{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:15:17Z","timestamp":1791216917558,"version":"4.1.0"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,1,1]]},"DOI":"10.1093\/alcalc\/agt169","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T02:11:12Z","timestamp":1384395072000},"page":"79-83","source":"Crossref","is-referenced-by-count":47,"title":["Self-Intoxication with Baclofen in Alcohol-Dependent Patients with Co-existing Psychiatric Illness: An Emergency Department Case Series"],"prefix":"10.1093","volume":"49","author":[{"given":"Nicolas","family":"Franchitto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Pelissier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Lauque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Lan\u00e7on","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,11,12]]},"reference":[{"key":"key\n\t\t\t\t20171010170354_AGT169C1","first-page":"67","article-title":"Ability of baclofen in reducing alcohol craving and intake: II\u2014Preliminary clinical evidence","volume":"24","author":"Addolorato","year":"2000","journal-title":"Alcohol Clin Exp Res"},{"key":"key\n\t\t\t\t20171010170354_AGT169C2","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/S0002-9343(01)01088-9","article-title":"Rapid suppression of alcohol withdrawal syndrome by baclofen","volume":"112","author":"Addolorato","year":"2002","journal-title":"Am J Med"},{"key":"key\n\t\t\t\t20171010170354_AGT169C3","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/alcalc\/agh130","article-title":"Complete and prolonged suppression of symptoms and consequences of alcohol-dependence using high-dose baclofen: a self-case report of a physician","volume":"40","author":"Ameisen","year":"2005","journal-title":"Alcohol Alcohol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C4","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.eurpsy.2009.11.007","article-title":"The role of alcohol use disorder and alcohol consumption in suicide attempts\u2014a secondary analysis of 1921 suicide attempts","volume":"25","author":"Boenisch","year":"2010","journal-title":"Eur Psychiatry"},{"key":"key\n\t\t\t\t20171010170354_AGT169C5","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1067\/mem.2002.122058","article-title":"The role of activated charcoal and gastric emptying in gastrointestinal decontamination: a state-of-the-art review","volume":"39","author":"Bond","year":"2002","journal-title":"Ann Emerg Med"},{"key":"key\n\t\t\t\t20171010170354_AGT169C6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1054-3589(10)58001-3","article-title":"Historical perspective and emergence of the GABAB receptor","volume":"58","author":"Bowery","year":"2010","journal-title":"Adv Pharmacol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C7","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1176\/ajp.146.3.353","article-title":"Role of gamma-aminobutyric acid in antipanic drug efficacy","volume":"146","author":"Breslow","year":"1989","journal-title":"Am J Psychiatry"},{"key":"key\n\t\t\t\t20171010170354_AGT169C8","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1093\/alcalc\/agl091","article-title":"Suppression of symptoms of alcohol dependence and craving using high-dose baclofen","volume":"42","author":"Bucknam","year":"2007","journal-title":"Alcohol Alcohol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C9","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0735-6757(96)90140-0","article-title":"Flumazenil-induced seizure accompanying benzodiazepine and baclofen intoxication","volume":"14","author":"Chern","year":"1996","journal-title":"Am J Emerg Med"},{"key":"key\n\t\t\t\t20171010170354_AGT169C10","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0735-6757(86)80018-3","article-title":"Atropine in the treatment of baclofen overdose","volume":"4","author":"Cohen","year":"1986","journal-title":"Am J Emerg Med"},{"key":"key\n\t\t\t\t20171010170354_AGT169C11","first-page":"361","article-title":"Alcohol and psychiatric comorbidity","volume":"16","author":"Cornelius","year":"2003","journal-title":"Recent Dev Alcohol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C12","doi-asserted-by":"crossref","first-page":"799","DOI":"10.2165\/00002018-200427110-00004","article-title":"A benefit-risk assessment of baclofen in severe spinal spasticity","volume":"27","author":"Dario","year":"2004","journal-title":"Drug Saf"},{"key":"key\n\t\t\t\t20171010170354_AGT169C13","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S0379-0738(01)00512-6","article-title":"Death due to baclofen and dipyrone ingestion","volume":"123","author":"De Giovanni","year":"2001","journal-title":"Forensic Sci Int"},{"key":"key\n\t\t\t\t20171010170354_AGT169C14","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1093\/alcalc\/agr131","article-title":"Clinical experience with baclofen in the management of alcohol-dependent patients with psychiatric comorbidity: a selected case series","volume":"46","author":"Dore","year":"2011","journal-title":"Alcohol Alcohol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C15","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1345\/aph.1C465","article-title":"Baclofen treatment for chronic posttraumatic stress disorder","volume":"37","author":"Drake","year":"2003","journal-title":"Ann