{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T09:06:45Z","timestamp":1769072805958,"version":"3.49.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Working Environment Research Fund","award":["20175100924"],"award-info":[{"award-number":["20175100924"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim was to estimate the prevalence and risk of respiratory symptoms among workers exposed to epoxy resin systems in the wind turbine industry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross-sectional study including 180 epoxy-exposed production workers from two Danish wind turbine blade factories and 41 non-exposed office workers. Respiratory symptoms were defined as having two or more symptoms (i.e. wheezing in chest, waking up with chest tightness, shortness of breath, attack of coughing, or asthma attack) within the last 12 mo. Epoxy exposure was defined as exposure status (epoxy-exposed production worker or non-exposed office worker) and years of epoxy-exposure (years of employment as production worker). Epoxy skin sensitization status was obtained through a patch-test. The association between epoxy-exposure and respiratory symptoms was estimated using modified Poisson regression (prevalence ratio (PR)) adjusting for smoking and age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 13.3% of the epoxy-exposed production workers and 4.9% of non-exposed office workers reported two or more respiratory symptoms (PRadj=1.8, 95% CI 0.4-9.5). For years of exposure, PRadj values were 1.2 (&amp;lt;1 yr), 1.0 (\u22651-&amp;lt;5 yr), and 2.6 (\u22655 yr). Higher PRadj were found among men. Epoxy-sensitized production workers had a PRadj of 0.4, while non-sensitized workers had a PRadj of 1.9, compared to non-exposed office workers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Epoxy-exposed production workers showed a tendency to report respiratory symptoms more often than non-exposed office workers. However, we found no clear association between exposure duration and symptoms. Further studies are highly warranted to evaluate the potential association between epoxy exposure and respiratory symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/annweh\/wxaf045","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T11:55:38Z","timestamp":1754049338000},"source":"Crossref","is-referenced-by-count":0,"title":["Respiratory symptoms among epoxy-exposed workers in the wind turbine industry: a cross-sectional study"],"prefix":"10.1093","volume":"70","author":[{"given":"Christine Marie","family":"Eggertsen","sequence":"first","affiliation":[{"name":"Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital , Aarhus ,","place":["Denmark"]},{"name":"Faculty of Health, Aarhus University , Aarhus ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annett","family":"Dalb\u00f8ge","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital , Aarhus ,","place":["Denmark"]},{"name":"Institute of Clinical Medicine, Aarhus University , Aarhus ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per Axel","family":"Clausen","sequence":"additional","affiliation":[{"name":"National Research Centre for the Working Environment , Copenhagen ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8247-6576","authenticated-orcid":false,"given":"Jakob","family":"B\u00f8nl\u00f8kke","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, Danish Ramazzini Centre, Aalborg University Hospital , Aalborg ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik Albert","family":"Kolstad","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital , Aarhus ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marl\u00e9ne","family":"Isaksson","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Dermatology, Skane University Hospital, Lund University , Malm\u00f6 ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ole","family":"Carstensen","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine - University Research Clinic, Danish Ramazzini Centre, Regional Hospital Goedstrup , Herning ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4915-1734","authenticated-orcid":false,"given":"Vivi","family":"Schl\u00fcnssen","sequence":"additional","affiliation":[{"name":"Department of Public Health, Research Unit for Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University , Aarhus ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra Golabek","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital , Aarhus ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,16]]},"reference":[{"key":"2026012112115360700_CIT0019","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/cod.12445","article-title":"Occupational allergic contact dermatitis caused by epoxy chemicals: occupations, sensitizing products, and diagnosis","volume":"73","author":"Aalto-Korte","year":"2015","journal-title":"Contact Dermatitis"},{"key":"2026012112115360700_CIT0001","volume-title":"Arbejde med epoxy- og isocyanatholdige produkter","author":"Arbejdstilsynet","year":"2019"},{"key":"2026012112115360700_CIT0002","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/j.1600-0536.2012.02072.x","article-title":"Contact allergy to epoxy resin: risk occupations and consequences","volume":"67","author":"Bangsgaard","year":"2012","journal-title":"Contact Dermatitis"},{"key":"2026012112115360700_CIT0003","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s00420-013-0866-9","article-title":"Allergens causing