo","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Barone Lombardo Hospital, Canicatt\u00ec, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3932-3803","authenticated-orcid":false,"given":"Antonio","family":"Mirijello","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo Emberti","family":"Gialloreti","sequence":"additional","affiliation":[{"name":"Comunity of Sant\u2019Egidio, Rome, Italy"},{"name":"Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Di Giuda","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Universitario A. 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