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Twenty wireless sensors monitored CO2, PM2.5, and TVOCs across three ventilation scenarios over 12 days. Period-based compliance assessment across 57 shift periods showed 93.0% maintained full regulatory standards, with the optimized periodic ventilation scenario achieving 100% compliance. Periodic fresh air bursts (15-minute cycles every 4\u2005hours) maintained air quality while achieving 70\u201375% energy reduction. Results suggest substantial energy savings may be achievable without compromising worker safety.<\/jats:p>","DOI":"10.1093\/annweh\/wxag041","type":"journal-article","created":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T11:31:33Z","timestamp":1779017493000},"source":"Crossref","is-referenced-by-count":0,"title":["Optimizing ventilation in large-scale fulfillment centers: balancing indoor air quality, energy efficiency, and worker health"],"prefix":"10.1093","volume":"70","author":[{"given":"Angela Maria","family":"Andreica","sequence":"first","affiliation":[{"name":"Department of Industrial Engineering, University of Petro\u0219ani , Petro\u0219ani 332006 ,","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103d\u0103lin","family":"Andreica","sequence":"additional","affiliation":[{"name":"Department of Industrial Engineering, University of Petro\u0219ani , Petro\u0219ani 332006 ,","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103d\u0103lina","family":"D\u0103nil\u0103","sequence":"additional","affiliation":[{"name":"Faculty of Physics, Babe\u0219-Bolyai University , Cluj-Napoca 400084 ,","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,5,29]]},"reference":[{"key":"2026052913542551400_wxag041-B1","doi-asserted-by":"publisher","first-page":"2579","DOI":"10.3390\/buildings15142579","article-title":"Mechanical ventilation strategies in buildings: a comprehensive review of climate management, indoor air quality, and energy efficiency","volume":"14","author":"Almeida","year":"2024","journal-title":"Buildings"},{"key":"2026052913542551400_wxag041-B2","doi-asserted-by":"publisher","first-page":"4722","DOI":"10.3390\/ijerph17134722","article-title":"Impact of CO2 concentrations on human work performance and cellular metabolic effects","volume":"17","author":"Azuma","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"2026052913542551400_wxag041-B3","volume-title":"BS 40102:2023. 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