{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:43:17Z","timestamp":1790786597271,"version":"4.1.0"},"reference-count":56,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T00:00:00Z","timestamp":1570752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Psychotic symptoms can occur in the general population, and alcohol use disorder (AUD) is an identified vulnerability factor. However, it remains unclear how AUD is associated with psychotic symptoms, depending on the underlying psychiatric condition.<\/jats:p>\n                  <jats:p>We aimed to compare the prevalence of psychotic symptoms among subjects with different types of psychiatric disorders, i.e. unipolar or bipolar disorders, anxiety disorders, psychotic disorders or no psychiatric disorder, depending on whether or not there was an underlying AUD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In a 38,694-subject general population study, we compared the likelihood of occurrence of seven types of psychotic symptoms, depending on the AUD status and the underlying psychiatric disorders, after adjustment for age, sex, marital status, education and income levels.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In unipolar depression and anxiety disorders, almost all types of psychotic symptoms were found associated with AUD (odds ratios (ORs) between 1.98 and 2.19). In contrast, in bipolar disorder, only auditory hallucinations were associated with AUD (OR\u00a0=\u00a02.50). In psychotic disorders, only thought broadcasting was more frequent among subjects with AUD (OR\u00a0=\u00a01.78).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our findings in depression and anxiety disorders are in line with the \u2018dual diagnosis\u2019 concept, which posits that comorbid psychiatric\/addictive disorders form distinctive entities that are more frequently associated with non-specific severity factors, here psychotic symptoms. The co-occurrence of AUD in bipolar\/psychotic disorders was not associated with a generalized increased occurrence of psychotic symptoms but altered their manifestations with an increased risk of auditory hallucinations for bipolar disorder and thought broadcasting for psychotic disorders.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/alcalc\/agz077","type":"journal-article","created":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T11:36:37Z","timestamp":1566473797000},"source":"Crossref","is-referenced-by-count":6,"title":["Alcohol Use Disorder Is Differently Associated With Psychotic Symptoms According To Underlying Psychiatric Disorders: A General Population Study"],"prefix":"10.1093","author":[{"given":"Baptiste","family":"Pignon","sequence":"first","affiliation":[{"name":"AP-HP, DHU PePSY, H\u00f4pitaux Universitaires Henri-Mondor, P\u00f4le de Psychiatrie; Inserm, U955, Team 15; Fondation FondaMental and UPEC, Universit\u00e9 Paris-Est, Facult\u00e9 de m\u00e9decine, 51 avenue du Mar\u00e9chal Delattre de Tassigny, 94000 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Sescousse","sequence":"additional","affiliation":[{"name":"Service Universitaire d\u2019Addictologie de Lyon (SUAL), CH Le Vinatier; Univ Lyon, UCBL, Inserm U1028, CNRS UMR5292, CRNL, PSYR2, 95 Bd Pinel, Bron F-69500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Amad","sequence":"additional","affiliation":[{"name":"Univ. Lille, CNRS UMR 9193-PsyCHIC-SCALab, & CHU Lille, P\u00f4le de Psychiatrie, Unit\u00e9 CURE, Lille F-59000, France"},{"name":"F\u00e9d\u00e9ration R\u00e9gionale de Recherche en Sant\u00e9 Mentale (F2RSM) Hauts-de-France, rue Andr\u00e9 Verhaeghe, Lille F-59000, France"},{"name":"King's College London, Institute of Psychiatry, Psychology and Neuroscience, 16 De Crespigny Park, Camberwell, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imane","family":"Benradia","sequence":"additional","affiliation":[{"name":"EPSM Lille M\u00e9tropole; Centre Collaborateur de l\u2019Organisation Mondiale de la Sant\u00e9 pour la Recherche et la Formation en Sant\u00e9 Mentale; \u00c9quipe Eceve Inserm UMR 1123, 211 rue Roger Salengro, F-59 260 Hellemmes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Vaiva","sequence":"additional","affiliation":[{"name":"Univ. Lille, CNRS UMR 9193-PsyCHIC-SCALab, & CHU Lille, P\u00f4le de Psychiatrie, Unit\u00e9 CURE, Lille F-59000, France"},{"name":"F\u00e9d\u00e9ration R\u00e9gionale de Recherche en Sant\u00e9 Mentale (F2RSM) Hauts-de-France, rue Andr\u00e9 Verhaeghe, Lille F-59000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Thomas","sequence":"additional","affiliation":[{"name":"Univ. Lille, CNRS UMR 9193-PsyCHIC-SCALab, & CHU Lille, P\u00f4le de Psychiatrie, Unit\u00e9 CURE, Lille F-59000, France"},{"name":"F\u00e9d\u00e9ration R\u00e9gionale de Recherche en Sant\u00e9 Mentale (F2RSM) Hauts-de-France, rue Andr\u00e9 Verhaeghe, Lille F-59000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre A","family":"Geoffroy","sequence":"additional","affiliation":[{"name":"Inserm, U1144, F-75006; Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9, UMR-S 1144, F-75013; AP-HP, GH Saint-Louis \u2013 Lariboisi\u00e8re \u2013 F. Widal, P\u00f4le de Psychiatrie et de M\u00e9decine Addictologique, 200 Rue du Faubourg Saint-Denis, F-75475, Paris cedex 10 75475 and Fondation FondaMental, Cr\u00e9teil 94000, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Roelandt","sequence":"additional","affiliation":[{"name":"EPSM Lille M\u00e9tropole; Centre Collaborateur de l\u2019Organisation Mondiale de la Sant\u00e9 pour la Recherche et la Formation en Sant\u00e9 Mentale; \u00c9quipe Eceve Inserm UMR 1123, 211 rue Roger Salengro, F-59 260 Hellemmes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8666-3635","authenticated-orcid":false,"given":"Benjamin","family":"Rolland","sequence":"additional","affiliation":[{"name":"Service Universitaire d\u2019Addictologie de Lyon (SUAL), CH Le Vinatier; Univ Lyon, UCBL, Inserm U1028, CNRS UMR5292, CRNL, PSYR2, 95 Bd Pinel, Bron F-69500, 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