{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:32:38Z","timestamp":1787671958126,"version":"build-2736575974"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Lung cancer screening (LCS) with annual low-dose CT reduces mortality, but benefit depends on timely adherence to annual screening. Language barriers may introduce additional challenges to screening adherence. We examined the association between non-English language preference and annual adherence to LCS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study of LCS-eligible adults who underwent initial screening between January 1, 2015, and March 10, 2025, within a four-hospital regional health system serving a diverse urban and rural population in Massachusetts. The primary outcome was receipt of timely follow-up screening within the recommended 10\u201315-month interval across up to three subsequent annual screenings. The primary exposure was preferred language (non-English vs. English). We employed generalized estimating equation models with logit link, adjusting for age, sex, comorbidities, neighborhood deprivation, and screening round. Patients with Lung-RADS 3 or 4 results, death, or who reached age 80 between screening rounds were censored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 7,218 patients (mean age 62.6 \u00b1 5.8 years; 48.8% female), 92.9% preferred English and 7.1% non-English. Non-English speakers were more frequently Hispanic (77.7% vs. 4.5%) and had higher prevalence of comorbidities and neighborhood disadvantage. After the initial screen, 59.6% completed follow-up within 10\u201315 months and 21.1% had no follow-up. Overall, 26.5% of the cohort completed all three follow-up scans within the recommended interval. Non-English speakers were less likely to complete screening within the recommended interval at every screening round (T1: 51.4% vs. 60.2%; T2: 57.5% vs. 64.8%; T3: 52.5% vs. 60.6%) and more likely to have no follow-up at each interval. Non-English language preference was independently associated with lower odds of completing timely annual screens (adjusted OR 0.79; 95% CI 0.66\u20130.95), with findings consistent in sensitivity analyses using inverse probability of censoring weighting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this large community-based LCS cohort, non-English language preference was independently associated with 21% lower odds of timely annual screening adherence after adjustment for comorbidities and socioeconomic factors. Linguistically tailored outreach, patient education, and navigation support are critical to advancing equitable lung cancer screening.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/annalsats\/aaoag260","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:10:51Z","timestamp":1787670651000},"source":"Crossref","is-referenced-by-count":0,"title":["Language Preference Associated with Disparities in Annual Lung Cancer Screening Adherence in an Integrated Healthcare System"],"prefix":"10.1093","author":[{"given":"Eduardo R","family":"N\u00fa\u00f1ez","sequence":"first","affiliation":[{"name":"University of Massachusetts Chan Medical School-Baystate Department of Healthcare Delivery and Population Sciences, , Springfield, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aruna","family":"Priya","sequence":"additional","affiliation":[{"name":"University of Massachusetts Chan Medical School-Baystate Department of Healthcare Delivery and Population Sciences, , Springfield, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viswanathan","family":"Shankar","sequence":"additional","affiliation":[{"name":"University of Massachusetts Chan Medical School-Baystate Department of Healthcare Delivery and Population Sciences, , Springfield, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose","family":"Ganim","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Massachusetts Chan Medical School-Baystate , Springfield, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence N","family":"Benjamin","sequence":"additional","affiliation":[{"name":"University of California Department of Medicine, David Geffen School of Medicine, , Los Angeles, Los Angeles, CA,","place":["USA"]},{"name":"VA Greater Los Angeles Healthcare System Center for the Study of Healthcare Innovation, Implementation, and Policy (CSHIIP), , Los Angeles, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa C","family":"Diamond","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center Departments of Psychiatry and Behavioral Sciences and Department of Medicine, , New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penelope","family":"Pekow","sequence":"additional","affiliation":[{"name":"University of Massachusetts Department of Biostatistics and Epidemiology, , Amherst, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renda Soylemez","family":"Wiener","sequence":"additional","affiliation":[{"name":"Center for Health Optimization & Implementation Research, VA Boston Healthcare System , Boston, MA"},{"name":"Veterans Health Administration National Center for Lung Cancer Screening, , Washington, DC"},{"name":"Boston University Chobanian & Avedisian School of Medicine The Pulmonary Center, , Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter K","family":"Lindenauer","sequence":"additional","affiliation":[{"name":"University of Massachusetts Chan Medical School-Baystate Department of Healthcare Delivery and Population Sciences, , Springfield, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,25]]},"container-title":["Annals of the American Thoracic Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/annalsats\/advance-article-pdf\/doi\/10.1093\/annalsats\/aaoag260\/70784342\/aaoag260.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/annalsats\/advance-article-pdf\/doi\/10.1093\/annalsats\/aaoag260\/70784342\/aaoag260.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:10:52Z","timestamp":1787670652000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/annalsats\/advance-article\/doi\/10.1093\/annalsats\/aaoag260\/8770360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,25]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/annalsats\/aaoag260","relation":{},"ISSN":["2325-6621"],"issn-type":[{"value":"2325-6621","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,25]]},"article-number":"aaoag260"}}