occupational asthma: an evidence-based evaluation of the literature","volume":"87","author":"Baur","year":"2014","journal-title":"Int Arch Occup Environ Health"},{"key":"2026012112115360700_CIT0004","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1111\/bjd.21830","article-title":"Prevalence of skin sensitization and dermatitis among epoxy","volume":"187","author":"Christiansen","year":"2022","journal-title":"Br J Dermatol"},{"key":"2026012112115360700_CIT0005","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1093\/annweh\/wxac074","article-title":"The relationship between potential occupational sensitizing exposures and asthma: an overview of systematic reviews","volume":"67","author":"Dalb\u00f8ge","year":"2023","journal-title":"Ann. Work Expo. Health"},{"key":"2026012112115360700_CIT0006","doi-asserted-by":"publisher","first-page":"146","DOI":"10.5271\/sjweh.4214","article-title":"A systematic review of the relation between ten potential occupational sensitizing exposures and asthma","volume":"51","author":"Dalb\u00f8ge","year":"2025","journal-title":"Scand J Work Environ Health"},{"key":"2026012112115360700_CIT0007","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/978-94-011-7073-4_29","article-title":"History and Development of Epoxy Resins","volume-title":"High Performance Polymers: Their Origin and Development","author":"Gannon","year":"1986"},{"key":"2026012112115360700_CIT0008","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/cod.12491","article-title":"Sensitization to reactive diluents and hardeners in epoxy resin systems. IVDK data 2002\u20132011. Part I: reaction frequencies","volume":"74","author":"Geier","year":"2016","journal-title":"Contact Dermatitis"},{"key":"2026012112115360700_CIT0009","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1111\/cts.12341","article-title":"Cross-sectional study of respiratory symptoms, spirometry, and immunologic sensitivity in epoxy resin workers","volume":"8","author":"Hines","year":"2015","journal-title":"Clin Transl Sci"},{"key":"2026012112115360700_CIT0010","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1111\/cod.12432","article-title":"European Society of Contact Dermatitis guideline for diagnostic patch testing - recommendations on best practice","volume":"73","author":"Johansen","year":"2015","journal-title":"Contact Dermatitis"},{"key":"2026012112115360700_CIT0011","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1021\/tx900193s","article-title":"Reduced sensitizing capacity of epoxy resin systems: a structure-activity relationship study","volume":"22","author":"Niklasson","year":"2009","journal-title":"Chem Res Toxicol"},{"key":"2026012112115360700_CIT0012","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1136\/oem.48.11.783","article-title":"Respiratory effects of exposure of shipyard workers to epoxy paints","volume":"48","author":"Rempel","year":"1991","journal-title":"Br J Ind Med"},{"key":"2026012112115360700_CIT0013","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s12989-016-0148-2","article-title":"Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition","volume":"13","author":"Saber","year":"2016","journal-title":"Part Fibre Toxicol"},{"key":"2026012112115360700_CIT0014","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1196\/annals.1371.010","article-title":"Epoxy Resins in the Construction Industry","volume":"1076","author":"SPEE","year":"2006","journal-title":"Ann N Y Acad Sci"},{"key":"2026012112115360700_CIT0015","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.jaip.2018.07.023","article-title":"Occupational asthma from epoxy compounds","volume":"7","author":"Suojalehto","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"2026012112115360700_CIT0016","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.arbres.2018.01.030","article-title":"Factors affecting lung function: a review of the literature","volume":"54","author":"Talaminos Barroso","year":"2018","journal-title":"Arch Bronconeumol"},{"key":"2026012112115360700_CIT0017","doi-asserted-by":"publisher","first-page":"281","DOI":"10.2486\/indhealth.37.281","article-title":"Prevention of occupational allergy caused by exposure to acid anhydrides","volume":"37","author":"Yokota","year":"1999","journal-title":"Ind Health"},{"key":"2026012112115360700_CIT0018","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1093\/aje\/kwh090","article-title":"A modified poisson regression approach to prospective studies with binary data","volume":"159","author":"Zou","year":"2004","journal-title":"Am J Epidemiol"}],"container-title":["Annals of Work Exposures and Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/annweh\/article-pdf\/70\/1\/wxaf045\/64278768\/wxaf045.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/annweh\/article-pdf\/70\/1\/wxaf045\/64278768\/wxaf045.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T17:12:00Z","timestamp":1769015520000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/annweh\/article\/doi\/10.1093\/annweh\/wxaf045\/8254990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,16]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,21]]}},"URL":"https:\/\/doi.org\/10.1093\/annweh\/wxaf045","relation":{},"ISSN":["2398-7308","2398-7316"],"issn-type":[{"value":"2398-7308","type":"print"},{"value":"2398-7316","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1]]},"published":{"date-parts":[[2025,9,16]]},"article-number":"wxaf045"}}