{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T06:53:33Z","timestamp":1775026413399,"version":"3.50.1"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:00:00Z","timestamp":1612828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Bioderma Laboratories Romania"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Workers in the healthcare sector are at high risk of developing occupational hand eczema mainly due to frequent exposure to irritants and\/or allergens. Amongst workers in healthcare, nurses are at higher risk of developing hand dermatitis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To evaluate the effectiveness of a short educational intervention program in preventing occupational hand eczema in nurse apprentices, using two objective tools, namely TEWL and EH, and the HECSI score.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Data regarding professions, wet work exposure, activities performed during working hours, self-reported eczema were collected from 230 nurse students, divided in two study groups: the intervention and the control group (CG). The intervention group (IG) was given education about risks and proper skin care and was provided with cosmeceuticals to be used for skin care during hospital activity. The evaluation of skin properties was performed using questionnaires, HECSI score, measurement of transepidermal water loss (TEWL) and epidermal hydration (EH).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A number of 139 apprentice nurses completed the study. Of those participants who completed the study, 19.1% from CG and 19.6% from IG reported, at T1, hand eczema in the last 3 months, while at T2 (3 months later), 59.52 % of the CG and only 11.34 % from the IG stated having eczema in the last 3 months. In the IG, results showed an improvement of CM with 17% and of TEWL with 16%, with only a 0.5% improvement of CM in CG and a marked impairment of TEWL by 33%.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Hand eczema is a common occupational dermatosis affecting the medical staff, even during apprenticeship. Early preventive training programs are effective in reducing the burden of occupational contact dermatitis.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/annweh\/wxaa122","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T12:11:15Z","timestamp":1605096675000},"page":"167-175","source":"Crossref","is-referenced-by-count":7,"title":["Prevention of Hand Eczema among Nurse Apprentice (PREVEDERM): An Interventional Study"],"prefix":"10.1093","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4441-7030","authenticated-orcid":false,"given":"Horatiu Remus","family":"Moldovan","sequence":"first","affiliation":[{"name":"Occupational Medicine Department, GE Palade University of Medicine, Pharmacy, Science and Technology of Targu-Mures, Gheorghe Marinescu, T\u00e2rgu Mure\u0219, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ionela","family":"Manole","sequence":"additional","affiliation":[{"name":"Dermatology Research Unit, Colentina Clinical Hospital, Stefan cel Mare, Bucharest, Romania"},{"name":"Carol Davila University of Medicine and Pharmacy, Eroii Sanitari, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alina","family":"Suru","sequence":"additional","affiliation":[{"name":"Dermatology Research Unit, Colentina Clinical Hospital, Stefan cel Mare, Bucharest, Romania"},{"name":"Carol Davila University of Medicine and Pharmacy, Eroii Sanitari, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra-Irina","family":"Butacu","sequence":"additional","affiliation":[{"name":"Dermatology Research Unit, Colentina Clinical Hospital, Stefan cel Mare, Bucharest, Romania"},{"name":"Carol Davila University of Medicine and Pharmacy, Eroii Sanitari, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4290-7068","authenticated-orcid":false,"given":"Alin Laurentiu","family":"Tatu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Dunarea de Jos University, Clinical Medical Department, Galati, Romania, Alexandru Ioan Cuza, Galati, Romania"},{"name":"Saint Parascheva Clinical Hospital of Infectious Diseases, Dermatology Department, Traian, Galati, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Lupu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, University Dunarea de Jos, Alexandru Ioan Cuza,Galati, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihai","family":"Dascalu","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Faculty of Automated Control and Computers, University Politehnica of Bucharest, Splaiul Independentei, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George-Sorin","family":"Tiplica","sequence":"additional","affiliation":[{"name":"Carol Davila University of Medicine and Pharmacy, Eroii Sanitari, Bucharest, Romania"},{"name":"Second Department of