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In order to address community concerns surrounding secondhand illicit substance exposure and better protect harm reduction workers, a validated sampling and LC\u2013MS\/MS analysis method was developed for 6 illicit drugs: fentanyl, heroin, methamphetamine, cocaine, etizolam, and bromazolam. It was found that the filter used needed to be silanized to be made more inert and avoid loss of analyte due to degradation. Using the silanized filters, recoveries were good (&amp;gt;90%) and the collected samples were found to be stable at room temperature for 2 wk. The sampling volume validated was up to 960 L. The sensitivity and range of the method make it appropriate for short-term (15 min), full shift (8 h), or environmental sampling.<\/jats:p>","DOI":"10.1093\/annweh\/wxae048","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T19:11:02Z","timestamp":1715973062000},"page":"756-764","source":"Crossref","is-referenced-by-count":7,"title":["Validation of a sampling method and liquid chromatography mass spectrometry analysis method for measurement of fentanyl and five other illicit drugs"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8188-8993","authenticated-orcid":false,"given":"Matthew","family":"Jeronimo","sequence":"first","affiliation":[{"name":"School of Population and Public Health, University of British Columbia , 2206 East Mall, Vancouver, British Columbia, V6T 1Z3 , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly","family":"Mastel","sequence":"additional","affiliation":[{"name":"School of Population and Public Health, University of British Columbia , 2206 East Mall, Vancouver, British Columbia, V6T 1Z3 , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasleen","family":"Gill","sequence":"additional","affiliation":[{"name":"School of Population and Public Health, University of British Columbia , 2206 East Mall, Vancouver, British Columbia, V6T 1Z3 , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8258-6890","authenticated-orcid":false,"given":"Hugh","family":"Davies","sequence":"additional","affiliation":[{"name":"School of Population and Public Health, University of British Columbia , 2206 East Mall, Vancouver, British Columbia, V6T 1Z3 , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"key":"2024080805514311200_CIT0001","author":"ACGIH","year":"2023"},{"issue":"3","key":"2024080805514311200_CIT0002","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/10482911211039566","article-title":"Occupational safety and health and illicit opioids: State of the research on protecting against the threat of occupational exposure","volume":"31","author":"Basham","year":"2021","journal-title":"New Solut"},{"key":"2024080805514311200_CIT0003","author":"BCCDC","year":"2024"},{"key":"2024080805514311200_CIT0004","author":"BC Ministry of Health","year":"2016"},{"key":"2024080805514311200_CIT0005","author":"BC Coroners Service","year":"2023"},{"issue":"12","key":"2024080805514311200_CIT0006","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1002\/jssc.200700039","article-title":"Detection of cocaine in the airborne particles of the Italian cities Rome and Taranto","volume":"30","author":"Cecinato","year":"2007","journal-title":"J Sep Sci"},{"issue":"5","key":"2024080805514311200_CIT0007","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1016\/j.scitotenv.2008.11.004","article-title":"Occurrence of cocaine in the air of the World\u2019s cities: an emerging problem? 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