{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:49:54Z","timestamp":1791668994853,"version":"4.3.4"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,3,16]],"date-time":"2024-03-16T00:00:00Z","timestamp":1710547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R01AA026086"],"award-info":[{"award-number":["R01AA026086"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["T32HL116271"],"award-info":[{"award-number":["T32HL116271"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Department of Veterans Affairs or the US Government"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>This matched case\u2013control study aimed to provide epidemiologic evidence of increased burden of respiratory symptoms and pulmonary function decline among people living with human immunodeficiency virus (HIV) and a history of heavy alcohol consumption.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Cases were participants with HIV (PWH; n\u2009=\u200975, 33%), and controls were participants without HIV (PWoH; n\u2009=\u2009150, 67%). PWH were matched to PWoH by age and sex in the ratio of 1:2. Eligible participants responded to the respiratory health National Health and Nutrition Examination Survey questionnaire [prolonged coughs (\u22653\u00a0months), bringing up of phlegm (\u22653\u00a0months), and a history of wheezing or whistling in the chest (past year)]. The effects of both alcohol and HIV on participants\u2019 pulmonary function were determined using linear regression analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>History of heavy alcohol consumption was more prevalent among PWH (40%) compared to PWoH (27%). PWH who had a history of heavy alcohol consumption had a higher prevalence of coughing most days (45% vs. 4%, P\u2009=\u2009.0010), bringing up phlegm most days (31% vs. 0%, P\u2009=\u2009.0012), and wheezing or whistling in the chest (40% vs. 20%, P\u2009=\u2009.058) compared to participants who did not heavily consume alcohol. Furthermore, a history of heavy alcohol consumption was associated with decreased forced expiratory volume (ml) in 1\u00a0s\/forced vital capacity among PWH (\u03b2\u2009=\u2009\u2212 0.098 95% C.I. \u22120.16, \u22120.04, P\u2009=\u2009.03) after adjusting for having smoked at least 100 cigarettes in life.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>A history of heavy alcohol use increased respiratory symptoms and suppressed pulmonary function among people living with HIV. This study provides epidemiological evidence of the respiratory symptom burden of people living with HIV who have a history of heavy alcohol consumption.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/alcalc\/agae021","type":"journal-article","created":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T06:17:47Z","timestamp":1712384267000},"source":"Crossref","is-referenced-by-count":4,"title":["Pulmonary symptoms associated with heavy alcohol consumption among people living with HIV: an analysis of the NHANES 1999\u20132010"],"prefix":"10.1093","volume":"59","author":[{"given":"Moses","family":"New-Aaron","sequence":"first","affiliation":[{"name":"Division of Pulmonary , Allergy, Critical Care and Sleep Medicine, Department of Medicine, , 615 Michael St. (Suite 205), Atlanta, GA 30322 , United States of America"},{"name":"Emory University , Allergy, Critical Care and Sleep Medicine, Department of Medicine, , 615 Michael St. (Suite 205), Atlanta, GA 30322 , United States of America"},{"name":"Atlanta Veterans Affairs Health Care System , 1670 Clairmont Rd. (12C-191), Decatur, GA 30033 , United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohleen","family":"Kang","sequence":"additional","affiliation":[{"name":"Division of Pulmonary , Allergy, Critical Care and Sleep Medicine, Department of Medicine, , 615 Michael St. (Suite 205), Atlanta, GA 30322 , United States of America"},{"name":"Emory University , Allergy, Critical Care and Sleep Medicine, Department of Medicine, , 615 Michael St. (Suite 205), Atlanta, GA 30322 , United States of America"},{"name":"Atlanta Veterans Affairs Health Care System , 1670 Clairmont Rd. (12C-191), Decatur, GA 30033 , United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha M","family":"Yeligar","sequence":"additional","affiliation":[{"name":"Division of Pulmonary , Allergy, Critical Care and Sleep Medicine, Department of Medicine, , 615 Michael St. (Suite 205), Atlanta, GA 30322 , United States of America"},{"name":"Emory University , Allergy, Critical Care and Sleep Medicine, Department of Medicine, , 615 Michael St. (Suite 205), Atlanta, GA 30322 , United States of America"},{"name":"Atlanta Veterans Affairs Health Care System , 1670 Clairmont Rd. 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