Dermatology, Colentina Clinical Hospital, Stefan cel Mare, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen Maria","family":"Salavastru","sequence":"additional","affiliation":[{"name":"Carol Davila University of Medicine and Pharmacy, Eroii Sanitari, Bucharest, Romania"},{"name":"Pediatric Dermatology Department, Colentina Clinical Hospital, Stefan cel Mare, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,2,9]]},"reference":[{"key":"2021122015113838600_CIT0001","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1111\/bjd.12256","article-title":"U.K. standards of care for occupational contact dermatitis and occupational contact urticaria","volume":"168","author":"Adisesh","year":"2013","journal-title":"Br J Dermatol"},{"key":"2021122015113838600_CIT0002","first-page":"1","article-title":"Noninvasive measuring methods for the investigation of irritant patch test reactions. A study of patients with hand eczema, atopic dermatitis and controls","volume":"173","author":"Agner","year":"1992","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"2021122015113838600_CIT0003","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/occmed\/kqu170","article-title":"A survey of occupational skin disease in UK health care workers","volume":"65","author":"Campion","year":"2015","journal-title":"Occup Med (Lond)"},{"key":"2021122015113838600_CIT0004","doi-asserted-by":"crossref","first-page":"102","DOI":"10.4103\/2229-5178.110629","article-title":"Impact of hand eczema severity on quality of life","volume":"4","author":"Charan","year":"2013","journal-title":"Indian Dermatol Online J"},{"key":"2021122015113838600_CIT0005","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1177\/0748233715584699","article-title":"Chromium-induced skin dam- age among Taiwanese cement workers","volume":"32","author":"Chou","year":"2016","journal-title":"Toxicol Indust Health"},{"key":"2021122015113838600_CIT0006","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/cod.12304","article-title":"Evidence-based training as primary prevention of hand eczema in a population of hospital cleaning workers","volume":"72","author":"Clemmensen","year":"2015","journal-title":"Contact Dermatitis"},{"key":"2021122015113838600_CIT0007","volume-title":"Occupational skin diseases and dermal exposure in the European Union (EU-25): policy and practice overview","author":"De Craecker","year":"2008"},{"key":"2021122015113838600_CIT0008"},{"key":"2021122015113838600_CIT0009","volume-title":"List of tools for intervention studies: COST Action TD1206 StanDerm Working Group 3 Scores for assessment of prevalence and severity of hand eczema (review [1])","author":"Development and Implementation of European Standards on Prevention of Occupational Skin Diseases (StanDerm)"},{"key":"2021122015113838600_CIT0010","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1007\/s004200050407","article-title":"The epidemiology of occupational contact dermatitis","volume":"72","author":"Diepgen","year":"1999","journal-title":"Int Arch Occup Environ Health"},{"key":"2021122015113838600_CIT0011","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1136\/oem.59.8.556","article-title":"Prevention of work related skin problems: an intervention study in wet work employees","volume":"59","author":"Held","year":"2002","journal-title":"Occup Environ Med"},{"key":"2021122015113838600_CIT0012","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1365-2133.2004.06305.x","article-title":"The Hand Eczema Severity Index (HECSI): a scoring system for clinical assessment of hand eczema. A study of inter- and intraobserver reliability","volume":"152","author":"Held","year":"2005","journal-title":"Br J Dermatol"},{"key":"2021122015113838600_CIT0013","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1093\/occmed\/kqs115","article-title":"Workers with occupational contact dermatitis: workplace characteristics and prevention practices","volume":"62","author":"Holness","year":"2012","journal-title":"Occup Med (Lond)"},{"key":"2021122015113838600_CIT0014"},{"key":"2021122015113838600_CIT0015","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/srt.12711","article-title":"Measurement of transepidermal water loss, stratum corneum hydration and skin surface pH in occupational settings: a review","volume":"25","author":"Jansen van Rensburg","year":"2019","journal-title":"Skin Res Technol"},{"key":"2021122015113838600_CIT0016","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1600-0536.2010.01706.x","article-title":"Non-invasive bioengineering methods in an intervention study in 1020 male metal workers: results and implications for occupational dermatology","volume":"62","author":"K\u00fctting","year":"2010","journal-title":"Contact Dermatitis"},{"key":"2021122015113838600_CIT0017","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.ssci.2014.04.012","article-title":"Why