Pharmacother"},{"key":"key\n\t\t\t\t20171010170354_AGT169C46","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1530-0277.2008.00805.x","article-title":"Acute interaction of baclofen in combination with alcohol in heavy social drinkers","volume":"33","author":"Evans","year":"2009","journal-title":"Alcohol Clin Exp Res"},{"key":"key\n\t\t\t\t20171010170354_AGT169C16","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1080\/10826080802344849","article-title":"The role of alcohol use in emergency department episodes","volume":"43","author":"French","year":"2008","journal-title":"Subst Use Misuse"},{"key":"key\n\t\t\t\t20171010170354_AGT169C17","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.neuroscience.2011.09.043","article-title":"GABA(B) receptors accentuate neural excitation contrast in rat insular cortex","volume":"199","author":"Fujita","year":"2011","journal-title":"Neuroscience"},{"key":"key\n\t\t\t\t20171010170354_AGT169C18","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1111\/j.1530-0277.2010.01273.x","article-title":"Efficacy and safety of baclofen for alcohol dependence: a randomized, double-blind, placebo-controlled trial","volume":"34","author":"Garbutt","year":"2010","journal-title":"Alcohol Clin Exp Res"},{"key":"key\n\t\t\t\t20171010170354_AGT169C19","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S0196-0644(86)80388-2","article-title":"First-order elimination kinetics following baclofen overdose","volume":"15","author":"Gerkin","year":"1986","journal-title":"Ann Emerg Med"},{"key":"key\n\t\t\t\t20171010170354_AGT169C20","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1080\/08897077.2012.663326","article-title":"Is baclofen a revolutionary medication in alcohol addiction management? Review and recent updates","volume":"33","author":"Gorsane","year":"2012","journal-title":"Subst Abus"},{"key":"key\n\t\t\t\t20171010170354_AGT169C21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3109\/15563658308990050","article-title":"Baclofen (Lioresal) intoxication report of 4 cases and review of the literature","volume":"20","author":"Haubenstock","year":"1983","journal-title":"J Toxicol Clin Toxicol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C22","doi-asserted-by":"crossref","first-page":"775","DOI":"10.4088\/JCP.10m06320","article-title":"Alcohol use disorders in schizophrenia: a national cohort study of 12,653 patients","volume":"72","author":"Jones","year":"2011","journal-title":"J Clin Psychiatry"},{"key":"key\n\t\t\t\t20171010170354_AGT169C23","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1001\/archpsyc.1997.01830160031005","article-title":"Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey","volume":"54","author":"Kessler","year":"1997","journal-title":"Arch Gen Psychiatry"},{"key":"key\n\t\t\t\t20171010170354_AGT169C24","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.jemermed.2012.01.059","article-title":"A poison center's ten-year experience with flumazenil administration to acutely poisoned adults","volume":"43","author":"Kreshak","year":"2012","journal-title":"J Emerg Med"},{"key":"key\n\t\t\t\t20171010170354_AGT169C25","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.addbeh.2011.12.010","article-title":"Baclofen promotes alcohol abstinence in alcohol dependent cirrhotic patients with hepatitis C virus (HCV) infection","volume":"37","author":"Leggio","year":"2012","journal-title":"Addict Behav"},{"key":"key\n\t\t\t\t20171010170354_AGT169C26","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1080\/13811110701800699","article-title":"Characteristics of suicide attempts preceded by alcohol consumption","volume":"12","author":"Lejoyeux","year":"2008","journal-title":"Arch Suicide Res"},{"key":"key\n\t\t\t\t20171010170354_AGT169C27","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1742-6723.2006.00805.x","article-title":"Baclofen overdose: defining the spectrum of toxicity","volume":"18","author":"Leung","year":"2006","journal-title":"Emerg Med Australas"},{"key":"key\n\t\t\t\t20171010170354_AGT169C28","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.clinre.2011.01.019","article-title":"Baclofen-induced acute hepatitis in alcohol-dependent patient","volume":"35","author":"Macaigne","year":"2011","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C29","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.4088\/JCP.v68n0802","article-title":"Adherence to pharmacotherapy in bipolar disorder patients with and without co-occurring substance use disorders","volume":"68","author":"Manwani","year":"2007","journal-title":"J Clin Psychiatry"},{"key":"key\n\t\t\t\t20171010170354_AGT169C30","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1542\/peds.101.6.1045","article-title":"Baclofen overdose: drug experimentation in a group of adolescents","volume":"101","author":"Perry","year":"1998","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20171010170354_AGT169C31","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1093\/qjmed\/93.5.291","article-title":"The burden of alcohol misuse on an inner-city general hospital","volume":"93","author":"Pirmohamed","year":"2000","journal-title":"QJM"},{"key":"key\n\t\t\t\t20171010170354_AGT169C32","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.psychres.2011.04.030","article-title":"Comorbid anxiety disorders and baseline medication regimens predict clinical outcomes in individuals