{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T10:53:35Z","timestamp":1782298415091,"version":"3.54.5"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T00:00:00Z","timestamp":1573516800000},"content-version":"vor","delay-in-days":2051,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Oncology"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1093\/annonc\/mdu031","type":"journal-article","created":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T10:38:42Z","timestamp":1395743922000},"page":"864-869","source":"Crossref","is-referenced-by-count":46,"title":["Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy"],"prefix":"10.1016","volume":"25","author":[{"given":"A.M.","family":"Kuijpers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Boot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.E.","family":"van Leerdam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hauptmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.G.","family":"Aalbers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.J.","family":"Verwaal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/annonc\/mdu031_bb0010","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.1002\/ijc.25596","article-title":"Predictors and survival of synchronous peritoneal carcinomatosis of colorectal origin: a population-based study","volume":"128","author":"Lemmens","year":"2011","journal-title":"Int J Cancer"},{"key":"10.1093\/annonc\/mdu031_bb0015","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1002\/bjs.8679","article-title":"Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer","volume":"99","author":"Segelman","year":"2012","journal-title":"Br J Surg"},{"key":"10.1093\/annonc\/mdu031_bb0020","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s10147-012-0505-6","article-title":"Outcomes of surgery without HIPEC for synchronous peritoneal metastasis from colorectal cancer: data from a multi-center registry","volume":"19","author":"Kobayashi","year":"2014","journal-title":"Int J Clin Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0025","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/(SICI)1097-0142(20000115)88:2<358::AID-CNCR16>3.0.CO;2-O","article-title":"Peritoneal carcinomatosis from non-gynecologic malignancies: results of the EVOCAPE 1 multicentric prospective study","volume":"88","author":"Sadeghi","year":"2000","journal-title":"Cancer"},{"key":"10.1093\/annonc\/mdu031_bb0030","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1200\/JCO.2011.37.1039","article-title":"Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841","volume":"30","author":"Franko","year":"2012","journal-title":"J Clin Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0035","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ejso.2012.03.008","article-title":"Outcomes of colorectal cancer patients with peritoneal carcinomatosis treated with chemotherapy with and without targeted therapy","volume":"38","author":"Klaver","year":"2012","journal-title":"Eur J Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0040","series-title":"Peritoneal Carcinomatosis","first-page":"425","article-title":"Systemic chemotherapy in patients with peritoneal carcinomatosis from colorectal cancer","author":"Folprecht","year":"2007"},{"key":"10.1093\/annonc\/mdu031_bb0045","doi-asserted-by":"crossref","first-page":"3737","DOI":"10.1200\/JCO.2003.04.187","article-title":"Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer","volume":"21","author":"Verwaal","year":"2003","journal-title":"J Clin Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0050","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1245\/s10434-008-9966-2","article-title":"8-year follow-up of randomized trial: cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy in patients with peritoneal carcinomatosis of colorectal cancer","volume":"15","author":"Verwaal","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0055","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1056\/NEJMoa032709","article-title":"Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer","volume":"350","author":"Andre","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1093\/annonc\/mdu031_bb0060","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1056\/NEJM199002083220602","article-title":"Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma","volume":"322","author":"Moertel","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1093\/annonc\/mdu031_bb0065","doi-asserted-by":"crossref","first-page":"321","DOI":"10.7326\/0003-4819-122-5-199503010-00001","article-title":"Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report","volume":"122","author":"Moertel","year":"1995","journal-title":"Ann Intern Med"},{"key":"10.1093\/annonc\/mdu031_bb0070","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1097\/SLA.0b013e3181d9765d","article-title":"A comparative study of complete cytoreductive surgery plus intraperitoneal chemotherapy to treat peritoneal dissemination from colon, rectum, small bowel, and nonpseudomyxoma appendix","volume":"251","author":"Elias","year":"2010","journal-title":"Ann Surg"},{"key":"10.1093\/annonc\/mdu031_bb0075","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1200\/JCO.2004.10.012","article-title":"Cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for the management of peritoneal carcinomatosis from colorectal cancer: a multi-institutional