are occupational health and safety training approaches not effective? Understanding young worker learning processes using an ergonomic lens","volume":"68","author":"Laberge","year":"2014","journal-title":"Saf Sci;"},{"key":"2021122015113838600_CIT0018","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s13063-016-1255-y","article-title":"A behavioural change package to prevent hand dermatitis in nurses working in the national health service (the SCIN trial): study protocol for a cluster randomised controlled trial","volume":"17","author":"Madan","year":"2016","journal-title":"Trials"},{"key":"2021122015113838600_CIT0019","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/jdv.14315","article-title":"The Eastern European experience on occupational skin diseases. Make underreporting an issue?","volume":"31","author":"Moldovan","year":"2017","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2021122015113838600_CIT0020","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1600-0536.2010.01763.x","article-title":"Evidence-based guidelines for the prevention, identification and management of occupational contact dermatitis and urticaria","volume":"63","author":"Nicholson","year":"2010","journal-title":"Contact Dermatitis"},{"key":"2021122015113838600_CIT0022","year":"2019"},{"key":"2021122015113838600_CIT0023","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/cod.12603","article-title":"Skin health and safety at work in Croatian hairdressing apprentices","volume":"75","author":"Samard\u017ei\u0107","year":"2016","journal-title":"Contact Dermatitis"},{"key":"2021122015113838600_CIT0024","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.0105-1873.2005.00557.x","article-title":"Transepidermal water loss and incidence of hand dermatitis in a prospectively followed cohort of apprentice nurses","volume":"52","author":"Schmid","year":"2005","journal-title":"Contact Dermatitis"},{"key":"2021122015113838600_CIT0025","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/s13063-017-1803-0","article-title":"The effectiveness of a skin care program for the prevention of contact dermatitis in health care workers (the healthy hands project): study protocol for a cluster randomized controlled trial","volume":"18","author":"Soltanipoor","year":"2017","journal-title":"Trials"},{"key":"2021122015113838600_CIT0026","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.0105-1873.2003.00159.x","article-title":"Nordic Occupational Skin Questionnaire (NOSQ-2002): a new tool for surveying occupational skin diseases and exposure","volume":"49","author":"Susitaival","year":"2003","journal-title":"Contact Dermatitis"},{"key":"2021122015113838600_CIT0027","first-page":"8","article-title":"Dermal exposure and changes in skin barrier function of base metal refinery workers co-exposed to cobalt and nickel","volume":"19","author":"Van Aarde","year":"2013","journal-title":"Occup Health South Afr"},{"key":"2021122015113838600_CIT0028","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.shaw.2013.04.004","article-title":"Essential occupational safety and health interventions for low- and middle-income countries: an overview of the evidence","volume":"4","author":"Verbeek","year":"2013","journal-title":"Saf Health Work"},{"key":"2021122015113838600_CIT0029","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/cod.12131","article-title":"Wet work and hand eczema in apprentice nurses; part I of a prospective cohort study","volume":"70","author":"Visser","year":"2014","journal-title":"Contact Dermatitis"},{"key":"2021122015113838600_CIT0030","doi-asserted-by":"crossref","first-page":"263","DOI":"10.3109\/15569527.2011.574302","article-title":"The effect of damaged skin barrier induced by subclinical irritation on the sequential irritant contact dermatitis","volume":"30","author":"Wu","year":"2011","journal-title":"Cutan Ocul Toxicol"}],"container-title":["Annals of Work Exposures and Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/annweh\/article-pdf\/65\/2\/167\/41826255\/wxaa122.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/annweh\/article-pdf\/65\/2\/167\/41826255\/wxaa122.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T15:13:54Z","timestamp":1640013234000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/annweh\/article\/65\/2\/167\/6131637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,9]]},"references-count":29,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,2,9]]},"published-print":{"date-parts":[[2021,3,3]]}},"URL":"https:\/\/doi.org\/10.1093\/annweh\/wxaa122","relation":{},"ISSN":["2398-7308","2398-7316"],"issn-type":[{"value":"2398-7308","type":"print"},{"value":"2398-7316","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,3,1]]},"published":{"date-parts":[[2021,2,9]]}}}