with co-occurring bipolar disorder and alcohol dependence: Results of a randomized controlled trial","volume":"188","author":"Prisciandaro","year":"2011","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t20171010170354_AGT169C33","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1001\/jama.1990.03450190043026","article-title":"Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study","volume":"264","author":"Regier","year":"1990","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20171010170354_AGT169C47","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/alcalc\/ags028","article-title":"Abstinence and \u2018low-risk\u2019 consumption 1 year after the initiation of high-dose baclofen: a retrospective study among \u2018high-risk\u2019 drinkers","volume":"47","author":"Rigal","year":"2012","journal-title":"Alcohol Alcohol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C34","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1111\/j.1360-0443.2011.03752.x","article-title":"Alcohol-dependence: the current French craze for baclofen","volume":"107","author":"Rolland","year":"2012","journal-title":"Addiction"},{"key":"key\n\t\t\t\t20171010170354_AGT169C35","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/alcalc\/ags076","article-title":"A case of de novo seizures following a probable interaction of high-dose baclofen with alcohol","volume":"47","author":"Rolland","year":"2012","journal-title":"Alcohol Alcohol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C36","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0165-0327(02)00173-8","article-title":"Distal risk factors for suicidal behavior in alcoholics: replications and new findings","volume":"77","author":"Roy","year":"2003","journal-title":"J Affect Disord"},{"key":"key\n\t\t\t\t20171010170354_AGT169C37","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1080\/13811110701250150","article-title":"Risk factors for suicide attempts among alcohol dependent patients","volume":"11","author":"Roy","year":"2007","journal-title":"Arch Suicide Res"},{"key":"key\n\t\t\t\t20171010170354_AGT169C38","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1097\/00000542-199206000-00027","article-title":"Flumazenil counteracts intrathecal baclofen-induced central nervous system depression in tetanus","volume":"76","author":"Saissy","year":"1992","journal-title":"Anesthesiology"},{"key":"key\n\t\t\t\t20171010170354_AGT169C39","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3109\/15563650.2011.654209","article-title":"Baclofen overdose mimicking brain death","volume":"50","author":"Sullivan","year":"2012","journal-title":"Clin Toxicol"},{"key":"key\n\t\t\t\t20171010170354_AGT169C40","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/S0736-4679(99)00129-8","article-title":"Baclofen and ethanol ingestion: a case report","volume":"17","author":"VanDierendonk","year":"1999","journal-title":"J Emerg Med"},{"key":"key\n\t\t\t\t20171010170354_AGT169C41","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1136\/emj.2010.095075","article-title":"Flumazenil use in benzodiazepine overdose in the UK: a retrospective survey of NPIS data","volume":"29","author":"Veiraiah","year":"2012","journal-title":"Emerg Med J"},{"key":"key\n\t\t\t\t20171010170354_AGT169C42","doi-asserted-by":"crossref","first-page":"611","DOI":"10.4037\/ajcc2006.15.6.611","article-title":"An initially unsuspected case of baclofen overdose","volume":"15","author":"Wall","year":"2006","journal-title":"Am J Crit Care"},{"key":"key\n\t\t\t\t20171010170354_AGT169C43","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2165\/00002018-199717030-00004","article-title":"A risk-benefit assessment of flumazenil in the management of benzodiazepine overdose","volume":"17","author":"Weinbroum","year":"1997","journal-title":"Drug Saf"},{"key":"key\n\t\t\t\t20171010170354_AGT169C44","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1007\/s00431-012-1780-y","article-title":"Baclofen intoxication: a \u2018fun drug\u2019 causing deep coma and nonconvulsive status epilepticus-a case report and review of the literature","volume":"171","author":"Wei\u00dfhaar","year":"2012","journal-title":"Eur J Pediatr"},{"key":"key\n\t\t\t\t20171010170354_AGT169C45","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1553-2712.2000.tb01884.x","article-title":"Alcoholism in the emergency department: an epidemiologic study","volume":"7","author":"Whiteman","year":"2000","journal-title":"Acad Emerg Med"}],"container-title":["Alcohol and Alcoholism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/alcalc\/article-pdf\/49\/1\/79\/338970\/agt169.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T22:38:02Z","timestamp":1596839882000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/alcalc\/article\/49\/1\/79\/145500\/SelfIntoxication-with-Baclofen-in-AlcoholDependent"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,12]]},"references-count":47,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,11,12]]},"published-print":{"date-parts":[[2014,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/alcalc\/agt169","relation":{},"ISSN":["1464-3502","0735-0414"],"issn-type":[{"value":"1464-3502","type":"electronic"},{"value":"0735-0414","type":"print"}],"subject":[],"published-other":{"date-parts":[[2014,1]]},"published":{"date-parts":[[2013,11,12]]}}}