study","volume":"22","author":"Glehen","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0080","doi-asserted-by":"crossref","first-page":"5608","DOI":"10.1002\/cncr.25356","article-title":"Toward curative treatment of peritoneal carcinomatosis from nonovarian origin by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy: a multi-institutional study of 1,290 patients","volume":"116","author":"Glehen","year":"2010","journal-title":"Cancer"},{"key":"10.1093\/annonc\/mdu031_bb0085","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1245\/s10434-006-9185-7","article-title":"Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: a consensus statement. Society of Surgical Oncology","volume":"14","author":"Esquivel","year":"2007","journal-title":". Ann Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0090","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.1245\/s10434-013-3145-9","article-title":"Cytoreduction and HIPEC in the Netherlands: nationwide long-term outcome following the Dutch protocol","volume":"20","author":"Kuijpers","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0095","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1053\/ctrv.2001.0232","article-title":"Rationale and techniques of intra-operative hyperthermic intraperitoneal chemotherapy","volume":"27","author":"Witkamp","year":"2001","journal-title":"Cancer Treat Rev"},{"key":"10.1093\/annonc\/mdu031_bb0100","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.ejso.2009.02.010","article-title":"Quantitative intra-operative assessment of peritoneal carcinomatosis - a comparison of three prognostic tools","volume":"35","author":"Swellengrebel","year":"2009","journal-title":"Eur J Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0105","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1002\/bjs.4516","article-title":"Predicting the survival of patients with peritoneal carcinomatosis of colorectal origin treated by aggressive cytoreduction and hyperthermic intraperitoneal chemotherapy","volume":"91","author":"Verwaal","year":"2004","journal-title":"Br J Surg"},{"key":"10.1093\/annonc\/mdu031_bb0110","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10434-004-1167-z","article-title":"Long-term survival of peritoneal carcinomatosis of colorectal origin","volume":"12","author":"Verwaal","year":"2005","journal-title":"Ann Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0115","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/jso.21057","article-title":"Morbidity, toxicity, and mortality classification systems in the local regional treatment of peritoneal surface malignancy","volume":"98","author":"Younan","year":"2008","journal-title":"J Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0120","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1245\/s10434-009-0487-4","article-title":"A systematic review and meta-analysis of cytoreductive surgery with perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis of colorectal origin","volume":"16","author":"Cao","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0125","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ejso.2004.10.005","article-title":"Surgical trauma and peritoneal recurrence of colorectal carcinoma","volume":"31","author":"Oosterling","year":"2005","journal-title":"Eur J Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0130","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/jso.20273","article-title":"Surgery promotes implantation of disseminated tumor cells, but does not increase growth of tumor cell clusters","volume":"92","author":"Raa","year":"2005","journal-title":"J Surg Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0135","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1159\/000107781","article-title":"The post-surgical inflammatory response provokes enhanced tumour recurrence: a crucial role for neutrophils","volume":"24","author":"van den Tol","year":"2007","journal-title":"Dig Surg"},{"key":"10.1093\/annonc\/mdu031_bb0140","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1007\/s11605-013-2295-1","article-title":"Safety and outcomes following resection of colorectal liver metastases in the era of current perioperative chemotherapy","volume":"17","author":"Gur","year":"2013","journal-title":"J Gastrointest Surg"},{"key":"10.1093\/annonc\/mdu031_bb0145","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/S1470-2045(13)70447-9","article-title":"Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial","volume":"14","author":"Nordlinger","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1093\/annonc\/mdu031_bb0150","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/SLA.0b013e318255486a","article-title":"Progression following neoadjuvant systemic chemotherapy may not be a contraindication to a curative approach for colorectal carcinomatosis","volume":"256","author":"Passot","year":"2012","journal-title":"Ann Surg"}],"container-title":["Annals of Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923753419365135?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923753419365135?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/annonc\/article-pdf\/25\/4\/864\/16703412\/mdu031.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T20:06:51Z","timestamp":1625170011000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923753419365135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S0923753419365135"],"URL":"https:\/\/doi.org\/10.1093\/annonc\/mdu031","relation":{},"ISSN":["0923-7534"],"issn-type":[{"value":"0923-7534","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]}}}